NCT06627582

A Study on Pain After Breast Reconstruction

Persistent Postmastectomy Pain: Defining the Burden of Disease and the Role of Surgical Reinnervation in Patients With Breast Reconstruction

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 274 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer. The study will also look at how effective regenerative peripheral nerve interface (RPNI) surgery is for reducing pain from neuropathic PPMP after breast reconstruction.

Conditions

• Mastectomy
• Mastectomy Patient
• Mastectomy and Breast Reconstruction
• Breast Reconstruction
• Breast Reconstruction After Mastectomy
• Postmastectomy Pain

Interventions

Type	Name	Description
BEHAVIORAL	PROMIS Scale v2.0 - Pain Intensity 3a	PROMIS Scale v2.0 - Pain Intensity 3a is a 3-question short form in which patients rate their worst, average, and current level of pain during the past 7 days.
BEHAVIORAL	PROMIS 29+2	PROMIS 29+2 (PROMIS-Preference, PROPr) is a compilation of item banks to assess pain intensity
BEHAVIORAL	PROMIS Scale v2.0 - Nociceptive Pain Quality 5a	5-question short form that identifies patients who have experienced nociceptive pain during the past 7 days
BEHAVIORAL	PROMIS Scale v2.0 - Neuropathic Pain Quality 5a	5-question short form that identifies patients who have experienced neuropathic pain during the past 7 days

Timeline

• Start date: 2024-10-01
• Primary completion: 2027-10-01
• Completion: 2027-10-01
• First posted: 2024-10-04
• Last updated: 2026-03-27

Locations

7 sites across 1 country: United States