| Recruiting | Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care NCT07089602 | BioLab Holdings | Phase 4 |
| Not Yet Recruiting | Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia NCT06326203 | UPECLIN HC FM Botucatu Unesp | Phase 1 / Phase 2 |
| Recruiting | Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer Care NCT06153589 | University Hospital Center of Martinique | N/A |
| Recruiting | Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Non NCT06674980 | C5 Biomedical | N/A |
| Recruiting | Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard NCT06826339 | Tiger Biosciences, LLC. | Phase 4 |
| Recruiting | Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs NCT06560502 | Stability Biologics | N/A |
| Completed | Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations NCT07350811 | Versailles Hospital | — |
| Completed | Time to Heal (Wound, Healing, Dialogue, Nutrition) NCT06255288 | Hvidovre University Hospital | N/A |
| Unknown | Geko™ KM40C Hydrogel Skin Adhesion Trial (XW-3) NCT06084546 | Firstkind Ltd | N/A |
| Completed | Evaluation of the Efficacy of Multilayer Compression & UrgoStart Plus NCT06007703 | Gloucestershire Hospitals NHS Foundation Trust | — |
| Withdrawn | Efficacy of Kerecis Omega 3 in Comparison to Clinical Standard Procedures NCT06036485 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds NCT05619237 | Chester Ho, MD | N/A |
| Terminated | Efficacy Study for Geko Device in VLU Patients (Canada) NCT05057793 | Firstkind Ltd | N/A |
| Recruiting | Topical Sevoflurane for Treatment of Chronic Leg Ulcers NCT05303805 | Charles University, Czech Republic | Phase 4 |
| Completed | Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice NCT05148390 | BSN Medical GmbH | — |
| Unknown | Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in NCT05274295 | Szeged University | N/A |
| Terminated | Electrostimulation System WoundEL for Leg Ulcers Healing ( NCT04980898 | CEN Biotech | N/A |
| Completed | Haemodynamics Variations of Transcutaneous Oxygen in Patient With Areterio-venous Leg Ulcers Under Venous Comp NCT03725111 | University Hospital, Caen | N/A |
| Completed | Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wou NCT03644849 | St. Louis University | N/A |
| Completed | Efficacy Study for Geko Device in VLU Patients NCT03396731 | Firstkind Ltd | N/A |
| Unknown | Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Isch NCT02993809 | South China Research Center for Stem Cell and Regenerative Medicine | Phase 1 |
| Terminated | Speckle Study: In Arterial, Mixed and Diabetic Foot Ulcers NCT03186560 | Firstkind Ltd | N/A |
| Completed | Evaluation Of An Advanced Borderless Dressing NCT03146845 | Smith & Nephew, Inc. | N/A |
| Withdrawn | Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs NCT02988063 | OhioHealth | Phase 4 |
| Unknown | Pain in Chronic Leg- and Foot Ulcers NCT03086577 | University College of Southeast Norway | — |
| Unknown | Utility of Samples in Bacteriological Prospective Series of Ulcers Leg Infected Clinically NCT02889926 | Fondation Hôpital Saint-Joseph | N/A |
| Unknown | Remote Ischemic Conditioning for Treatment of Chronic Wounds NCT02873728 | Soroka University Medical Center | N/A |
| Unknown | Treatment of Chronic Leg Ulcers With Autologous Stromal Vascular Fraction NCT02987101 | Odense University Hospital | N/A |
| Unknown | Study of VF001-DP in Patients With Chronic Venous Leg Ulcers NCT02973893 | Factor Therapeutics Ltd. | Phase 2 |
| Completed | SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer NCT02600390 | Prolong Pharmaceuticals | Phase 2 |
| Completed | Effects of Topical Dynamic Phototherapy on the Microbiota of Chronic Wounds NCT02392390 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence NCT02626156 | Medical University of South Carolina | Phase 2 |
| Completed | When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care? NCT02889913 | Fondation Hôpital Saint-Joseph | — |
| Unknown | Safety and Efficacy of Autologous Bone Marrow Stem Cells for Lower Extremity Ischemia Treating NCT01903044 | Pontifícia Universidade Católica do Paraná | Phase 1 / Phase 2 |
| Unknown | Clinical Feasibility of an Advanced Therapy Medicinal Product (ATMP) Preparation for Autologous Skin Regenerat NCT02842502 | Centre Hospitalier Universitaire de Besancon | N/A |
| Completed | Use of dHACM in the Treatment of Venous Leg Ulcers NCT02011503 | MiMedx Group, Inc. | N/A |
| Terminated | Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot NCT01966380 | Molnlycke Health Care AB | Phase 2 |
| Completed | The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study NCT01770509 | M.D. Lederman Consulting Ltd | Phase 1 / Phase 2 |
| Completed | Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds NCT01551667 | Centre Hospitalier Universitaire de Nīmes | — |
| Terminated | Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity Ulcers NCT01657318 | De La Salle University Medical Center | — |
| Completed | Study to Evaluate the Performance of AQUACEL® Extra™ in Venous Leg Ulcers NCT01591434 | ConvaTec Inc. | Phase 3 |
| Completed | EASH Dressing on Chronic Venous Leg Ulcers NCT01497210 | ConvaTec Inc. | Phase 2 |
| Terminated | Comparison of the Use of VAC System in Transplants of Leg Ulcers Versus Usual Dressing Method NCT02509533 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | Evaluation of a Ionic Silver and Honey Preparation to Treat Chronic Wounds of the Lower Legs NCT01111695 | University Hospital, Geneva | Phase 2 |
| Completed | AQUACEL® Ag Dressing and Urgotul® Silver Dressing on Healing of Chronic Venous Leg Ulcers NCT01084577 | ConvaTec Inc. | Phase 4 |
| Terminated | Reduction of Bacteria in MRSA Positive Ulcers NCT00771368 | Nitric BioTherapeutics, Inc | Phase 1 / Phase 2 |
| Completed | THERMES ET VEINES: Spa for Prevention of Leg Ulcers NCT00838500 | Association Francaise pour la Recherche Thermale | Phase 3 |
| Unknown | Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening Ischemia NCT00434616 | Franziskus-Krankenhaus | Phase 2 / Phase 3 |
| Completed | Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study NCT00759889 | Southwest Regional Wound Care Center | — |
| Completed | Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers NCT00399308 | Shire | Phase 1 / Phase 2 |
| Completed | Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI) NCT00371371 | UMC Utrecht | Phase 1 / Phase 2 |
| Unknown | The Evaluation of OrCel for the Treatment of Venous Ulcers NCT00270972 | Ortec International | N/A |
| Unknown | Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg U NCT00232973 | Intercytex | Phase 3 |
| Recruiting | A Real-World Registry of Chronic Wounds and Ulcers NCT02280733 | U.S. Wound Registry | — |
| Completed | A Study to Evaluate the Clinical Effectiveness of a Collagen-ORC Antimicrobial Matrix in Venous Leg Ulcers NCT00235209 | Ethicon, Inc. | Phase 4 |
| Completed | Research of Prognostic Factors Associated With Healing of Venous Leg Ulcers NCT01673412 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | A Randomised Controlled Trial Comparing Vacuum Assisted Closure (V.A.C.®) With Modern Wound Dressings NCT00243620 | Maastricht University Medical Center | N/A |
| Completed | VEGF Gene Transfer for Critical Limb Ischemia NCT00304837 | Losordo, Douglas, M.D. | Phase 1 |