NCT02889913

When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care?

When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care? Retrospective Study of 100 Consecutive Biopsies

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Fondation Hôpital Saint-Joseph · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Leg ulcers are frequent. There are no epidemiological studies available in France, but international studies estimate the prevalence between 0.045 and 0.63% of the total population, prevalence increases with age, reaching 5% of patients over 80 years. Extrapolating these prevalences in the French population between 28 000 and 395 000 people are affected in France a leg ulcer. It is a costly disease. In 2001, a French study conducted among 800 physicians, including 85.7% of general practitioners, involving more than 1000 patients with venous ulcers, it was estimated that the total cost of treatment per patient average was 888 32 euros. This is truly a public health problem. Leg ulcers are in 80% of cases of vascular causes (venous, arterial or arteriovenous mixed). However, there are rare causes of ulcers: skin carcinoma, infectious ulcers and vasculitis. These ulcers rare causes require specific treatments that can often heal. To diagnose, to perform a skin biopsy. Thus, the general practitioner must know when to put the indication for biopsy of a leg ulcer.

Detailed description

Goal : Analyzing the last 100 consecutive skin biopsies performed in patients carriers of chronic leg ulcers, followed in the vascular medicine department of the Hospital Saint Joseph Paris, to determine: * The reasons which motivated the doctor make the indication of biopsy: * Disease duration of ulcer * Unusual clinical features * Other signs associated with ulcer * Absence of a satisfactory explanation vascular * The pathological results Purpose: To clear a typical profile ulcers biopsy Methodology : * Retrospective, single-center, * Acquisition of data: via the pathology laboratory of the hospital will be collected the last 100 consecutive biopsies performed with leg ulcers in vascular medicine department of the hospital Saint Joseph Paris, between 1 January 2013 and the October 1, 2013. Then be analyzed all paper and electronic records of these patients. * Grid and Analysis: * Patient histories, * vascular profile of patients, * clinical and chronological criteria of the ulcer, * Other signs associated with ulcer * Results of histological biopsies. * The data will be made anonymous on the grid for collection by a numbering system 1 100.

Conditions

• Varicose Ulcer
• Leg Ulcer

Interventions

Type	Name	Description
OTHER	No intervention only description	No intervention only description

Timeline

• Start date: 2015-01-01
• Primary completion: 2015-07-01
• Completion: 2015-07-01
• First posted: 2016-09-07
• Last updated: 2016-09-07

Locations

1 site across 1 country: France