| Not Yet Recruiting | Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b) NCT07526649 | Auckland City Hospital | N/A |
| Not Yet Recruiting | Intra-Arterial Tirofiban After Complete Recanalization for Acute Intracranial Large-Vessel Occlusion NCT07537933 | Shandong Provincial Hospital | Phase 3 |
| Recruiting | Intra-arterial Methylprednisolone After Endovascular Thrombectomy NCT07516522 | Tang-Du Hospital | Phase 2 |
| Not Yet Recruiting | Advancing Reperfusion Therapy for Ischemic Stroke: Direct Transfer to Angiography Suite for Patients With Susp NCT07460713 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspi NCT07231380 | Vanderbilt University Medical Center | N/A |
| Not Yet Recruiting | Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diag NCT07474675 | Boston Children's Hospital | — |
| Not Yet Recruiting | Head of Bed After Ischemic Stroke Thrombectomy (HoBIT) NCT07367633 | Population Health Research Institute | N/A |
| Recruiting | Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acu NCT07404852 | Washington University School of Medicine | N/A |
| Recruiting | Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours NCT07253181 | Xuanwu Hospital, Beijing | Phase 3 |
| Not Yet Recruiting | Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT NCT07168278 | The First Affiliated Hospital of University of Science and Technology of China | Phase 3 |
| Completed | Sodium Sivelestat With Mechanical Thrombectomy for Acute Stroke: A Pilot Study NCT07196605 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Evaluation of the CONDA Stent Retriever in Acute Ischemic Stroke NCT07174505 | Anaconda Biomed S.L. | N/A |
| Recruiting | Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort NCT06963489 | First Affiliated Hospital of Wannan Medical College | — |
| Not Yet Recruiting | Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke After Endovascular Treatment NCT06788626 | Wei Hu | Phase 3 |
| Terminated | Mechanical Thrombectomy Blood Flow Reversal NCT06721338 | MediSys Health Network | Phase 1 |
| Recruiting | Image Detection of Impaired Microcirculatory Reperfusion NCT07099599 | University of Cincinnati | — |
| Recruiting | Combination of Hypothermia and Thrombectomy in Acute Stroke NCT06301412 | University of Freiburg | Phase 3 |
| Recruiting | Thrombectomy Versus Best Medical Management in Large Vessel Occlusion Stroke Patients Presenting Beyond 24 Hou NCT06654375 | Tianjin Huanhu Hospital | N/A |
| Completed | Early Feasibility Study of RapidPulseTM Aspiration System for Patients With Acute Ischemic Stroke NCT05899036 | RapidPulse, Inc | N/A |
| Unknown | EFfects of Y-6 SUblingual Tablets foR PaTients With AcUte Ischemic StRokE (FUTURE) NCT06138834 | Beijing Tiantan Hospital | Phase 2 |
| Recruiting | Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke NCT06727006 | ASST Santi Paolo e Carlo | — |
| Completed | Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients NCT05953623 | Tianjin Huanhu Hospital | Phase 1 |
| Unknown | Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients Wi NCT05836766 | Beijing Tiantan Hospital | Phase 2 |
| Recruiting | Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study NCT05864638 | Changhai Hospital | — |
| Terminated | Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy NCT05592054 | Changhai Hospital | N/A |
| Unknown | Endovascular Treatment of Acute Ischemic Stroke With Underlying Intracranial Artery Stenosis NCT06260969 | Tianjin Huanhu Hospital | — |
| Completed | THUNDER: Acute Ischemic Stroke Study with the Penumbra System® Including Thunderbolt™ Aspiration Tubing NCT05437055 | Penumbra Inc. | N/A |
| Withdrawn | Study on the Efficacy and Safety of T-02 for the Treatment for Acute Ischemic Stroke NCT05342038 | Biomedical Solutions Inc. | N/A |
| Enrolling By Invitation | Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry NCT06702787 | Middle East North Africa Stroke and Interventional Neurotherapies Organization | — |
| Completed | Registry of Emergent Large VeSsel OCclUsion DuE to IntraCranial AtherosclerosiS NCT05403593 | Medical University of South Carolina | — |
| Recruiting | Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-2 NCT05659160 | Tianjin Huanhu Hospital | — |
| Recruiting | Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke NCT06456437 | Ming Wei | — |
| Terminated | Safety and Efficacy of Intracranial Thrombus Aspiration Catheter in the Treatment of Acute Large-vessel Occlus NCT05101668 | Sinomed Neurovita Technology Inc. | N/A |
| Completed | Biomarkers algOrithm for strOke diagnoSis and Treatment Resistance Prediction NCT04726839 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | A Prospective, Multi-center and Randomized Controlled Trial of Tianyi Revascularization Device in Acute Ischem NCT05496361 | Suzhou Zenith Vascular Scitech Co., Ltd. | N/A |
| Unknown | Regional Strategy for Transfer for Mechanical Thrombectomy NCT04046757 | University Hospital, Montpellier | — |
| Unknown | Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy (RECOVER) NCT03753061 | Ministry of Science and Technology of the People´s Republic of China | N/A |
| Completed | Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficien NCT03469206 | Changhai Hospital | N/A |
| Unknown | Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-1 (TRACK-LVO-1) NCT05885178 | Tianjin Huanhu Hospital | — |
| Recruiting | Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions (TRACK NCT06200753 | Tianjin Huanhu Hospital | — |