| Recruiting | Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correl NCT07273643 | University Hospital, Montpellier | — |
| Not Yet Recruiting | Single-dose Prophylactic INdomethacin in Extremely Preterm Infants NCT06572917 | University of British Columbia | Phase 2 |
| Recruiting | RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH NCT07205263 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | rhTNK-tPA Thrombolytic Removal of Intraventricular Hemorrhage NCT06814964 | Beijing Tiantan Hospital | Phase 1 |
| Recruiting | Lumbar Drainage of Intraventricular Hemorrhage NCT06510842 | University Hospital Heidelberg | N/A |
| Recruiting | International Care Bundle Evaluation in Cerebral Hemorrhage Research NCT06429332 | Region Skane | Phase 4 |
| Recruiting | Prediction of Undesired Obstruction in External Ventricular Drains. NCT06466811 | Nantes University Hospital | — |
| Recruiting | Optimization of Saturation Targets And Resuscitation Trial (OptiSTART) NCT05849077 | University of Texas Southwestern Medical Center | N/A |
| Completed | Therapy BRIDGE (Bringing Real-Time Instruction Via Developmental and Gestationally-appropriate Education/Coach NCT06256939 | Children's Hospital Medical Center, Cincinnati | N/A |
| Not Yet Recruiting | PUFAs in Preterm Infants NCT06045130 | The First Hospital of Jilin University | — |
| Recruiting | AFFECT Study for Patients With Intraventricular Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, and Ve NCT05649904 | Ohio State University | N/A |
| Recruiting | Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Uni NCT05568264 | Shirley Ryan AbilityLab | N/A |
| Completed | PRedicting OutcomeS in Preterm nEonates With thromboCyTopenia NCT06043050 | Leiden University Medical Center | — |
| Unknown | ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage NCT05204849 | University of Aarhus | N/A |
| Recruiting | Active Removal of IntraCerebral Hematoma Via Active Irrigation NCT05118997 | IRRAS | N/A |
| Completed | The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment o NCT05113381 | Integra LifeSciences Corporation | N/A |
| Completed | The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant NCT05311228 | Indonesia University | Phase 4 |
| Unknown | Protecting Brains and Saving Futures - the PBSF Protocol NCT03786497 | Protecting Brains Saving Futures | — |
| Completed | Sonographic QUantification of Venous Circulation In the Preterm Brain NCT04535375 | Universitair Ziekenhuis Brussel | N/A |
| Withdrawn | Evaluation of Long-term Neurodevelopment in Neonatal Encephalopathy by Infant Treadmill NCT03527498 | Children's Hospital of Fudan University | N/A |
| Terminated | Safety and Efficacy Outcomes Following Previously Administered Short-Term Treatment With SHP607 in Extremely P NCT04506619 | Oak Hill Bio Ltd | — |
| Unknown | Intranasal Human Milk for Intraventricular Hemorrhage NCT04225286 | The Hospital for Sick Children | N/A |
| Terminated | Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates NCT04538079 | University College Cork | — |
| Terminated | PRONTO: Artemis in the Removal of Intraventricular Hemorrhage in the Hyper-Acute Phase NCT04178746 | Penumbra Inc. | — |
| Recruiting | A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Prematur NCT03253263 | OHB Neonatology Ltd. | Phase 2 |
| Unknown | Minimising the Adverse Physiological Effects of Transportation on the Premature Infant NCT03754439 | University of Nottingham | — |
| Completed | Start or STop Anticoagulants Randomised Trial (SoSTART) NCT03153150 | University of Edinburgh | Phase 3 |
| Completed | MISA to NRDS：a Multicenter Study in China NCT04077333 | Peking University Third Hospital | N/A |
| Completed | Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy NCT03230032 | Nationwide Children's Hospital | N/A |
| Completed | Antibiotic "Dysbiosis" in Preterm Infants NCT02784821 | University of Florida | Phase 2 |
| Unknown | Deferred Cord Clamping Compared to Umbilical Cord Milking in Preterm Infants NCT02996799 | King Abdulaziz University | N/A |
| Completed | Prediction of Brain Injury in Premature Infants NCT02814383 | Baylor College of Medicine | — |
| Unknown | Simulation Efficacy in Neurosurgical Education NCT02988154 | Johannes Gutenberg University Mainz | — |
| Unknown | VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infant NCT02742454 | University of Virginia | N/A |
| Completed | Monitoring Outcome in Neonatal Thrombocytopenia NCT03110887 | Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research | — |
| Completed | Research a New Predictive Marker of Intraventricular Hemorrhage in Very Preterm Infants NCT02400853 | University Hospital, Rouen | N/A |
| Unknown | Rheolytic Thrombectomy For Adult Intraventricular Haemorrhage NCT02394678 | Karol Palwel Budohoski | N/A |
| Terminated | Delayed Cord Clamping in Very Low Birth Weight Infants NCT02337088 | University of Chicago | N/A |
| Terminated | Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH) NCT02386228 | St. Joseph's Hospital and Medical Center, Phoenix | — |
| Recruiting | Improving Outcomes for Patients With Life-Threatening Neurologic Illness NCT04189471 | University of Maryland, Baltimore | — |
| Completed | Placental Transfusion Project for Preterm Infants NCT02400697 | Indiana University | — |
| Completed | Neonatal Resuscitation With Intact Cord NCT02231411 | Sharp HealthCare | N/A |
| Completed | Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury NCT02221219 | Hong Huang | Phase 1 / Phase 2 |
| Completed | The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Prematu NCT01866982 | Sharp HealthCare | N/A |
| Completed | Observational Study in Preterm Infants With Intracranial Hemorrhage NCT01620203 | Nelson Claure | — |
| Terminated | The Risk of Intraventricular Hemorrhage With Flat Midline Versus Right-Tilted Flat Lateral Head Positions NCT01584375 | King Abdul Aziz General Hospital | N/A |
| Withdrawn | The Natural History of Procalcitonin in Hemorrhagic Stroke NCT01498705 | CAMC Health System | — |
| Withdrawn | Autologous Umbilical Cord Blood Transfusion for Preterm Neonates NCT01121328 | Sahar M.A. Hassanein, MD | Phase 1 |
| Completed | Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA NCT03452722 | University of Rijeka | — |
| Unknown | Prospective Randomized, Controlled Trial for Treatment of Intraventricular Hemorrhage NCT01064011 | Albany Medical College | N/A |
| Unknown | Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage NCT01098890 | University of Calgary | Phase 2 |
| Unknown | Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants NCT00910234 | China Medical University Hospital | Phase 1 / Phase 2 |
| Completed | Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III NCT00784134 | Johns Hopkins University | Phase 3 |
| Completed | Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome NCT00957840 | University of Utah | N/A |
| Completed | Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants NCT00875758 | Washington University School of Medicine | N/A |
| Completed | MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine NCT00809055 | Washington University School of Medicine | Phase 4 |
| Terminated | Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage NCT00665769 | Baylor College of Medicine | N/A |
| Terminated | Inhaled Nitric Oxide and Neuroprotection in Premature Infants NCT00515281 | University of Chicago | Phase 2 / Phase 3 |
| Completed | Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants NCT00818220 | University of Rhode Island | Phase 2 |
| Terminated | High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study NCT00589953 | Atlantic Health System | Phase 2 |
| Completed | Comparative Infection Rates for the Codman BACTISEAL TM External Ventricular Drainage (EVD) System NCT00197392 | Codman & Shurtleff | Phase 4 |
| Completed | Clinical Trial on Treatment of Intraventricular Hemorrhage NCT00650858 | Johns Hopkins University | Phase 2 |
| Completed | Effects of Delayed Cord Clamping in Very Low Birth Weight Infants NCT00840983 | University of Rhode Island | Phase 1 |
| Completed | Antenatal Betamethasone Compared to Dexamethasone - "BETACODE TRIAL" NCT00418353 | University of Oklahoma | N/A |
| Completed | Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial) NCT00014989 | The George Washington University Biostatistics Center | Phase 3 |