| Not Yet Recruiting | Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism NCT05114980 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Gre NCT07081997 | Ascendis Pharma Bone Diseases A/S | Phase 3 |
| Recruiting | A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® ( NCT07264634 | Ascendis Pharma A/S | — |
| Recruiting | A Global Pregnancy Registry to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to YORVIPATH® (P NCT07345494 | Ascendis Pharma A/S | — |
| Recruiting | Parathyroid Allotransplant for Treatment of Hypoparathyroidism NCT06961071 | Peter Stock | Phase 1 / Phase 2 |
| Recruiting | Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine NCT07083557 | Bettina Mittendorfer | — |
| Recruiting | Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism NCT07530705 | Peking Union Medical College Hospital | Phase 1 / Phase 2 |
| Not Yet Recruiting | Translation and Validation of the Hypoparathyroidism Patient Experience Scales (HPES) Questionnaire in Greek NCT07160348 | Aristotle University Of Thessaloniki | — |
| Recruiting | Efficacy and Safety of XH02 for the Treatment of Hypoparathyroidism NCT07197450 | Peking Union Medical College Hospital | EARLY_Phase 1 |
| Recruiting | A Phase 2 Trial Investigating the Safety, Tolerability and Efficacy of EXT608 in Adults With Hypoparathyroidis NCT06988670 | Extend Biosciences Inc. | Phase 2 |
| Not Yet Recruiting | Tunisian Clinical Registry on Hypoparathyroidism and Pseudo-hypoparathyroidism NCT06445036 | Dacima Consulting | — |
| Recruiting | Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidis NCT06547151 | Amorphical Ltd. | Phase 2 |
| Recruiting | Institution of an Italian Multicenter Database of Patients Affected by Hypoparathyroidism or Pseudohypoparathy NCT06645899 | F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore | — |
| Active Not Recruiting | Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroid NCT06531941 | MBX Biosciences | Phase 2 |
| Completed | Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism NCT06465108 | MBX Biosciences | Phase 2 |
| Completed | Palopegteriparatide in Chronic Hypoparathyroidism NCT07299838 | National and Kapodistrian University of Athens | — |
| Completed | Cardiovascular, Renal, and Skeletal Complications in Patients With Post-Surgical Hypoparathyroidism NCT06419270 | University of Aarhus | — |
| Completed | Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous For NCT05965167 | Entera Bio Ltd. | Phase 1 |
| Completed | Endocrine Determinants of Renal Function in Patients With Hypoparathyroidism NCT06449729 | IRCCS San Raffaele | — |
| Completed | Near-Infrared Autofluorescence With PTH Test Strip as an SOP of Parathyroid in Thyroid Surgery NCT05684029 | Fujian Medical University | — |
| Recruiting | Hypoparathyroidism Natural History Study NCT05793853 | Columbia University | — |
| Terminated | Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography NCT05328076 | IRCCS San Raffaele | — |
| Completed | Intraoperative Methylene Blue Spray for the Identification and Preservation of Vital Structures in Thyroidecto NCT07395388 | Services Hospital, Lahore | N/A |
| Recruiting | Establishment of a Registry of Patients With Parathyroid Disease NCT06797934 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands Duri NCT05022667 | University of Michigan | N/A |
| Completed | Near-infrared Autofluorescence (NIRAF)-Guided Total Thyroidectomy: Impact in Low-volume, Non-parathyroid Insti NCT05043584 | Regional Hospital West Jutland | N/A |
| Completed | PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults NCT05387070 | Visen Pharmaceuticals (Shanghai) Co., Ltd. | Phase 3 |
| Completed | Determination of Circulating Autotaxin in Patients With GNAS or PTH Abnormalities NCT04671719 | Hospices Civils de Lyon | — |
| Completed | Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa). NCT04750460 | Saint Petersburg State University, Russia | Phase 3 |
| Completed | A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With NCT04701203 | Ascendis Pharma Bone Diseases A/S | Phase 3 |
| Completed | Diagnostic Accuracy Study of Indocyanine Green for Perfusion Assessment NCT06579430 | University Medical Center Groningen | EARLY_Phase 1 |
| Terminated | A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidi NCT04209179 | Chugai Pharmaceutical | Phase 1 |
| Completed | Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy NCT04372225 | Aix Marseille Université | — |
| Completed | Quality of Life Evaluation (SF-36) in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy (Qo NCT04053647 | Nantes University Hospital | — |
| Completed | QoL and Cognitive Function in Patients With Hypoparathyroidism NCT04569604 | University of Aarhus | — |
| Completed | A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism NCT04009291 | Ascendis Pharma A/S | Phase 2 |
| Unknown | Monocentric Study on the Use of Teriparatide in Children With hypoparathyroïdism NCT04126941 | Hospices Civils de Lyon | — |
| Completed | Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY) NCT04059380 | University of Roma La Sapienza | — |
| Terminated | Safety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidism NCT03364738 | Shire | Phase 3 |
| Completed | Effects of a Liquid Meal and Gut Hormones (GIP and GLP-2) on Bone Remodeling in Participants With Hypoparathyr NCT03728959 | University of Copenhagen | N/A |
| Completed | Oral PTH(1-34) PK and PD Study in Patients With Hypoparathyroidism NCT03516773 | Entera Bio Ltd. | Phase 2 |
| Unknown | Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery NCT03514251 | Bo Wang,MD | N/A |
| Completed | A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Con NCT03324880 | Shire | Phase 4 |
| Completed | Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study NCT03747029 | Azienda Ospedaliero-Universitaria di Modena | — |
| Completed | Study of rhPTH(1-84) in Japanese Healthy Subjects Compared With Matched Caucasian Healthy Adult Subjects NCT03150108 | Shire | Phase 1 |
| Completed | Study to Assess the Blood Concentrations and Actions of Recombinant Human Parathyroid Hormone (rhPTH [1-84]) W NCT02781844 | Shire | Phase 1 |
| Completed | A Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidism NCT02910466 | Shire | Phase 4 |
| Recruiting | Survey on Epidemiology of Hypoparathyroidism in France NCT02838927 | European Georges Pompidou Hospital | — |
| Unknown | Corticosteroid Rhythms in Hypoparathyroid Patients NCT02986607 | University of Bergen | EARLY_Phase 1 |
| Completed | A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARA NCT05556629 | Shire | — |
| Completed | Burden of Illness in Hypoparathyroidism NCT03437174 | University of Wuerzburg | — |
| Completed | A Pilot Study to Assess the Safety and Efficacy of Oral PTH (1-34) in the Treatment of Hypoparathyroidism NCT02152228 | Entera Bio Ltd. | Phase 2 |
| Active Not Recruiting | A Registry for Participants With Chronic Hypoparathyroidism NCT01922440 | Takeda | — |
| Completed | A Study Comparing Amorphous Calcium Carbonate (ACC) Versus Crystalline Calcium CCS) in Hypoparathyroidism Pati NCT01815021 | Amorphical Ltd. | Phase 1 / Phase 2 |
| Terminated | A Single Arm Study Comparing ACC Supplement to CCS in Management of Hypoparathyroidism NCT06288490 | Amorphical Ltd. | N/A |
| Completed | Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thy NCT02924532 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | A Study to Investigate the Safety and Tolerability of NPSP558, for the Treatment of Adults With Hypoparathyroi NCT01455181 | Shire | Phase 3 |
| Completed | Hypoparathyroidism in Denmark NCT01498341 | University of Aarhus | — |
| Completed | A Open-label Study Investigating the Safety and Tolerability of NPSP558, a Recombinant Human Parathyroid Hormo NCT01297309 | Shire | Phase 3 |
| Completed | Study of Safety and Efficacy of a rhPTH[1-84] of Fixed Doses of 25 and 50 mcg in Adults With Hypoparathyroidis NCT01268098 | Shire | Phase 3 |
| Unknown | ADD-ON Study to Existing Hypoparathyroidism Studies NCT00856401 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | HEXT (Hypo EXTended): Effect of PTH on Skeleton in Hypoparathyroidism NCT01199614 | Columbia University | Phase 3 |
| Unknown | Vitamin D Levels and Postoperative Hypocalcemia After Total Thyroidectomy NCT01039714 | Aristotle University Of Thessaloniki | — |
| Completed | Magnesium Treatment in Hypoparathyroidism NCT00824226 | University of Tartu | N/A |
| Completed | Use of NPSP558 in the Treatment of Hypoparathyroidism NCT00732615 | Shire | Phase 3 |
| Completed | Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidis NCT00743782 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Completed | Treatment of Hypoparathyroidism With Subcutaneous PTH (1-84) Injections: Effects on Muscle Function and Qualit NCT00730210 | University of Aarhus | Phase 2 |
| Completed | Perioperative Parathormone Measurement and Sodium Bicarbonate Infusion Test After Total Thyroidectomy NCT00793689 | Aristotle University Of Thessaloniki | — |
| Terminated | Effects of PTH Replacement on Bone in Hypoparathyroidism NCT00395538 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 3 |
| Completed | Physiologic Regulation of FGF-23 NCT00356512 | National Institute of Dental and Craniofacial Research (NIDCR) | — |
| Completed | Does Treatment of Hypovitaminosis D Increase Calcium Absorption? NCT00581828 | University of Wisconsin, Madison | Phase 4 |
| Completed | Parathyroid and Thymus Transplantation in DiGeorge #931 NCT00566488 | Sumitomo Pharma Switzerland GmbH | Phase 1 |
| Completed | Bone Properties in Hypoparathyroidism: Effects of PTH NCT00473265 | John P. Bilezikian | Phase 2 / Phase 3 |
| Completed | Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired NCT00004361 | National Center for Research Resources (NCRR) | — |
| Completed | Treatment of Hypoparathyroidism With Synthetic Human Parathyroid Hormone 1-34 NCT00001304 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 |
| Approved For Marketing | Expanded Access Program of Palopegteriparatide in Patients With Hypoparathyroidism NCT05654701 | Ascendis Pharma Bone Diseases A/S | — |