NCT03747029

Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,038 (actual)
• Sponsor: Azienda Ospedaliero-Universitaria di Modena · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

Primary hyperparathyroidism (PHPT) and Hypoparathyroidism (HP) are two of the most frequent disorder of Calcium-Phosphorus (Ca-P) metabolism. The Ca/P ratio is an accurate tool to differentiate patients with PHPT from healthy subjects, according to a previous single-centre study. The reliability of this index is based on the fact that serum Ca and P are inversely related together either in healthy subjects or in patients with PHPT and HP.

Detailed description

The aim of this study is to investigate the accuracy and diagnostic value of Ca/P ratio in the diagnosis of primary hyperparathyroidism and hypoparathyroidism. The definition of a valid cut-off of serum Ca/P ratio for patients with these disorders will be of help especially in those patients with apparently normal biochemical profile, but suggestive for primary hyperparathyroidism and hypoparathyroidism.

Conditions

• Phosphorus and Calcium Disorders
• Parathyroid Diseases
• Hyperparathyroidism
• Hypoparathyroidism

Interventions

Type	Name	Description
OTHER	No intervention is provided	No intervention is provided

Timeline

• Start date: 2017-11-28
• Primary completion: 2018-12-31
• Completion: 2018-12-31
• First posted: 2018-11-20
• Last updated: 2021-02-09

Locations

1 site across 1 country: Italy