Clinical Trials Directory

Trials / Unknown

UnknownNCT04126941

Monocentric Study on the Use of Teriparatide in Children With hypoparathyroïdism

Bi-daily Injection of Subcutaneous Teriparatide in Children With Hypoparathyroidism: Single-center Experience

Status
Unknown
Phase
Study type
Observational
Enrollment
9 (estimated)
Sponsor
Hospices Civils de Lyon · Academic / Other
Sex
All
Age
2 Years – 18 Years
Healthy volunteers
Not accepted

Summary

Pediatric hypoparathyroidism is an orphan disease. Conventional management combines native and active vitamin D, calcium supplementation and sometimes phosphate binders, with the risk of long term hypercalciuria, nephrocalcinosis and further renal impairment. The use of teriparatide has been reported in adults (daily or bi-daily subcutaneous infusions) and in children (rather continuous subcutaneous infusion) as second-line therapy. The objective of this study is to obtain efficacy and safety data on the use of teriparatide in children with hypoparathyroidism to improve our knowledge of their management.

Conditions

Interventions

TypeNameDescription
OTHERSerum calcium concentrations resultsTo compare serum calcium concentrations results in patients with hypoparathyroidism before and three months after initiation of teriparatide therapy

Timeline

Start date
2019-06-01
Primary completion
2020-06-01
Completion
2020-12-01
First posted
2019-10-15
Last updated
2019-10-15

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04126941. Inclusion in this directory is not an endorsement.