| Not Yet Recruiting | Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy NCT07518862 | University Health Network, Toronto | — |
| Recruiting | High Flow Nasal Cannula and Mask Oxygenation in Patients With Visceral Obesity Undergoing Sedated Gastroscopy NCT07159022 | Shanghai Zhongshan Hospital | N/A |
| Completed | Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit NCT06621641 | Dr. Behcet Uz Children's Hospital | N/A |
| Recruiting | Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Chil NCT06425406 | Henan Provincial People's Hospital | N/A |
| Unknown | High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild NCT06306651 | Ain Shams University | N/A |
| Recruiting | High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs NCT06879600 | Nguyen Dang Thu | N/A |
| Unknown | Tracheal Positive Pressure During High Flow Nasal Oxygen Administration in Critically Ill Patients: a Physiolo NCT05467332 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Active Not Recruiting | Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertens NCT06582459 | The First People's Hospital of Neijiang | — |
| Recruiting | A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic N NCT05526534 | Sichuan Cancer Hospital and Research Institute | N/A |
| Recruiting | Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula T NCT06375538 | Shanghai Zhongshan Hospital | — |
| Completed | Ventilatory Effects of THRIVE During EBUS NCT05505279 | Rijnstate Hospital | Phase 3 |
| Unknown | Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) NCT05401474 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Effects of High-Flow Nasal Cannula on Exercise Outcomes in Lung Transplant Candidates: A Pilot Study NCT06620081 | Hospital Israelita Albert Einstein | N/A |
| Completed | Closed-loop Oxygen Control for High Flow Nasal Therapy NCT04965844 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep Apnea NCT04608331 | Peking University First Hospital | Phase 4 |
| Unknown | The Efficacy of High-flow Nasal Cannula Oxygen Therapy in Sepsis Patients NCT04560842 | Mackay Memorial Hospital | N/A |
| Completed | High Flow Nasal Cannula in Patients Undergoing ERCP Retrograde Cholangiopancreatography With Intravenous Sedat NCT04184089 | American University of Beirut Medical Center | N/A |
| Unknown | Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation NCT04481295 | National Hospital Organization Minami Kyoto Hospital | N/A |
| Completed | Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC NCT04471220 | National Hospital Organization Minami Kyoto Hospital | N/A |
| Completed | Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures NCT04353531 | Rush University Medical Center | — |
| Completed | Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS NCT04325906 | Rush University Medical Center | N/A |
| Unknown | High Flow Nasal Cannula in Immunocompromised Patient With Acute Respiratory Failure NCT04293991 | Ain Shams University | N/A |
| Unknown | The Physiological Effect of High Flow Oxygen Therapy NCT04212182 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Completed | Weaning Protocol for High Flow Nasal Cannula Oxygen Therapy NCT03845244 | Seoul National University Hospital | N/A |
| Unknown | High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstruc NCT03449056 | Poitiers University Hospital | Phase 3 |
| Completed | The Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula NCT06146439 | Dr. Behcet Uz Children's Hospital | — |
| Completed | Effects of High-Flow Nasal Cannula Therapy Assessed by Electrical Impedance Tomography NCT04245241 | Peking Union Medical College Hospital | — |
| Completed | Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC) NCT03529994 | Christiana Care Health Services | — |
| Completed | Evaluation on the Efficacy of Bronchodilator Nebulization Via High Flow Nasal Cannula NCT03091504 | Rush University Medical Center | N/A |
| Completed | High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients NCT03148262 | University of Texas Southwestern Medical Center | N/A |
| Completed | A Multicentered Study on Efficiency of Noninvasive Ventilation Procedures NCT03066934 | Akdeniz University | — |
| Unknown | Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypercapnic COPD NCT03928535 | Xiangya Hospital of Central South University | N/A |
| Completed | Efficacy and Tolerance of High Flow Nasal Cannula for Respiratory Distress Syndrom in Late Preterms (34-36 Wee NCT02958488 | University Hospital, Montpellier | N/A |
| Completed | HFNC Flow Titration and Effort of Breathing in the PICU NCT02793674 | Children's Hospital Los Angeles | N/A |
| Completed | Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia NCT02943863 | Asan Medical Center | N/A |