| Not Yet Recruiting | LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients NCT07521488 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | The Study is a Randomised Clinical Trial (RCT) to Test if Preoperative Dental Screening is Superior to no Preo NCT07511673 | Region Skane | N/A |
| Not Yet Recruiting | Warfarin Effects on Male Fertility After Cardiac Surgery NCT07330869 | Città di Lecce Hospital, GVM Care & Research | — |
| Recruiting | Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease NCT07267117 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Recruiting | The TRICURE EU Pivotal Study NCT06581471 | TRiCares | N/A |
| Recruiting | Enhanced Valves Interventions and Safe AI Generated End Results NCT07213531 | Montreal Heart Institute | — |
| Completed | Validation of Naevia Medical in Valvulopathies NCT06392464 | Dilemma Solutions S.L. | — |
| Recruiting | CTSN Embolic Protection Trial NCT06027788 | Icahn School of Medicine at Mount Sinai | N/A |
| Withdrawn | Structural Heart and Valve Network PROSPECTIVE Registry NCT03928639 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Unknown | Safety and Performance of the Trialign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) NCT03225612 | Mitralign, Inc. | N/A |
| Terminated | High Dose Vitamin C in Cardiac Surgery Patients NCT02762331 | Virginia Commonwealth University | Phase 1 |
| Unknown | Effects of Hyperoxia on Open Heart Surgery NCT03012997 | Istanbul University | N/A |
| Completed | Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echoca NCT02867930 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 4 |
| Completed | Valve Leaflet Motion in Sutureless Bioprosthetic Aortic Valves NCT02671474 | Karolinska University Hospital | N/A |
| Unknown | Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Also Known as TriA NCT02574650 | Mitralign, Inc. | N/A |
| Unknown | Frailty and Cognitive Function Assessment of TAVI Patients NCT02650388 | Hungarian Institute of Cardiology | Phase 4 |
| Completed | Aortic Replacement Using Individualised Regenerative Allografts - ARISE (the "Surveillance") NCT02527629 | corlife | — |
| Withdrawn | Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS) NCT02515539 | Edwards Lifesciences | N/A |
| Completed | Magnetic Resonance Imaging and Fibrosis NCT02790008 | Linkoeping University | — |
| Terminated | A Clinical Study of the CardiAQ™ TMVI System (Transapical DS) NCT02478008 | Edwards Lifesciences | N/A |
| Unknown | The Pharmacogenetics of Optimal Warfarin Therapy in Chinese Patients After Heart Valve Replacement. NCT02710747 | Guangdong Provincial People's Hospital | Phase 4 |
| Completed | European Clinical Study for the Application of Regenerative Heart Valves - ESPOIR NCT02035540 | corlife | — |
| Completed | An Intervention to Reduce Delirium After Cardiac Surgery NCT02587039 | Johns Hopkins University | N/A |
| Unknown | The Study of Warfarin Maintenance Dose in Chinese Patients NCT01855737 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Recruiting | Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery NCT01653223 | Sun Yat-sen University | N/A |
| Completed | D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement NCT01996657 | Wuhan Asia Heart Hospital | — |
| Unknown | Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients NCT01610141 | Chinese PLA General Hospital | Phase 4 |
| Completed | CopenHeartVR - Integrated Rehabilitation of Patients After Heart Valve Surgery NCT01558765 | Rigshospitalet, Denmark | Phase 2 |
| Terminated | On-X Heart Valve - 17mm Aortic and 23mm Mitral NCT01812174 | On-X Life Technologies, Inc. | N/A |
| Completed | Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery NCT01384643 | Yonsei University | Phase 4 |
| Completed | Reinitiation of Anticoagulation After Temporary Withdrawal of Vitamin K Antagonist NCT01348074 | McMaster University | Phase 2 |
| Terminated | RiaSTAP vs. Conventional Transfusion in Patients Having Heart Valve Surgery NCT01283321 | Emory University | Phase 2 |
| Completed | Effect of Heart Valve Replacement on Cheyne-Stokes Respiration NCT01426776 | Nanjing Medical University | N/A |
| Completed | Effect of Simvastatin on Cardiac Function NCT01178710 | Sun Yat-sen University | N/A |
| Unknown | Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications NCT01000233 | Hospital Universitari Son Dureta | Phase 2 / Phase 3 |
| Completed | The Effects of Levosimendan on Haemodynamics in Patients Undergoing Elective Aortic Valve Replacement (AVR)Tog NCT01210976 | Tampere University Hospital | Phase 4 |
| Terminated | A Prospective Study With a New Device for the Monitoring of Cerebral Oxygenation on Cardiac Surgery Patients NCT00598936 | University of California, Irvine | — |
| Terminated | Using Beta Blockers to Treat Mitral Regurgitation NCT00700947 | Wake Forest University Health Sciences | Phase 1 |
| Completed | A Randomized Multicenter Clinical Study On the High Vacuum Body Cavity Drainage System Following Open Heart Su NCT00581399 | University of California, Irvine | Phase 2 |
| Completed | Randomized On-X Anticoagulation Trial NCT00291525 | On-X Life Technologies, Inc. | N/A |
| Withdrawn | ACTION - Anticoagulation Treatment Influence on Post-operative Patients NCT00187304 | Abbott Medical Devices | Phase 4 |
| Completed | Prospective Randomized On-X Versus SJM Evaluation Trial NCT00639782 | On-X Life Technologies, Inc. | N/A |
| Completed | Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacemen NCT01023152 | Yonsei University | N/A |