| Recruiting | Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine NCT06716489 | University of Sao Paulo | N/A |
| Not Yet Recruiting | Treatment Response to GON Pulsed Radiofrequency in Elderly Patients With Chronic Migraine NCT07363083 | Ankara City Hospital Bilkent | — |
| Not Yet Recruiting | Adolescent Lifestyle Medicine Headache Study NCT07373275 | MaineHealth | N/A |
| Enrolling By Invitation | App-based Breathing Program for Migraine Relief NCT07297901 | Arizona State University | N/A |
| Not Yet Recruiting | Prevalence and Determinants of Migraine Among Headache Patients NCT07038499 | Universiti Tunku Abdul Rahman | — |
| Recruiting | Migraines Accepted Laser Acupuncture Compared in Blood Test of MMP2 and CGRP NCT06584409 | Taichung Veterans General Hospital | N/A |
| Recruiting | Trial Designs for Evaluating Migraine Treatment NCT06617832 | University of Aarhus | N/A |
| Completed | Stellate Ganglion Blockade for Refractory Chronic Migraine NCT06891118 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients NCT06398353 | Chang Gung Memorial Hospital | N/A |
| Terminated | Intranasal Ketorolac Trial NCT06083571 | Washington University School of Medicine | Phase 2 |
| Completed | Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Question NCT04736654 | Gazi University | — |
| Withdrawn | Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache NCT04580238 | University of Alberta | Phase 1 |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) NCT06004388 | Click Therapeutics, Inc. | Phase 3 |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine NCT05853900 | Click Therapeutics, Inc. | N/A |
| Completed | Work-related Burden Changes, Quantified with HEADWORK, Among Individuals Treated with Migraine Preventive Ther NCT06812299 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification NCT06674772 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnair NCT04765501 | Gazi University | — |
| Completed | Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient NCT05658185 | University of Valencia | N/A |
| Active Not Recruiting | Ubrogepant treatmeNt in mIgraine Patients Utilizing mOnoclonal aNtibodies NCT05503082 | Chicago Headache Center & Research Institute | Phase 4 |
| Completed | The Effect of Two Different Massages on Migraine NCT05452330 | Biruni University | N/A |
| Unknown | Validating a Modified COMPASS 31questionnaire for Treatment Outcomes NCT05302479 | Brooke Army Medical Center | — |
| Unknown | Headache Inducing Effect of NN414 in Migraine Patients NCT04744129 | Danish Headache Center | N/A |
| Recruiting | Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption NCT05232942 | Hospital Clínico Universitario de Valladolid | — |
| Completed | Evaluating the Effectiveness of a Headache Management Program in Primary Care Settings NCT05067725 | Geisinger Clinic | N/A |
| Completed | Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain NCT05001399 | Billings Clinic | N/A |
| Completed | Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura NCT04905654 | Danish Headache Center | N/A |
| Unknown | Effects of a Multispecies Probiotic on Migraine NCT04696458 | Scripps Health | N/A |
| Recruiting | Mind Body Balance for Pediatric Migraine NCT04715685 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | The Effect of Adenosine on Cranial Hemodynamic, Headache and Migraine Induction Properties. NCT04577443 | Danish Headache Center | N/A |
| Unknown | Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in Humans NCT04232605 | Danish Headache Center | N/A |
| Completed | Adrenomedullin Effect on Migraine Without Patients NCT04111484 | Danish Headache Center | N/A |
| Unknown | Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea NCT04091789 | Pure Green | Phase 2 |
| Unknown | Study on Indomethacin-responsive Headaches NCT03967483 | Anne Ducros | — |
| Completed | The Effects of Maxipost (BMS 204352) on Cerebral Hemodynamic and Headache in Healthy Volunteers and Migraine P NCT03887325 | Danish Headache Center | N/A |
| Unknown | Effects of Aromatherapy on the Headache and Service Quality Among Nurses Working in Critical Care Nurses Units NCT03867864 | National Taiwan University Hospital | N/A |
| Unknown | The Prognosis of Migraine and Tension-Type Headache in Children and Adolescents NCT04623203 | Bnai Zion Medical Center | — |
| Completed | Using the S100B Protein for Emergency Headache Management Care (S100) NCT03490500 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | — |
| Unknown | Intravenous Paracetamol, Dexketoprofen and Ibuprofen in the Treatment of Acute Migraine Attack Headache NCT04372264 | Pamukkale University | Phase 4 |
| Unknown | Osteopathic Manipulative Treatment and Migraine Headaches NCT04976985 | St. Luke's Hospital, Pennsylvania | N/A |
| Completed | Mind and Body Approaches to Pain Reduction in Youth With Migraine NCT03472092 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Completed | The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA NCT03560024 | Danish Headache Center | N/A |
| Completed | Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine NCT03337620 | Tian Medical Inc. | Phase 3 |
| Completed | Muscle Tenderness and Hardness in Migraine Patients NCT03626805 | Danish Headache Center | — |
| Completed | Headache Inducing Effect of Cromakalim in Migraine Patients NCT03228355 | Danish Headache Center | N/A |
| Completed | Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pedi NCT03055767 | University of California, Irvine | Phase 2 |
| Completed | Interest of Auriculotherapy in Prophylaxis of Migraine and Headache in Patients With Migraines NCT03036761 | Hopital Foch | N/A |
| Completed | Carbon Monoxide Migraine-inducing Effects in Patients With Migraine Without Aura. NCT03075020 | Danish Headache Center | N/A |
| Unknown | Influence of Main Psychological and Social Factors on Primary Headaches NCT03577548 | Centre Hospitalier Universitaire de Besancon | — |
| Completed | Erenumab (AMG 334) Plus Combined Oral Contraceptive Drug Interaction Study in Healthy Females NCT02792517 | Amgen | Phase 1 |
| Completed | Short-term Effectiveness of Transcutaneous Nerve Stimulation in Reducing Migraine Related Pain NCT02438553 | Neurolief Ltd. | N/A |
| Completed | Adolescents With Migraine: What's Stress Got To Do With It? NCT02259387 | University of Colorado, Denver | — |
| Terminated | Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Dep NCT02972502 | OhioHealth | Phase 4 |
| Withdrawn | The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine NCT01653522 | The Cleveland Clinic | N/A |
| Terminated | Comparison of a Drug and Placebo in the Prevention of Migraine Headaches NCT01122381 | US Department of Veterans Affairs | Phase 1 / Phase 2 |
| Completed | EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model NCT00957983 | Danish Headache Center | Phase 1 / Phase 2 |
| Completed | Correlation of Calcitonin Gene-Related Peptide (CGRP) Levels in Saliva With the Evolution of an Attack of Migr NCT00772473 | Clinvest | — |
| Completed | An Italian Randomized Open-label Study of Occipital Nerve Stimulation in the Treatment of Chronic Migraine Hea NCT00407992 | IRCCS Sacro Cuore Don Calabria di Negrar | N/A |
| Completed | Study of Lornoxicam or Placebo for Acute Treatment of the Headache of Migraine. NCT00293657 | POZEN | Phase 2 |