Clinical Trials Directory

Trials / Unknown

UnknownNCT04232605

Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in Humans

Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon-like Peptide-1 in Healthy Volunteers and Migraine Patients

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
43 (estimated)
Sponsor
Danish Headache Center · Academic / Other
Sex
All
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

Studying glucagon-like peptide-1 (GLP-1) induced vasodilatory effects on extra - and intracerebral arteries and headache in healthy volunteers and migraine patients without aura.

Detailed description

The purpose of this study is to examine the association between vasodilation and intensity of headache triggered by glucagon-like peptide 1 (GLP-1) in healthy volunteers and migraine patients without aura.

Conditions

Interventions

TypeNameDescription
OTHERGLP-1 peptideReceive intravenous infusion of GLP-1. The dosage will be determined after a dose finding pilot study.
OTHERPlaceboReceive intravenous infusion saline

Timeline

Start date
2020-01-09
Primary completion
2021-12-31
Completion
2022-01-01
First posted
2020-01-18
Last updated
2020-01-18

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT04232605. Inclusion in this directory is not an endorsement.