| Recruiting | Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care NCT07089602 | BioLab Holdings | Phase 4 |
| Recruiting | Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers NCT06487780 | University of Southern California | N/A |
| Recruiting | Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard NCT06826339 | Tiger Biosciences, LLC. | Phase 4 |
| Active Not Recruiting | EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds NCT06640985 | ConvaTec Inc. | N/A |
| Recruiting | Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs NCT06600724 | MiMedx Group, Inc. | N/A |
| Completed | Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Kar NCT06358846 | SINA Health Education and Welfare Trust | N/A |
| Completed | Pressure Alternating Shoes NCT06026813 | University of Texas Southwestern Medical Center | N/A |
| Completed | Time to Heal (Wound, Healing, Dialogue, Nutrition) NCT06255288 | Hvidovre University Hospital | N/A |
| Completed | The Effect of Education on Patient Care Outcomes in Individuals With Diabetic Foot Ulcer NCT06753799 | Fadime Koyuncu | N/A |
| Terminated | Study to Determine the Feasibility of Using an At-home Foot Temperature Monitoring Device (Thermidas) NCT06032221 | NHS Greater Glasgow and Clyde | N/A |
| Completed | The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals NCT06023810 | Okan University | N/A |
| Active Not Recruiting | Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers NCT05586542 | Vitruvian Medical Devices, Inc. | Phase 1 |
| Recruiting | Flexor Tenotomy and Ulcer Recurrence NCT05228340 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Comparison of the Quality of Life and the Level of Precarity of a Diabetic Population With and Without Foot Ul NCT05165758 | University Hospital Center of Martinique | — |
| Unknown | Use of Procenta® Conformable Barrier for Non-Healing Foot & Ankle Ulcers in Patients With Diabetes Mellitus Ty NCT05099887 | The VA Western New York Healthcare System | N/A |
| Recruiting | Total Contact Soft Cast in Diabetic Foot Ulcers NCT04210089 | University of Minnesota | N/A |
| Unknown | Approaches to Foot Complication Prevention: A Survey of Diabetes Educators NCT04400344 | Podimetrics, Inc. | — |
| Completed | Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population NCT04327622 | LMC Diabetes & Endocrinology Ltd. | — |
| Terminated | Prevention of Primary Foot Ulcers in High-risk Diabetes Patients NCT03958539 | Countess of Chester NHS Foundation Trust | N/A |
| Unknown | Study of Combined Topical Growth Factor and Protease Inhibitor in Chronic Wound Healing NCT02845466 | McMaster University | Phase 3 |
| Completed | Assessing the Effects of ELO Water on Diabetic Foot Ulcers NCT05908968 | Changi General Hospital | N/A |
| Recruiting | Diabetic Foot Ulcer Imaging- Study 2 NCT03942081 | Linnea Polgreen | N/A |
| Completed | Reliability of a Diabetic Foot Ulcer Risk Stratification and Referral Algorithm NCT03370237 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Terminated | Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers NCT02563522 | Helixmith Co., Ltd. | Phase 3 |
| Completed | Evaluation of The Effectiveness of m-DAKBAS on Foot Care NCT04029103 | Sanko University | N/A |
| Completed | Micro-mobile Foot Compression and Diabetic Foot NCT03135535 | Baylor College of Medicine | Phase 2 |
| Completed | Impact of Remote Foot Temperature Monitoring NCT04345016 | Kaiser Permanente | N/A |
| Unknown | Efficacy and Safety Evaluation of the Intralesional Recombinant Human Epidermal Growth Factor (rhEGF) in Subje NCT02554851 | The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) | Phase 3 |
| Unknown | Mesenchymal Stromal Cell Derivatives in the Treatment of Chronic Diabetic Foot Ulcers Type 1 and 2 NCT02943486 | Universidad Autónoma de Bucaramanga | Phase 1 / Phase 2 |
| Unknown | Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers NCT02838784 | Tides Medical | N/A |
| Withdrawn | Use of Santyl Within an Accountable Care Organization NCT02716519 | Smith & Nephew, Inc. | Phase 4 |
| Completed | GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers NCT02675855 | Osiris Therapeutics | Phase 4 |
| Completed | Use of Santyl in Diabetic Foot Ulcers NCT02581488 | Smith & Nephew, Inc. | Phase 4 |
| Completed | Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers NCT02501538 | University of Texas Southwestern Medical Center | N/A |
| Completed | Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers NCT02447172 | Innocoll | Phase 3 |
| Completed | Evaluation of Pressure Distribution of Kyboot Shoes in Comparison to Other Foot Wear NCT02451722 | Sheba Medical Center | N/A |
| Completed | Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers NCT02427802 | Innocoll | Phase 3 |
| Unknown | Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers NCT02399826 | Lower Extremity Institute for Research and Therapy | N/A |
| Completed | NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers NCT02461641 | NuTech Medical, Inc | N/A |
| Completed | APT001 Plasma/NO Generator to Treat Diabetic Foot Ulcer in Adults NCT02356835 | Origin Inc. | N/A |
| Withdrawn | Negative Pressure Wound Therapy as a Drug Delivery System (ADANPWT) NCT02308800 | University of Texas Southwestern Medical Center | N/A |
| Completed | Evaluation of Fluorescence-image Guided Wound Assessment vs. Standard Practice NCT02315092 | University Health Network, Toronto | — |
| Completed | The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) NCT02334241 | INRESA Pharma | N/A |
| Terminated | NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers NCT02166294 | Amniox Medical, Inc. | N/A |
| Completed | In-Home Assessment of a Smart Foot Mat for Prevention of Diabetic Foot Ulcers NCT02647346 | Podimetrics, Inc. | N/A |
| Completed | Evaluation of a New Device "Orthèse Diabète" in the Healing of Foot Ulcers in Diabetic Patients NCT01956162 | Proteor Group | N/A |
| Terminated | A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers NCT01858545 | Integra LifeSciences Corporation | N/A |
| Terminated | ECM and Blood Components for Wound Healing NCT01909908 | Cook Group Incorporated | N/A |
| Terminated | Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix NCT01729286 | Integra LifeSciences Corporation | N/A |
| Terminated | The Relationship of Hemoglobin A1c and Diabetic Wound Healing NCT01350102 | Susan Hassenbein | Phase 4 |
| Completed | Treatment Study of Negative Pressure Wound Therapy for Diabetic Foot Wounds NCT01480362 | University of Witten/Herdecke | N/A |
| Completed | Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design NCT01699100 | Taichung Veterans General Hospital | N/A |
| Terminated | A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers NCT01270633 | Integra LifeSciences Corporation | N/A |
| Terminated | A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Fo NCT01013792 | Solventum US LLC | N/A |
| Completed | Effects of N-acetylcysteine on Diabetic Foot Oxygenation NCT01082445 | University of Turin, Italy | Phase 3 |
| Completed | Prevention of Secondary Foot Ulcers in Patients With Diabetes Using Systematic Measuring of Skin Temperature. NCT01269502 | Oslo University Hospital | N/A |
| Completed | Safety and Efficacy Study of DSC127 in Treating Subjects With Diabetic Ulcers NCT00796744 | US Biotest, Inc. | Phase 2 |
| Completed | Evaluation of a Medical Food for Chronic Wounds NCT00711217 | Abbott Nutrition | Phase 3 |
| Withdrawn | The Use of Bioscaffolds in Conjunction With Negative Pressure Therapy: A Prospective Randomized Double-Blinded NCT01228500 | Integra LifeSciences Corporation | N/A |
| Completed | Dynamic Plantar Microvascular Skin Response to Compressive Loads in At-risk Diabetic and Healthy Control: a Pi NCT01580917 | Temple University | — |
| Completed | Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot In NCT00516958 | Oculus Innovative Sciences, Inc. | Phase 2 |
| Completed | Clinical Trial to Evaluate the Efficacy and Safety of Sodium Bemiparin for Treatment of Diabetic Foot Ulcers NCT00448903 | Rovi Pharmaceuticals Laboratories | Phase 3 |
| Terminated | Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot U NCT00318214 | Pfizer | Phase 2 |
| Completed | A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of NCT00351767 | Genentech, Inc. | Phase 2 |
| Completed | Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers NCT00312364 | Pfizer | Phase 2 |
| Terminated | Efficacy of a Low-Molecular-Weight Heparin (Bemiparin) in the Treatment of Chronic Foot Ulcers in Diabetic Pat NCT00399425 | Spanish National Health System | Phase 2 / Phase 3 |