| Recruiting | Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis NCT06392971 | First Affiliated Hospital of Chengdu Medical College | Phase 2 |
| Unknown | A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis NCT05604261 | Xuanzhu Biopharmaceutical Co., Ltd. | Phase 2 |
| Completed | Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing Gum NCT05129670 | Reckitt Benckiser Healthcare (UK) Limited | N/A |
| Terminated | Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years NCT04821310 | Pfizer | Phase 2 |
| Unknown | The Effect of Physiotherapy on Post POEM Reflux NCT05326113 | Institute for Clinical and Experimental Medicine | N/A |
| Unknown | Twenty Four Hour Ambulatory pH & Impedance Testing: Normative Data for Indian Population NCT05004155 | Asian Institute of Gastroenterology, India | — |
| Recruiting | Esophagus-sparing Radiotherapy for Metastatic Spinal Cord Compression. NCT05109819 | Herlev Hospital | N/A |
| Unknown | Study of Dietary Patterns and Food Diversity in Russian GERD Patients NCT04252144 | Russian Academy of Medical Sciences | N/A |
| Terminated | Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung C NCT04225026 | Galera Therapeutics, Inc. | Phase 2 |
| Enrolling By Invitation | The Johns Hopkins Heartburn Center Registry NCT03853772 | Johns Hopkins University | — |
| Unknown | Management of Esophagitis Following Repair of Esophageal Atresia NCT03619408 | Boston Children's Hospital | — |
| Unknown | The Bacterial Composition of the Stomach in Reflux Disease NCT03835663 | Imperial College London | — |
| Completed | Sensory Evaluation of Oral Nutrition Supplements in Patients at Risk for Mucositis Undergoing Cancer Treatment NCT03228147 | Rutgers, The State University of New Jersey | N/A |
| Unknown | Study of Epigallocatechin-3-gallate (EGCG) for Esophagus Protection in Patients With Lung Cancer Receiving Rad NCT02577393 | Shandong Cancer Hospital and Institute | Phase 2 |
| Completed | Esophageal Cytology With FISH in Detecting Esophageal Cancer NCT02100189 | OHSU Knight Cancer Institute | N/A |
| Withdrawn | CYP2C19 Genotype Predictor of Gastric Acid Suppression NCT01824199 | Mayo Clinic | EARLY_Phase 1 |
| Completed | The Role of HIF-2a in the Pathogenesis of Reflux Esophagitis NCT01733810 | Dallas VA Medical Center | N/A |
| Recruiting | Domperidone in Treating Patients With Gastrointestinal Disorders NCT01696734 | M.D. Anderson Cancer Center | Phase 3 |
| Completed | Esophageal Monitoring Device for Assessing Mucosal Impedance NCT01556919 | Vanderbilt University | — |
| Completed | Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy F NCT01262560 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Eosinophilic Esophagitis Databank NCT01323803 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Terminated | The Effects of Whole Food Intervention on Mucositis in Patients Treated for Thoracic Cancer NCT02575391 | Providence Health & Services | Phase 1 / Phase 2 |
| Completed | Evaluation Study of a Management Strategy for Gastroesophageal Reflux Disease (GERD) NCT00842387 | AstraZeneca | — |
| Terminated | Domperidone for Relief of Gastrointestinal Disorders NCT00761254 | Carle Physician Group | N/A |
| Completed | Off Label Use of Infliximab in Adult Patients With Severe Eosinophilic Esophagitis NCT00523354 | Swiss EE Study Group | Phase 2 |
| Completed | Safety and Efficacy of Ilaprazole 5, 20 and 40 mg QD and Lansoprazole 30 mg QD on Healing of Erosive Esophagit NCT00471094 | Takeda | Phase 2 |
| Completed | Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain NCT00677378 | Medical College of Wisconsin | — |
| Completed | Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers NCT00284908 | STEBA France | Phase 1 |
| Unknown | The Effect of Nexium on Transmucosal Esophageal Leak NCT00216788 | Main Line Health | Phase 1 |
| Completed | Prospective Analysis of Eosinophilic Esophagitis in Patients Presenting With Dysphagia NCT00256529 | University of Utah | — |
| Completed | A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab NCT00123630 | University of Utah | Phase 2 |
| Completed | Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis NCT00195208 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Study to Identify Non-Invasive Markers of Gastrointestinal Allergy NCT00272818 | Boston Children's Hospital | — |
| Completed | Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis NCT00123656 | University of Utah | Phase 2 |
| Completed | Risk of Cancer Among Pantoprazole Users NCT01322633 | Pfizer | — |
| Completed | Intravenous (IV) Pantoprazole in Erosive Esophagitis NCT00133770 | Emory University | Phase 4 |
| Completed | Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule NCT00579410 | VA Office of Research and Development | — |
| Completed | Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis i NCT00081315 | MedImmune LLC | Phase 2 |
| Completed | Intravenous vs Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis NCT00175045 | Takeda | Phase 2 |
| Completed | Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD) NCT00872755 | G. Hatzikosta General Hospital | Phase 4 |