NCT01323803

Eosinophilic Esophagitis Databank

Eosinophilic Esophagitis (EoE) Databank (CoFAR 5)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 709 (actual)
• Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) · NIH
• Sex: All
• Age: 6 Months – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will establish a registry for participants with eosinophilic esophagitis (EoE) and create a research resource that will provide further insights into EoE.

Detailed description

Eosinophilic esophagitis (EoE) is a newly recognized chronic disease that is increasingly being diagnosed in children and adults. Many patients with EoE also have food allergies. EoE is characterized by inflammation and accumulation of a specific type of immune cell, called an eosinophil, in the esophagus. While there have been several large studies of EoE, very few have focused on the roles the immune system, genetics/heredity, and the environment in EoE. The samples and information collected from participants will help to identify and understand the genetic mechanisms underlying eosinophilic esophagitis. The Cincinnati Children's Hospital Medical Center will serve as the Central Laboratory for genetic characterization studies.

Conditions

• Esophagitis
• Eosinophilic Esophagitis

Timeline

• Start date: 2011-04-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2011-03-28
• Last updated: 2017-08-28

Locations

5 sites across 1 country: United States