Clinical Trials Directory

Trials / Completed

CompletedNCT00081315

Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Phase II, Randomized, Double-Blind, Multicenter Trial of Subcutaneous Amifostine (Ethyol®) Versus Placebo in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
130 (planned)
Sponsor
MedImmune LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to assess the activity of subcutaneous (SC) amifostine on the incidence and severity of acute radiochemotherapy-induced esophagitis in patients with unresectable Stage IIIA or IIIB non-small cell lung cancer (NSCLC) receiving combined modality therapy.

Conditions

Interventions

TypeNameDescription
DRUGAmifostine

Timeline

Start date
2003-11-01
Completion
2006-08-01
First posted
2004-04-09
Last updated
2007-08-21

Locations

24 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00081315. Inclusion in this directory is not an endorsement.