| Recruiting | Effects of Glycemic Control and Clinical Parameters on Tibial Nerve Conduction Latency in Diabetic Peripheral NCT07525882 | Fenerbahce University | — |
| Recruiting | Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Periphe NCT07380880 | Montiha Azeem | N/A |
| Not Yet Recruiting | Effect of an Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy NCT07075367 | Federal University of Piaui | N/A |
| Recruiting | New Diagnostic Tool (MinION) for Identifying Microorganisms in Foot Wounds of Patients Living With Diabetic Fo NCT07391995 | Centre Hospitalier Universitaire de Nīmes | — |
| Not Yet Recruiting | Exercise Effects on Pain, Sleep and Depression in Diabetic Peripheral Neuropathy NCT07291596 | Amasya University | N/A |
| Not Yet Recruiting | Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic NCT07260656 | Carilion Clinic | EARLY_Phase 1 |
| Not Yet Recruiting | Effect of Hydrotherapy On Pain, Balance and Quality of Life in Patients With Diabetic Peripheral Neuropathy NCT07260214 | Beni-Suef University | N/A |
| Recruiting | Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral N NCT06591780 | Florida Institute for Human and Machine Cognition | N/A |
| Not Yet Recruiting | Effect of an Exercise Program on Motor Dysfunctions Caused by Diabetic Peripheral Neuropathy NCT07100301 | Federal University of Piaui | N/A |
| Not Yet Recruiting | Low Level Laser VS Transcutaneous Vagus Nerve Stimulation on Vascular Changes in Patients With Diabetic Polyne NCT07078058 | Horus University | N/A |
| Recruiting | Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy NCT07036796 | Ain Shams University | Phase 2 |
| Recruiting | Levagen+ Efficacy Study on Diabetic Peripheral Neuropathy NCT07028528 | RDC Clinical Pty Ltd | Phase 2 |
| Active Not Recruiting | The Effect of Hand and Foot Exercises Combined With Cold Application or Virtual Reality on Diabetic Neuropathy NCT07085130 | Sakarya University | N/A |
| Not Yet Recruiting | Effect of Sensory Training on Functional Performance, Balance, Gait in Type 2 Diabetic Individuals With Neurop NCT06979401 | Aylin DEMİR | N/A |
| Recruiting | Cross-cultural Adaptation and Validity of the Arabic-translated NEUROPATHY-SPECIFIC QUALITY OF LIFE Questionna NCT06483620 | Cairo University | — |
| Not Yet Recruiting | The Effect of Piracetam on Diabetic Peripheral Neuropathy Patients NCT06479629 | Ain Shams University | Phase 4 |
| Active Not Recruiting | A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes an NCT06797869 | Novo Nordisk A/S | Phase 2 |
| Recruiting | Walking Function in Diabetic Peripheral Neuropathy NCT05965336 | Florida Institute for Human and Machine Cognition | N/A |
| Not Yet Recruiting | Intraneural Facilitation Therapy and Nerve Flossing Technique in Patients With Diabetic Peripheral Neuropathy NCT06663670 | Riphah International University | N/A |
| Recruiting | Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy NCT07274735 | Riphah International University | N/A |
| Active Not Recruiting | Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT Study NCT06330233 | Zhejiang Chinese Medical University | N/A |
| Completed | Effects of Virtual Reality-Based Balance Training Compared to Conventional Balance Training to Reduce Risk of NCT06740227 | Foundation University Islamabad | N/A |
| Completed | A Pilot Study of the Effectiveness of Foot-Ankle and Walking Exercises in Patients With Diabetes Mellitus NCT07270328 | Taipei Medical University | N/A |
| Not Yet Recruiting | Needle-Free Subcutaneous Injector and Conventional Intramuscular Injection of Mecobalamin in Diabetes Peripher NCT06400888 | Peking University Third Hospital | N/A |
| Completed | Effect Whole Body Vibration on Balance in Post Diabetic Menopause Women NCT06937008 | Cairo University | N/A |
| Recruiting | Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy NCT06287736 | Ohio State University | N/A |
| Completed | Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients with and Without Polyneuropathy NCT06033508 | Pamukkale University | N/A |
| Completed | Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy. NCT06303453 | Riphah International University | N/A |
| Unknown | Effect of Structured Training Program in Diabetic Patients NCT06262074 | Maharishi Markendeswar University (Deemed to be University) | N/A |
| Recruiting | Comparative Effects of Propioceptive Neuromascular Facilitation and Neural Flossing in Diabetic Neuropathy NCT06397209 | Riphah International University | N/A |
| Recruiting | Muscle and Bone in Patients with Diabetes Mellitus and Neuropathy NCT06519942 | University Hospital, Ghent | — |
| Completed | Effects of Multisystem Exercise on Balance, Postural Stability, Mobility and Pain in Patients With DPN. NCT06130917 | Riphah International University | N/A |
| Completed | A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain NCT06074562 | Eli Lilly and Company | Phase 2 |
| Recruiting | Balance Control and Recovery in Diabetes Peripheral Neuropathy NCT06544876 | Lisa Griffin | N/A |
| Active Not Recruiting | Neuromuscular Electrical Stimulation For The Treatment of Diabetic Neuropathy NCT03767478 | Imperial College London | N/A |
| Unknown | Early Warning of Diabetic Peripheral Neuropathy by Using Infrared Thermography and the Effectiveness of Electr NCT06074913 | Zhejiang Chinese Medical University | N/A |
| Completed | Ankle Proprioceptive Training In Patients With Diabetic Peripheral Neuropathy NCT05848180 | Riphah International University | N/A |
| Unknown | A Novel Non-Pharmacological Treatment of Diabetic Neuropathy NCT05414968 | Auburn University | N/A |
| Terminated | Immunonutrition for Diabetic Foot Ulcers NCT05281562 | Prisma Health-Midlands | Phase 2 / Phase 3 |
| Completed | Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study NCT05993871 | Tanta University | — |
| Completed | Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN) NCT05660538 | Vertex Pharmaceuticals Incorporated | Phase 2 |
| Completed | Whole-Body Vibration Versus Kineso Tape on Nerve Conduction in Patient With Diabetic Peripheral Neuropathy NCT06579716 | Cairo University | N/A |
| Completed | Effects of Vibration Therapy in Addition to Routine Physical Therapy in Patients With Diabetic Neuropathy NCT05580705 | University of Lahore | N/A |
| Unknown | Laser Acupuncture on Diabetes-induced Peripheral Neuropathy NCT05921019 | Taiwan Municipal An-Nan Hospital-China Medical University | N/A |
| Unknown | Effect of Non-invasive Vagus Nerve Stimulation on Cognitive Functions in Diabetic Polyneuropathy Patients NCT06048653 | heba ahmed khalifa | N/A |
| Withdrawn | Exercise Induced Hypoalgesia Diabetes NCT05296642 | University of Miami | N/A |
| Completed | DEXINEURO® Tab on Blood Glucose Reduction in Patients With Type 2 Diabetes Accompanied by Diabetic Peripheral NCT06191614 | Hanlim Pharm. Co., Ltd. | — |
| Completed | Diabetes, Falls, and Fractures NCT05389566 | Aalborg University Hospital | — |
| Unknown | Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy NCT05162690 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 2 / Phase 3 |
| Completed | Monitoring Physiologic Parameters in Individuals With Diabetic Peripheral Neuropathy NCT05613556 | Orpyx Medical Technologies Inc. | — |
| Completed | Alter-G Training on Gait and Balance in Diabetic Neuropathy Patients NCT05565924 | Umm Al-Qura University | N/A |
| Unknown | Microvascular Dysfunction in Diabetic Peripheral Neuropathy NCT05118217 | University of Plymouth | — |
| Recruiting | Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy NCT05521737 | Instituto Mexicano del Seguro Social | N/A |
| Unknown | Clinical Study of Acupuncture in the Treatment of Diabetic Peripheral Neuropathy NCT05863793 | Shanghai University of Traditional Chinese Medicine | N/A |
| Withdrawn | Peripheral Nerve Responses to Focal Vibration and Implications in Pain and Mobility for Patients With Diabetic NCT05041816 | University of Oklahoma | N/A |
| Completed | Corneal Nerves Function and Structure NCT04222660 | VA Office of Research and Development | N/A |
| Completed | A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Ne NCT04873232 | Helixmith Co., Ltd. | Phase 3 |
| Completed | Pregabalin and Alpha-lipoic Acid Combination Versus Each Monotherapy in Patients With Diabetic Peripheral Neur NCT04846673 | Yuhan Corporation | Phase 4 |
| Recruiting | Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy NCT04658693 | VA Office of Research and Development | N/A |
| Completed | Effects of Virtual Reality-based Balance Training on Balance of Diabetic Peripheral Neuropathy Patients NCT05258240 | Riphah International University | N/A |
| Unknown | Exploratory Study of the Efficacy of Standard of Care Revascularization of the Lower Extremity NCT04720170 | Diabetes and Glandular Disease Clinic | N/A |
| Completed | Sensorimotor Training and Gait in Diabetic Polyneuropathy NCT04543032 | Cairo University | N/A |
| Completed | Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic Pain NCT04688671 | Eliem Therapeutics (UK) Ltd. | Phase 2 |
| Completed | Effect of Vitamin D in Patients With Diabetic Peripheral Neuropathy to Alleviate Pain and Improvement of Sympt NCT04984044 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | N/A |
| Unknown | Effect of High Tone External Muscle Stimulation on Peripheral Arterial Disease NCT04555876 | Cairo University | N/A |
| Unknown | LiuWeiLuoBi Granule for the Treatment of Diabetic Peripheral Neuropathy NCT04457531 | China Academy of Chinese Medical Sciences | EARLY_Phase 1 |
| Completed | Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain NCT04455633 | Lexicon Pharmaceuticals | Phase 2 |
| Unknown | Diagnostic Accuracy of Quantitative Neuropad Test for Diabetic Peripheral Neuropathy NCT05347420 | First Affiliated Hospital of Chongqing Medical University | — |
| Unknown | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of SYHA1402 in Healthy Subject NCT04453618 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Phase 1 |
| Unknown | BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome NCT04408261 | Dongzhimen Hospital, Beijing | Phase 2 |
| Completed | Strength And Balance Training on Diabetic Peripheral Neuropathy NCT04807452 | Riphah International University | N/A |
| Completed | Implementation of Telemedicine for Patient With Lower Extremity Wounds NCT04440839 | University of California, Davis | N/A |
| Unknown | Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedbac NCT04217005 | ETH Zurich | N/A |
| Unknown | Effect of Circulating lncRNAs on Type 2 Diabetic Peripheral Neuropathy NCT04638556 | Jinshan Hospital Fudan University | — |
| Unknown | Treatment for Foot Pain Caused by Diabetic Neuropathy Using Recurrent TransCutaneous Magnetic Stimulation (TCM NCT04000867 | ZyGood LLC | N/A |
| Unknown | Effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy NCT03983200 | Majianhua | N/A |
| Terminated | An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain NCT04006392 | Erchonia Corporation | N/A |
| Completed | Green Tea Extracts for Mild-to-moderate Diabetic Peripheral Neuropathy NCT04543422 | Egyptian Biomedical Research Network | N/A |
| Recruiting | Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD) NCT04257877 | Aristotle University Of Thessaloniki | — |
| Completed | Foot and Ankle Mobilisation in Diabetic Peripheral Neuropathy NCT03195855 | University of Plymouth | N/A |
| Completed | Pharmacokinetics of Two Formulation of Pregabalin NCT03712475 | Yung Shin Pharm. Ind. Co., Ltd. | Phase 4 |
| Unknown | The Role of a Clinical Pharmacist in Lifestyle Modification in Type 2 Diabetic Patients With Peripheral Neurop NCT03356041 | Hawler Medical University | N/A |
| Completed | Titration Study of ABX-1431 NCT03447756 | Abide Therapeutics | Phase 1 |
| Completed | Resistance Training in Patients With Diabetic Neuropathy NCT03252132 | Danish Pain Research Center | N/A |
| Completed | Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropat NCT03219320 | Aptinyx | Phase 2 |
| Completed | Effectiveness of Exercises in Patient With Diabetic Peripheral Neuropathy NCT03450200 | Okayama University | N/A |
| Completed | Neuropathic Pain in Elderly People With Diabetes: Impact on Quality of Life and Cognition NCT03909841 | Queen Elizabeth Hospital, Hong Kong | — |
| Completed | Efficacy of Platelet Rich Plasma Injection in Diabetic Neuropathy NCT03250403 | Assiut University | N/A |
| Completed | Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathy NCT02728687 | University of British Columbia | Phase 1 / Phase 2 |
| Completed | Impact of Therapeutic Footwear and Plantar Orthoses on Diabetic Neuropathic Foot in Quality of Life and Functi NCT04605900 | Universidade do Algarve | N/A |
| Completed | Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy NCT03077893 | Regenesis Biomedical, Inc. | N/A |
| Completed | Polyneuropathy in Diabetes Mellitus Type 2 NCT02947828 | Danish Pain Research Center | — |
| Completed | Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain NCT02461225 | Erchonia Corporation | N/A |
| Completed | Aerobic Training in Post-MI Patients With DPN NCT03913793 | Yousra Hisham Abdel Fattah | N/A |
| Completed | Group Acupuncture Treatment Effects for Painful Diabetic Neuropathy (GATE-PDN) NCT02104466 | University of California, San Francisco | N/A |
| Withdrawn | Laser Therapy for Diabetic Peripheral Neuropathic Pain NCT02328911 | University of Miami | Phase 2 |
| Completed | 12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Cont NCT02332005 | NeuromaxBionevia | Phase 2 / Phase 3 |
| Completed | Electrical Stimulation for Improving Balance in Diabetes NCT02337218 | University of Texas Southwestern Medical Center | N/A |
| Completed | Balancing Treatment Outcomes and Medication Burden Among Patients With Symptomatic Diabetic Peripheral Neuropa NCT02056431 | Kaiser Permanente | N/A |
| Completed | Effect Of Mesenchymal Stem Cells Transfusion on the Diabetic Peripheral Neuropathy Patients . NCT02387749 | Cairo University | N/A |
| Unknown | A Study of Xuebi Formula for Diabetic Peripheral Neuropathy(Qi-deficiency and Blood-stasis) NCT02039544 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | N/A |
| Unknown | The Nutritional Benefits of Metanx in Patients With Diabetic Peripheral Neuropathy (MEDIAN) NCT01990092 | Pamlab, Inc. | N/A |
| Completed | Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Diabetic Peripheral Neuropathy NCT01893125 | Convergence Pharmaceuticals | Phase 2 |
| Unknown | Objective Measures of Nerve Integrity, Posture, Gait and Blood Flow, After Nerve Decompression NCT01735903 | Foot Surgery Center of Northern Colorado | — |
| Completed | Safety and Efficacy of CBX129801 in Patients With Type 1 Diabetes NCT01681290 | Cebix Incorporated | Phase 2 |
| Terminated | MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain NCT01620775 | University of Michigan | N/A |
| Completed | The Effect of Mindfulness Based Stress Reduction in Patients With Painful Diabetic Peripheral Neuropathy NCT02127762 | Ottawa Hospital Research Institute | N/A |
| Completed | Ultrasonographic Evaluation of Diabetic Neuropathy NCT02308059 | Cukurova University | — |
| Completed | A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Com NCT01533428 | Astellas Pharma Inc | Phase 3 |
| Unknown | The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy NCT06041412 | First Affiliated Hospital of Wenzhou Medical University | — |
| Unknown | The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy NCT06041399 | First Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Completed | Asian Phase 2 Study for Treatment of Pain Associated With Diabetic Peripheral Neuropathy NCT01504412 | Daiichi Sankyo Co., Ltd. | Phase 2 |
| Completed | Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective S NCT01512030 | Landeskrankenhaus Feldkirch | — |
| Completed | Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy NCT01496365 | Daiichi Sankyo | Phase 2 |
| Completed | Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripher NCT01474772 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | Safety Study of Intranasal Insulin in Type 1 Diabetes and Diabetic Peripheral Neuropathy NCT01469559 | University of Calgary | Phase 2 |
| Completed | The Effect of Pregabalin on Pain Related to Walking in Patients With Diabetic Peripheral Neuropathy NCT02927951 | Eastern Virginia Medical School | Phase 3 |
| Completed | In Vivo Corneal Confocal Microscopy for Non-invasive Assessment of Diabetic Peripheral Neuropathy NCT01695629 | University of Michigan | — |
| Unknown | Metanx® P.L.U.S. Program (Progress Through Learning, Understanding & Support) NCT01368549 | Pamlab, L.L.C. | — |
| Terminated | A Study Of The Analgesic (Pain-Relief) Effects Of Tanezumab In Adult Patients With Diabetic Peripheral Neuropa NCT01087203 | Pfizer | Phase 2 |
| Withdrawn | Neuragen for Peripheral Diabetic Neuropathy NCT00861952 | The Canadian College of Naturopathic Medicine | Phase 3 |
| Completed | A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients NCT01041859 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy NCT01086150 | Albany Medical College | Phase 2 / Phase 3 |
| Completed | Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral Neuropathy NCT00891683 | Aegera Therapeutics | Phase 2 |
| Completed | Diffusion Tensor Imaging of Sural Nerves in Diabetic Peripheral Neuropathy NCT00835757 | University of Michigan | — |
| Completed | Fall Risk Assessment in People With Diabetic Neuropathy NCT01040962 | Stephen D. Jernigan, PT, PhD | — |
| Completed | Evaluation of Exenatide in Patients With Diabetic Neuropathy NCT00855439 | University of Michigan | N/A |
| Unknown | Double Blind RCT of Bicifadine SR in Outpatients With Chronic Neuropathic Pain Associated With Diabetes NCT00553592 | XTL Biopharmaceuticals | Phase 2 |
| Completed | IMX-150 Cream for Diabetic Neuropathy NCT00641953 | Procris Pharmaceuticals | Phase 2 |
| Completed | A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Periphera NCT00476151 | EpiCept Corporation | Phase 2 |
| Completed | Validation Study of Neuropathic Pain NCT00623961 | University of Wisconsin, Madison | — |
| Completed | Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx® NCT00933998 | Carolina Musculoskeletal Institute | N/A |
| Completed | Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study NCT00614341 | MedRelief | Phase 4 |
| Completed | Safety and Efficacy of Gabapentin in Diabetic Peripheral Neuropathy NCT00712439 | Depomed | Phase 2 |
| Completed | Safety of Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy NCT00159731 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |