NCT06033508

Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients with and Without Polyneuropathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Pamukkale University · Academic / Other
• Sex: All
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to show how whole body vibration training practiced for 12 weeks affects the levels of inflammatory biomarkers such as C reactive protein (CRP) and, interleukin-6 (IL-6), in Type 2 diabetic patients (T2DM) with and without peripheral neuropathy.

Detailed description

Volunteers with type 2 diabetes mellitus with and without peripheric neuropathy will be evaluated in terms of any contra-indication that will restrain them from making exercise with whole body vibration device. 60 male or female volunteers who are suitable in terms of inclusion/exclusion criteria will be invited for the study. Volunteers will be randomly distributed to one of the 3 groups. Each group will contain 20 participants. 1st group will include type 2 diabetic patients with peripheric neuropathy and 2nd and 3rd groups will include type 2 diabetic patients without neuropathy. Patients in group 1 and 2 will make static isometric exercises on vibration platform whereas patients in group 3 will make the same exercises on land in the hospital setting. Participants will be requested to complete 3 months of exercise. They will be evaluated before and at the end of the 3 months of exercise with physical measures such as waist and hip circumference, 6-minute walk test, body composition measured by bioimpedance, muscle thickness, and blood tests to measure inflammatory biomarkers.

Conditions

• Type 2 Diabetes
• Diabetic Peripheral Neuropathy
• Exercise

Interventions

Type	Name	Description
OTHER	exercise with whole body vibration device	exercise with whole body vibration device
OTHER	placebo exercise	exercise without vibration on land

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-11-01
• Completion: 2024-11-01
• First posted: 2023-09-13
• Last updated: 2025-02-06

Locations

1 site across 1 country: Turkey (Türkiye)