| Not Yet Recruiting | Irisin Hormone as a Novel Diagnostic Marker for Detection and Progression of Diabetic Nephrophathy Patients NCT07435480 | Sohag University | — |
| Recruiting | Formoterol in Diabetes NCT07022418 | Medical University of South Carolina | Phase 2 |
| Recruiting | Transformative Research in Diabetic Nephropathy 2.0 NCT07444203 | University of Pennsylvania | — |
| Recruiting | ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases NCT07187713 | Ace Cells Lab Limited | Phase 4 |
| Not Yet Recruiting | Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis NCT07010250 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With D NCT06846034 | Poitiers University Hospital | N/A |
| Not Yet Recruiting | Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose- NCT06147232 | Steno Diabetes Center Copenhagen | Phase 2 |
| Recruiting | Nutritional Outcomes of Lotus Seed (Nelumbo Nucifera) on Diabetic Sensorimotor Polyneuropathy NCT06778018 | Riphah International University | N/A |
| Completed | Effect of High-intensity Laser Exercise Versus Moderate-intensity Aerobic Exercise on Diabetic Polyneuropathy NCT06884462 | Deraya University | N/A |
| Recruiting | Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease NCT06217302 | Alessandro Doria | Phase 3 |
| Not Yet Recruiting | Assessment of the Association Between Visceral Obesity and the Progression of Diabetic Nephropathy NCT06563791 | Assiut University | — |
| Recruiting | Clinical Outcome of Vinpocetine in Diabetic Nephropathy NCT06441591 | Ain Shams University | Phase 2 / Phase 3 |
| Recruiting | Study of WAL0921 in Patients With Glomerular Kidney Diseases NCT06466135 | Walden Biosciences | Phase 2 |
| Completed | Serum Uromodulin and DN Systematic Review and Meta Analysis NCT06596863 | Tanta University | — |
| Completed | Perfenidone in Type 2 Diabetic Patients With Diabetic Neuropathy NCT06224790 | Sidrah Lodhi | Phase 4 |
| Completed | Effect of High Intensity Interval Versus Moderate Intensity Continuous Training on Microalbuminurea NCT06616805 | Cairo University | N/A |
| Unknown | Henagliflozin Delays the Progress of Diabetic Nephropathy Via Regulates Gut-Renal Axis NCT06031389 | Qianfoshan Hospital | N/A |
| Unknown | Efficacy and Safety of Finerenone in Heart Failure With Reduced Ejection Fraction NCT05974566 | Chongqing Medical University | — |
| Unknown | Application of Hyperspectral Imaging in the Diagnosis of Glomerular Diseases NCT05797051 | Qianfoshan Hospital | — |
| Recruiting | Efficacy and Safety of Telmisartan Compared With Losartan NCT06431477 | Chong Kun Dang Pharmaceutical | Phase 4 |
| Completed | Phase IIb Clinical Trial for the Efficacy and Safety by CU01-1001 for 24 Weeks in Type 2 DM Patients With Albu NCT05718375 | Curacle Co., Ltd. | Phase 2 |
| Completed | Clinical Study to Evaluate the Possible Efficacy and Safety of Levocetirizine in Patients With Diabetic Kidney NCT05638880 | Mostafa Bahaa | Phase 2 |
| Enrolling By Invitation | Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study NCT05530356 | University of Colorado, Denver | — |
| Completed | Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic K NCT05357742 | Medical College of Wisconsin | N/A |
| Recruiting | Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study) NCT05319990 | University of Colorado, Denver | — |
| Unknown | Huangqi Guizhi Wuwu Decoction in CKD Stage 2-4 Diabetic Nephropathy NCT05418465 | The First Affiliated Hospital of Dalian Medical University | N/A |
| Active Not Recruiting | A Pilot Study of Fenofibrate to Prevent Kidney Function Loss in Type 1 Diabetes NCT04929379 | Alessandro Doria | Phase 2 |
| Unknown | The Effects of TMZ on Diabetic Nephropathy NCT05147194 | Tongji Hospital | Phase 2 |
| Completed | Stem Cell Therapy for Chronic Kidney Disease NCT04869761 | LaTonya J. Hickson | Phase 1 |
| Unknown | The Influencing Factors and Mechanism of High Incidence of Thrombotic Events in Patients With MN and DKD NCT05656963 | Yipeng Liu | — |
| Recruiting | Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive Factors NCT04916132 | Herlev Hospital | — |
| Unknown | Prevention In Community Clinics From Diabetic Kidney Disease NCT04988581 | The First Affiliated Hospital of Xiamen University | N/A |
| Completed | First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Dia NCT04880291 | Goldfinch Bio, Inc. | Phase 1 |
| Completed | A Study to Test the Effect of Different Doses of BI 685509 on Kidney Function in People With Diabetic Kidney D NCT04750577 | Boehringer Ingelheim | Phase 2 |
| Unknown | Hyperuricemia and Diabetic Nephropathy NCT04799925 | Assiut University | — |
| Unknown | Possible Role of Roflumilast in Diabetic Nephropathy NCT04755946 | Tanta University | Phase 3 |
| Completed | MRI Biomarkers in Diabetic Kidney Disease NCT04570735 | Poitiers University Hospital | — |
| Completed | Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy NCT04534439 | Aptabio Therapeutics, Inc. | Phase 2 |
| Terminated | A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, NCT04387448 | Goldfinch Bio, Inc. | Phase 2 |
| Completed | Niclosamide Role in Diabetic Nephropathy NCT04317430 | Tanta University | Phase 3 |
| Terminated | Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN) NCT03933956 | Singapore General Hospital | Phase 3 |
| Unknown | Uric Acid Lowering Trial in Youth Onset T2D NCT03899883 | University of Colorado, Denver | Phase 2 |
| Completed | Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance NCT04074668 | University of Colorado, Denver | — |
| Terminated | A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment NCT04235621 | Goldfinch Bio, Inc. | — |
| Completed | Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis NCT03885362 | Imperial College London | N/A |
| Completed | Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients. NCT04380584 | Cairo University | — |
| Unknown | Use of Wharton Jelly in Diabetic Nephropathy NCT03288571 | Sophia Al-Adwan | Phase 1 / Phase 2 |
| Terminated | Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease NCT03840343 | Mayo Clinic | Phase 1 |
| Unknown | Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy NCT04531163 | Al-Azhar University | Phase 2 / Phase 3 |
| Unknown | TCF7L2 Gene Polymorphism and AGEs in Diabetic Nephropathy NCT04084886 | Assiut University | — |
| Active Not Recruiting | MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus NCT03945747 | University of Colorado, Denver | — |
| Unknown | Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians NCT04119167 | Chang Gung Memorial Hospital | — |
| Completed | Evaluation of Coffee Therapy for Improvement of Renal Oxygenation NCT03878277 | University of Colorado, Denver | Phase 2 |
| Unknown | Molecular Analysis of Diabetic Kidney Disease Biopsies NCT04029402 | Unity Health Toronto | — |
| Completed | Magnesium Supplementation in Diabetic Nephropathy NCT03824379 | Ain Shams University | Phase 2 |
| Suspended | Cholesterol Metabolism in Plasma and Interstitial Fluid Among Subjects Undergoing Hemodialysis. NCT03921216 | Karolinska University Hospital | — |
| Unknown | Effects of Fenofibrate Therapy in Diabetic Nephropathy NCT03869931 | Singapore General Hospital | Phase 3 |
| Unknown | Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic Nephropathy NCT03820635 | Assiut University | — |
| Completed | Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function NCT03618420 | University of Colorado, Denver | Phase 1 / Phase 2 |
| Completed | Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes NCT03620773 | University of Colorado, Denver | Phase 1 / Phase 2 |
| Unknown | Efficacy, Safety and Response Predictors of Adjuvant Astragalus Therapy for Diabetic Kidney Disease NCT03535935 | The University of Hong Kong | Phase 2 / Phase 3 |
| Unknown | Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients NCT03573102 | Nahla H Tohami | Phase 4 |
| Completed | Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy. NCT03889236 | Leiden University Medical Center | N/A |
| Suspended | Inflammation and Stem Cells in Diabetic and Chronic Kidney Disease NCT03325322 | Mayo Clinic | Phase 2 |
| Completed | Hypomagnesemia and Diabetic Nephropathy NCT03690180 | Fayoum University | — |
| Completed | This Study Tests a New Medicine Called BI 685509 in Patients That Have Kidney Problems Because of Diabetes. Th NCT03165227 | Boehringer Ingelheim | Phase 1 |
| Completed | This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Diffe NCT03165240 | Boehringer Ingelheim | Phase 1 |
| Completed | PERL Continuous Glucose Monitoring (CGM) Study NCT03334318 | Joslin Diabetes Center | — |
| Unknown | Doppler Ultrasound in Early Detection of Diabetic Nephropathy Type 2 Diabetes Mellitus. NCT03284996 | Assiut University | — |
| Unknown | Serum Immunoglobulin (G) as a Marker of Diabetic Nephropathy NCT03212755 | Assiut University | N/A |
| Unknown | Retrospective Analysis of Renal Prognosis in Patients With Chronic Kidney Disease NCT03201406 | National Taiwan University Hospital | — |
| Unknown | An Intervention to Examine the Effect of Vitamin D on Urine Protein Levels in Type 2 Diabetes NCT03216564 | Hamad Medical Corporation | Phase 3 |
| Completed | Gemigliptin and Biomarkers of Kidney Injury and Vascular Calcification NCT04705506 | Bangkok Metropolitan Administration Medical College and Vajira Hospital | N/A |
| Recruiting | Transformative Research in Diabetic Nephropathy NCT02986984 | University of Pennsylvania | — |
| Active Not Recruiting | The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. NCT01320345 | University of Sydney | Phase 3 |
| Completed | Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy NCT02690883 | Nanfang Hospital, Southern Medical University | Phase 4 |
| Completed | PeRsOnalising Treatment Of Diabetic Nephropathy: NCT03509454 | Peter Rossing | — |
| Unknown | Colchicine for Diabetic Nephropathy Trial NCT02442921 | Sheba Medical Center | Phase 1 / Phase 2 |
| Completed | Renoprotective Effects of Dapagliflozin in Type 2 Diabetes NCT02682563 | M.H.H. Kramer | Phase 4 |
| Completed | A Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects W NCT02552277 | Celularity Incorporated | Phase 2 |
| Unknown | Low Energy Shockwave Therapy (LE-SWT): A Novel Treatment for Chronic Kidney Disease NCT02515461 | Odense University Hospital | N/A |
| Unknown | Semi-individualised Chinese Medicine Treatment as an Adjuvant Management for Diabetic Nephropathy NCT02488252 | The University of Hong Kong | Phase 2 / Phase 3 |
| Completed | Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Ne NCT03006952 | Tehran University of Medical Sciences | Phase 4 |
| Terminated | Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL) NCT02410005 | Weill Cornell Medical College in Qatar | Phase 2 / Phase 3 |
| Completed | Measurement of Endothelial Function and Cardiac Output: New Methods NCT02299960 | Charite University, Berlin, Germany | — |
| Completed | Arterial Stiffness and Complication Risk in Type 2 Diabetes NCT02001532 | Aarhus University Hospital | — |
| Completed | Metabolomic Profiling in Adolescents With Obesity and Diabetes NCT02145572 | University of California, San Diego | — |
| Completed | To Explore the Anti-oxidative Effects and Inflammation Effects of Soy Protein to Renal Function of End Stage D NCT05840796 | Taipei Medical University | N/A |
| Completed | A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes NCT02017171 | Alessandro Doria | Phase 3 |
| Active Not Recruiting | The Hong Kong Diabetes Biobank NCT05282680 | Chinese University of Hong Kong | — |
| Completed | Prevalence of Secondary Hyperparathyroidism Among Patients With Diabetic Nephropathy NCT03137316 | Benha University | — |
| Completed | Safety and Efficacy of Different Oral Doses of BAY94-8862 in Japanese Subjects With Type 2 Diabetes Mellitus a NCT01968668 | Bayer | Phase 2 |
| Unknown | Increased Activity of a Renal Salt Transporter (ENaC) in Diabetic Kidney Disease NCT01918488 | University of Southern Denmark | N/A |
| Completed | Safety and Efficacy of Different Oral Doses of BAY94-8862 in Subjects With Type 2 Diabetes Mellitus and the Cl NCT01874431 | Bayer | Phase 2 |
| Completed | Sympathetic Nervous System Inhibition for the Treatment of Diabetic Kidney Disease NCT01094769 | Baker Heart and Diabetes Institute | Phase 4 |
| Completed | A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 NCT01200394 | Pfizer | Phase 2 |
| Completed | N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy NCT00915200 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Completed | Nitric Oxide (NO) Activity and Diabetic Nephropathy NCT00136188 | University of Erlangen-Nürnberg Medical School | Phase 2 / Phase 3 |
| Withdrawn | Adalat XL vs Diltiazem on Proteinuria and Blood Pressure in Hypertensive Diabetic Patients NCT00713011 | Bayer | Phase 3 |
| Completed | Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant NCT00446251 | University of Washington | Phase 2 |
| Completed | Glucose in Dialysis Water in Diabetics With Chronic Renal Failure NCT00438503 | Regional Hospital Holstebro | Phase 4 |
| Unknown | Comprehensive Management of Diabetic Patients With Renal Impairment : Impact on Blood Pressure and Glycemic Co NCT00306436 | University Hospital, Bordeaux | N/A |
| Completed | Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiti NCT00446459 | University of Washington | Phase 2 |
| Completed | Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy NCT00237952 | Chang Gung Memorial Hospital | N/A |
| Completed | The Effect of Folic Acid Administration in the Progression of Microalbuminuria NCT00737126 | Hospital Universitario Dr. Jose E. Gonzalez | N/A |
| Completed | A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year NCT00168857 | Boehringer Ingelheim | Phase 4 |
| Completed | 1 Year Trial Telmisartan 80 mg Versus Valsartan 160 mg in Hypertensive Type 2 Diabetic Patients With Overt Nep NCT00153023 | Boehringer Ingelheim | Phase 4 |
| Completed | INNOVATION Study - Telmisartan (Micardis) in Incipient Diabetic Nephropathy NCT00153088 | Boehringer Ingelheim | Phase 4 |
| Terminated | Effect of Low Protein Diet in Preventing the Progression of Diabetic Nephropathy NCT00448526 | Kanazawa Medical University | N/A |