NCT02299960

Measurement of Endothelial Function and Cardiac Output: New Methods

Pilot Study: Analysis of Endothelial Function Through Circulating Endothelial Cells and Puls-amplitude-tonometry and of Non-invasive Measurement of Cardiac Output on Exertion in Patients With Heart Failure, Pulmonary Hypertension, Arterial Hypertension and Diabetic Nephropathy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 101 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 35 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is to analyse test-retest-reliability of functional quantification of endothelial dysfunction through puls-amplitude-tonometry in patients with heart failure with preserved/reduced ejection fraction, pulmonary hypertension, arterial hypertension and diabetic nephropathy. In the same group, test-retest-reliability of circulating endothelial cells as well as test-retest reliability of non invasive cardiac output Monitoring will be observed and analysed.

Conditions

• Heart Failure
• Hypertension, Pulmonary
• Hypertension
• Diabetic Nephropathies

Interventions

Type	Name	Description
DEVICE	Endo-PAT	Analysis of endothelial function through pulse-amplitude-tonometry
DEVICE	NICOM	Non-invasive measurement of cardiac output

Timeline

• Start date: 2014-08-01
• Primary completion: 2015-09-01
• Completion: 2015-10-01
• First posted: 2014-11-24
• Last updated: 2016-06-10

Locations

1 site across 1 country: Germany