| Recruiting | A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study) NCT07292246 | Vasileios Kalles | N/A |
| Suspended | Pilot Trial of Preop Partial Radiation in Breast Cancer Patients NCT07178665 | Rutgers, The State University of New Jersey | Phase 1 |
| Not Yet Recruiting | Robotic Nipple Sparing Mastectomy with Immediate Reconstruction NCT06860217 | European Institute of Oncology | N/A |
| Not Yet Recruiting | The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCIS NCT06217458 | Clinical Hospital Center Rijeka | N/A |
| Recruiting | Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-S NCT06902311 | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
| Completed | THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence NCT06388304 | Joanna Arch | N/A |
| Active Not Recruiting | LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive B NCT05900986 | Integro Theranostics | Phase 1 / Phase 2 |
| Recruiting | Delayed Selective Sentinel Node Biopsy for Patients Undergoing Mastectomy for DCIS NCT05912569 | Seoul National University Hospital | N/A |
| Recruiting | Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS) NCT04797299 | Ontario Clinical Oncology Group (OCOG) | — |
| Withdrawn | Partial Chest Wall Radiation Therapy After Surgery for Lymph Node Negative Breast Cancer NCT05436808 | Stony Brook University | EARLY_Phase 1 |
| Recruiting | Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer NCT03936478 | University of Wisconsin, Madison | Phase 2 |
| Active Not Recruiting | The AUS-PREDICT Registry for DCIS Patients With DCISionRT Testing NCT04916808 | PreludeDx | — |
| Unknown | Molecular Analysis of the Sloane Project NCT05868252 | King's College London | — |
| Recruiting | Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ NCT04722692 | Uppsala University | Phase 3 |
| Completed | Pilot Study of a an App to Improve Medication Adherence in Breast Cancer Survivors Receiving AIs NCT04170920 | Indiana University | N/A |
| Completed | Genotype and Phenotype Guided Supplementation of TAMoxifen Standard Therapy With ENDOXifen in Breast Cancer Pa NCT03931928 | Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) | Phase 2 |
| Recruiting | Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer NCT04084730 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Recruiting | Perioperative Mindfulness Proposal NCT04049214 | Hoag Memorial Hospital Presbyterian | N/A |
| Active Not Recruiting | Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast NCT03878342 | UNICANCER | N/A |
| Completed | Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity NCT04245150 | Case Comprehensive Cancer Center | — |
| Terminated | Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery NCT03535506 | Georgetown University | Phase 2 |
| Recruiting | The PREDICT Registry: NCT03448926 | PreludeDx | — |
| Active Not Recruiting | Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS NCT02926911 | Alliance Foundation Trials, LLC. | N/A |
| Active Not Recruiting | Management of Low-risk (Grade I and II) DCIS NCT02492607 | The Netherlands Cancer Institute | N/A |
| Completed | Evaluation of the DCIS Score for Decisions on Radiotherapy in Patients With Low/Intermediate Risk DCIS NCT02766881 | Ontario Clinical Oncology Group (OCOG) | — |
| Completed | Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation NCT02637024 | Ontario Clinical Oncology Group (OCOG) | Phase 2 |
| Terminated | CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI) NCT02365714 | Georgetown University | Phase 1 / Phase 2 |
| Completed | Tumor: Breast Ratio Study NCT02216136 | Washington University School of Medicine | — |
| Completed | Impact of Radiation Therapy on Breast Conservation in DCIS NCT02248662 | Dana-Farber Cancer Institute | — |
| Completed | Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial) NCT01023477 | Inova Health Care Services | Phase 1 / Phase 2 |
| Completed | DC Vaccine for Patients With Ductal Carcinoma In Situ NCT02061332 | Abramson Cancer Center at Penn Medicine | Phase 1 / Phase 2 |
| Completed | Chemoprevention Trial - Anastrozole in Ductal Carcinoma In Situ (DCIS) in Postmenopausal Women NCT00256217 | Rita Sanghvi, Mehta | Phase 2 |
| Completed | MammoSite as Sole Radiation Therapy Technique for Ductal Carcinoma In-Situ NCT00586326 | Hologic, Inc. | Phase 2 |
| Completed | Educational Interventions for Patients With DCIS NCT00148655 | Dana-Farber Cancer Institute | N/A |