Trials / Recruiting
RecruitingNCT04084730
Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
Ultra-Short External Beam-Based Accelerated Partial Breast Irradiation (APBI): A Phase II Toxicity Study Nested With a Non-inferiority Assessment of APBI in New Patient Cohorts
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 280 (estimated)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- Female
- Age
- 45 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine if the dose of radiation therapy that is effective in producing a treatment response, delivered over a shorter treatment period, is a safe approach that causes few or mild side effects in women with newly diagnosed breast cancer or DCIS who have had a lumpectomy procedure.
Conditions
- Invasive Ductal Breast Carcinoma
- Invasive Ductal Carcinoma, Breast
- DCIS
- DCIS Grade 1
- DCIS Grade 2
- Breast Cancer
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Accelerated Partial Breast Irradiation | Treatment will consist of APBI delivered using external beam RT techniques to a dose of 24 Gy in 3 fractions of 8.0 Gy delivered on consecutive weekdays |
Timeline
- Start date
- 2019-08-30
- Primary completion
- 2026-08-30
- Completion
- 2026-08-30
- First posted
- 2019-09-10
- Last updated
- 2025-09-16
Locations
9 sites across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT04084730. Inclusion in this directory is not an endorsement.