| Not Yet Recruiting | Post-market Clinical Follow-up Study of an Isotonic Saline Solution to Manage Nasal Congestion in Case of Flu NCT07257224 | Laboratoires Quinton International S.L. | — |
| Active Not Recruiting | A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Throat Spray on the Incidenc NCT07246850 | Beekeeper's Naturals Inc | N/A |
| Completed | A Clinical Evidence Study Evaluating Quality of Life Parameters Following Treatment With Robitussin NCT06716645 | HALEON | Phase 4 |
| Withdrawn | Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of C NCT05070650 | Sandoz | Phase 3 |
| Completed | Efficacy and Safety of Silfamin for Common Cold NCT06497439 | Dexa Medica Group | Phase 2 |
| Recruiting | Effects of LP28 on Immunity Enhancement in the Elderly NCT06724185 | Synbio Tech Inc. | N/A |
| Recruiting | Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine NCT06531707 | Laboratorios Silanes S.A. de C.V. | Phase 3 |
| Completed | Effectiveness of a Nasal Spray on Viral Respiratory Infections NCT06278324 | CEN Biotech | N/A |
| Unknown | Efficacy and Safety of Ingavirin®, Capsules, 60 mg, in Children With Influenza and Other Acute Respiratory Vir NCT06315400 | Valenta Pharm JSC | Phase 4 |
| Recruiting | A Study of the Efficacy and Safety of Antiwei Granules in the Treatment of Common Cold NCT06697886 | Tasly Pharmaceutical Group Co., Ltd | Phase 3 |
| Unknown | Commercially Available Cannabis Products for Immune Support NCT05944705 | Center For Interventional Pain and Spine | — |
| Completed | Supporting Parents to Choose Wisely NCT06005337 | University of Alberta | N/A |
| Completed | Post Market Clinical Follow-Up Study - Medical Device KalobaNaso NCT05960318 | Schwabe Pharma Italia | — |
| Completed | BАbykids Spray In Common Cold NCT05819203 | Lallemand Pharma AG | N/A |
| Completed | Testing the Efficacy in Adults With Cold of HEalsea Rescue* NCT05819190 | Lallemand Pharma AG | N/A |
| Completed | Otrivine: Quality of Life (QoL) Impact in a Real-World Setting NCT05556148 | HALEON | Phase 4 |
| Completed | Alleviation of Common Cold Symptoms NCT06106880 | Applied Biological Laboratories Inc | Phase 1 |
| Completed | Efficacy and Safety of XC8, Film-coated Tablets, 40 mg in Patients With Dry Non-productive Cough Against Acute NCT05273619 | Valenta Pharm JSC | Phase 3 |
| Completed | The Preventive Effectiveness of the Individualized Jade Wind-Barrier Herbal Tea Bag on the Common Cold in Elde NCT05640570 | Hong Kong Baptist University | Phase 2 |
| Completed | Symbiofilm Trial in Allergic Kids (SYMBIOFILM-TAK) NCT05034328 | Lallemand Pharma AG | — |
| Completed | A Study of Olynth Saline/Ectomed Nasal Drops/Spray Based Upon Previous Usage NCT05126407 | Johnson & Johnson Consumer Inc. (J&JCI) | — |
| Terminated | Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects NCT05244148 | Church & Dwight Company, Inc. | N/A |
| Completed | Efficacy and Safety of Ingavirin®, Syrup, 30 mg/5 ml, in Children With Influenza and Other Acute Respiratory V NCT05269290 | Valenta Pharm JSC | Phase 3 |
| Completed | Study to Evaluate the Efficacy of EZC Pak in Adults With Upper Respiratory Infection (URI) NCT04943575 | PPC Pharmaceuticals | N/A |
| Completed | Efficacy and Safety of XC8, Film-coated Tablets, 10 mg in Patients With Dry Non-productive Cough Against Acute NCT05269329 | Valenta Pharm JSC | Phase 2 |
| Unknown | The Effect of Probiotic and Zinc Supplementation on the Common Cold NCT04672850 | Lund University | N/A |
| Completed | Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care NCT04681001 | Marinomed Biotech AG | N/A |
| Completed | Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus In NCT05002179 | A. Vogel AG | Phase 4 |
| Completed | Study to Investigate if Sucking a Coldamaris Lozenge Elutes Sufficient Iota-carrageenan to Inactivate Usual Co NCT04533906 | Marinomed Biotech AG | N/A |
| Completed | Audio Data Collection for Identification and Classification of Coughing NCT04326309 | HealthMode Inc. | — |
| Withdrawn | Clinical Trial to Optimise Levels of Vitamin D for Rhinovirus Protection NCT04368520 | Queen Mary University of London | Phase 2 |
| Unknown | Herbal Medicine 'Eungyosan' and 'Samsoeum' for Common Cold NCT04073511 | Korean Medicine Hospital of Pusan National University | N/A |
| Completed | Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda NCT04144491 | VU University of Amsterdam | N/A |
| Withdrawn | Efficacy and Safety of Irlanda-1-Association on the Treatment of Common Cold in Children NCT02656888 | EMS | Phase 3 |
| Withdrawn | Efficacy and Safety of Irlanda-2 Association on the Treatment of Common Cold NCT02656914 | EMS | Phase 3 |
| Completed | Duration of ColdZyme® II NCT03901846 | Enzymatica AB | N/A |
| Completed | Double-blind, Randomized, Parallel-group, Placebo-controlled Study to Evaluate Efficacy of CMS008618 for Commo NCT03794804 | Enzymatica AB | N/A |
| Completed | Digital Online Consultations - Effects on Antibiotic Prescribing and Health Care Utilization in Primary Care NCT03474887 | Region Skane | — |
| Completed | To Investigate the Gastrointestinal Behaviour of Two Triple Combination Products in Healthy Male Volunteers NCT03415243 | GlaxoSmithKline | Phase 1 |
| Completed | Evaluation of the Use of Various Assessments of Common Cold Symptoms for Proof of Efficacy of ColdZyme Mouth S NCT03831763 | Enzymatica AB | N/A |
| Completed | The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold NCT03309995 | University of Helsinki | N/A |
| Terminated | Randomized, Double-blind, Placebo-Controlled, Efficacy Study of a New Formulation of Phenylephrine HCL in the NCT03339726 | Johnson & Johnson Consumer Inc. (J&JCI) | Phase 2 |
| Completed | PEACe: Ivy, Thyme and Cisti Extract (Phytus) Efficacy in Acute Cough NCT02981147 | PharmEvo Pvt Ltd | Phase 4 |
| Withdrawn | Echinaforce Junior Bioavailability Trial NCT03070314 | A. Vogel AG | Phase 4 |
| Completed | To Evaluate the Efficacy and Safety of 1146A Nasal Spray in Adult Participants With Symptoms of Common Cold NCT03005067 | GlaxoSmithKline | Phase 2 |
| Completed | Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department NCT02957136 | University of California, Davis | N/A |
| Completed | Local Nasal Tolerability and Safety Study of 1146A in Healthy Adult Participants NCT02832362 | GlaxoSmithKline | Phase 1 |
| Withdrawn | Evaluation of the Efficacy and Safety of Two Ibuprofen Combination Products for the Treatment of the Common Co NCT01938144 | Pfizer | Phase 3 |
| Completed | Evaluation of ColdZyme® on Experimentally Induced Common Cold. NCT02479750 | Enzymatica AB | N/A |
| Completed | Effect of Probiotic on Rhinovirus Induced Colds NCT02679807 | University of Virginia | N/A |
| Completed | Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough NCT02822287 | GlaxoSmithKline | Phase 3 |
| Completed | Efficacy and Safety Study of Ingavirin® to Treat Influenza and Other Acute Respiratory Viral Infections in Pat NCT02644018 | Valenta Pharm JSC | Phase 3 |
| Completed | Efficacy and Safety of Resveratrol and Carbossimetyl Beta Glucan in Treatment of Upper Airways Disease in Infa NCT03683108 | Policlinico Hospital | Phase 3 |
| Completed | Nasal Swab Study to Explore the Nasal Microbia NCT02535442 | Kimberly-Clark Corporation | — |
| Completed | Effect of OC459 on the Response to Rhinovirus Challenge in Asthma NCT02660489 | Imperial College London | Phase 2 |
| Completed | The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine M NCT02246166 | GlaxoSmithKline | Phase 4 |
| Completed | DBRCT on the Effect of Wheat Polysaccharides on Common Cold Infections in Elderly NCT02451163 | Clinical Research Center Kiel GmbH | Phase 2 |
| Completed | Efficacy and Safety Study of Ingavirin® to Treat Influenza and Acute Respiratory Viral Infections in Children NCT03191097 | Valenta Pharm JSC | Phase 3 |
| Completed | Hypertonic Saline Nasal Irrigation and Gargling for the Common Cold. NCT02438579 | NHS Lothian | N/A |
| Completed | Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides) NCT02174653 | Dr. Willmar Schwabe GmbH & Co. KG | Phase 3 |
| Terminated | Benefit and Tolerability of IQP-AS-105 in Reducing Susceptibility to Upper Respiratory Tract Infections NCT01964885 | InQpharm Group | Phase 3 |
| Completed | Iota-Carrageenan Nasal Spray in Common Cold NCT01944631 | Boehringer Ingelheim | Phase 4 |
| Completed | Evaluation of ColdZyme® Mouth Spray on Prevention and Alleviation of Rhinovirus Induced Common Cold NCT02522949 | Enzymatica AB | N/A |
| Completed | A Study of Nasal Glucagon in Participants With a Common Cold NCT02778100 | Eli Lilly and Company | Phase 1 |
| Completed | Experimental Human Rhinovirus Infection NCT01823640 | Radboud University Medical Center | Phase 1 |
| Completed | Glucose Oxidase as Treatment Against Common Cold NCT01883440 | Krister Tano | Phase 2 |
| Completed | A Nasal Spray With Glucose Oxidase as a Treatment of Common Cold NCT01883453 | Umeå University | Phase 2 |
| Completed | Efficacy and Safety Study of Homeopathic Oral Antibodies to Treat Viral Upper Respiratory Tract Infections NCT01651715 | Theranor s.p.r.l | Phase 1 / Phase 2 |
| Completed | Effect of Probiotic on the Innate and Adaptive Host Response to Rhinovirus (EPIARR) NCT01669603 | University of Virginia | N/A |
| Completed | A Study of an Experimental Nasal Spray in Subjects With Early Signs of the Common Cold NCT01488604 | McNeil AB | N/A |
| Completed | Efficacy and Safety Study of Ingavirin® to Treat Influenza and Acute Respiratory Viral Infections in Patients NCT03206346 | Valenta Pharm JSC | Phase 3 |
| Completed | A Double-blind, Randomised, Parallel Group,Comparative Study With Rose-hip Liquid and Placebo Given to Healthy NCT01459952 | Hyben Vital ApS | Phase 3 |
| Completed | Effects of Two Doses of a Common Cold Treatment on Alertness NCT01686646 | GlaxoSmithKline | Phase 3 |
| Completed | Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System NCT01677715 | Inner Mongolia Yili Industrial Group Co., Ltd | N/A |
| Completed | A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies NCT01332578 | GlaxoSmithKline | Phase 4 |
| Completed | Study of Yili Lactoferrin ShuHua Milk in the Improvement of Human Immunization NCT01677702 | Inner Mongolia Yili Industrial Group Co., Ltd | N/A |
| Completed | Effects of a Common Cold Treatment on Cognitive Function NCT01466348 | GlaxoSmithKline | Phase 4 |
| Terminated | Acute Cough Study In Children NCT01257542 | Pfizer | Phase 4 |
| Completed | Study of Post-Exposure Ingavirin® Prophylaxis of Influenza and Acute Respiratory Viral Infections NCT03189537 | Valenta Pharm JSC | Phase 3 |
| Completed | Effect of Paracetamol on the Common Cold NCT01277081 | GlaxoSmithKline | Phase 2 |
| Completed | Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu NCT01158326 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Completed | Safety and Efficacy Study of Oral XIGO Tablets to Treat The Common Cold NCT01092039 | Xigo Health LLC | N/A |
| Completed | Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections i NCT03154515 | Valenta Pharm JSC | Phase 4 |
| Completed | Mucinex Exploratory Cold Study NCT01046136 | Reckitt Benckiser Inc. | Phase 2 |
| Completed | Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections NCT01728090 | Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental | Phase 4 |
| Completed | Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold NCT00963443 | Bayer | Phase 3 |
| Unknown | Efficacy Study of A Lotion to Prevent Common Colds NCT00993759 | The Dial Corporation | Phase 2 |
| Unknown | Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu NCT00940836 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Completed | Encapsulated Juice Powder Concentrate for Preventing Common Cold Symptoms NCT00778648 | Charite University, Berlin, Germany | N/A |
| Completed | Efficacy Trial of 3804-250A in the Prevention of Cold Illnesses NCT00762476 | The Dial Corporation | Phase 2 |
| Completed | Trial to Evaluate the Use of Pomegranate Concentrate (POMx) for the Prevention of Experimental Rhinovirus Infe NCT00655031 | POM Wonderful LLC | Phase 2 |
| Completed | Effectiveness of Local Application of Warm Air in Patients With Common Cold (HELI Study) NCT00552981 | Charite University, Berlin, Germany | N/A |
| Completed | Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects NCT00452270 | Novartis | Phase 3 |
| Completed | Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold NCT00378144 | McNeil AB | Phase 4 |
| Completed | Pomegranate Products for Prevention of Common Cold NCT00617318 | Texas Heart Institute | Phase 3 |
| Completed | Evaluation of Safety of ZyComb® In Patients With Common Cold - ZIP 3000 (XY-005-IM) NCT00480194 | Nycomed | — |
| Completed | Stopping Upper Respiratory Infections and Flu in the Family: The Stuffy Trial NCT00448981 | Centers for Disease Control and Prevention | N/A |
| Completed | The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years NCT00405509 | West Penn Allegheny Health System | — |
| Completed | Effects of Pleconaril Nasal Spray on Common Cold Symptoms and Asthma Exacerbations Following Rhinovirus Exposu NCT00394914 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Kinetics of Etheric Oils, Smart Textiles vs. Ointment NCT00299559 | Technische Universität Dresden | Phase 1 |
| Completed | Echinacea, Propolis and Vitamin C for URI Prevention in Preschoolers NCT00231218 | The Cleveland Clinic | Phase 3 |
| Completed | Placebo and Active Controlled Study to Assess Efficacy and Tolerability of Aspirin Plus Pseudoephedrine NCT01062360 | Bayer | Phase 3 |
| Completed | Symptomatic Treatment of Common Cold Symptoms NCT01033526 | Bayer | Phase 4 |
| Completed | Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Sym NCT01361399 | Bayer | Phase 3 |
| Completed | Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Th NCT01465009 | Bayer | Phase 4 |
| Completed | Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) NCT00065715 | University of Wisconsin, Madison | Phase 3 |
| Completed | Evaluation of Echinacea for the Common Cold NCT00032500 | National Center for Complementary and Integrative Health (NCCIH) | Phase 2 |
| Completed | Efficacy of Homeopathic Nasal Formulation for Management of Experimental Rhinoviral Colds NCT00358774 | University of Wisconsin, Madison | Phase 1 / Phase 2 |
| Completed | A Trial of Echinacea in Children NCT00029211 | National Center for Complementary and Integrative Health (NCCIH) | Phase 3 |
| Withdrawn | Study Comparing 3 Formulations to Evaluate the Efficacy and Safety of the Inflammatory Symptoms of the Upper R NCT00967759 | Ache Laboratorios Farmaceuticos S.A. | Phase 3 |