Trials / Completed
CompletedNCT01332578
A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 25 (actual)
- Sponsor
- GlaxoSmithKline · Industry
- Sex
- Male
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The study is designed to investigate whether paracetamol from a hot remedy reaches the plasma faster than standard paracetamol tablets. The study will also assess the gastrointestinal transit of two oral cold and influenza ('flu') formulations using gamma scintigraphy. It is postulated that paracetamol in solution, such as from cold and 'flu' hot remedies, provides a greater early exposure compared to standard paracetamol tablets. In addition, the pharmacokinetic (PK) profile of paracetamol in the two formulations will be investigated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Paracetamol | Present in both test and active comparator |
| DRUG | Phenylephrine | Test product |
| DRUG | Ascorbic Acid | Test product |
Timeline
- Start date
- 2011-05-01
- Primary completion
- 2011-06-01
- Completion
- 2011-06-01
- First posted
- 2011-04-11
- Last updated
- 2015-06-01
- Results posted
- 2015-06-01
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT01332578. Inclusion in this directory is not an endorsement.