Clinical Trials Directory

Trials / Terminated

TerminatedNCT01257542

Acute Cough Study In Children

A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled, Single-Dose, Pilot Study To Evaluate Efficacy Of Dextromethorphan Hydrobromide On Acute Cough In A Pediatric Population

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
140 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
6 Years – 11 Years
Healthy volunteers
Not accepted

Summary

15 mg dextromethorphan hydrobromide will be better than placebo with respect to reducing the number of coughs over 6 hours and reducing the subjective severity of cough over 6 hours.

Detailed description

In light of protocol changes required due to methodological and operational issues, including background noise in cough recordings which could impact data interpretation, the study has been terminated.

Conditions

Interventions

TypeNameDescription
DRUGDextromethorphanA single 10 mL dose of Children's Triaminic Syrup (Dextromethorphan Hydrobromide 7.5 mg per 5 mL (total dose of 15 mg)
DRUGPlaceboA single 10 mL dose of matching placebo syrup

Timeline

Start date
2010-12-01
Primary completion
2011-03-01
Completion
2011-03-01
First posted
2010-12-09
Last updated
2012-09-20
Results posted
2012-09-20

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01257542. Inclusion in this directory is not an endorsement.