| Suspended | Stanford Spine Keeper - Managing Your Low Back Pain NCT05443503 | Stanford University | N/A |
| Not Yet Recruiting | Durability of Yoga for Veterans With Low Back Pain NCT07053787 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT NCT07158567 | VA Office of Research and Development | Phase 3 |
| Not Yet Recruiting | Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive NCT05935761 | VA Office of Research and Development | Phase 2 |
| Not Yet Recruiting | Treatment of Chronic Lower Back Pain With a Combination of Electrical Stimulation, LED, and Laser Therapy NCT07313826 | Defense and Veterans Center for Integrative Pain Management | N/A |
| Not Yet Recruiting | Impact of Leisure Activities on Quality of Life in Low Back Pain NCT07467499 | Centre Hospitalier Valida | — |
| Recruiting | Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome NCT07463729 | University of Rzeszow | N/A |
| Not Yet Recruiting | Virtual Reality-Based Rehabilitation Versus Conventional Therapy in Patients With Chronic Low Back Pain NCT07463105 | University of Rzeszow | N/A |
| Not Yet Recruiting | Validation of a Virtual Reality Timed Up and Go Test in Adults With Chronic Non-Specific Low Back Pain NCT07402499 | Selcuk University | — |
| Not Yet Recruiting | Effect of Passive Versus Active Aquatic Therapy Compared With Conventional Physiotherapy for Chronic Low Back NCT07196826 | Gulf Medical University | N/A |
| Not Yet Recruiting | Effect of Connective Tissue Massage in Low Back Pain NCT07462832 | Okan University | N/A |
| Not Yet Recruiting | Effectiveness of Thread-Embedding Acupuncture at EX-B2 on the Oswestry Disability Index and Finger-to-Floor Di NCT07395102 | Indonesia University | N/A |
| Recruiting | MBM and taVNS for Low Back Pain and Depressive Symptoms NCT07415941 | Florida State University | N/A |
| Not Yet Recruiting | Pilates and Resistance Training for Pain, Disability, and Sleep in Chronic Low Back Pain NCT07291934 | Al-Azhar University | N/A |
| Not Yet Recruiting | Pain Neuroscience Education Combined With Lumbar Stabilization Exercises on Disability and Kinesiophobia Among NCT07307859 | Al-Azhar University | N/A |
| Recruiting | Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression NCT06419439 | VA Office of Research and Development | Phase 2 |
| Recruiting | Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control NCT07190807 | Boston Scientific Corporation | N/A |
| Enrolling By Invitation | Efficacy of Low-Dose Laser Acupuncture for Low Back Pain NCT07461363 | Mun Fei Yam | N/A |
| Recruiting | Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection in Chronic Low NCT07241559 | Ankara City Hospital Bilkent | N/A |
| Recruiting | The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chron NCT07132762 | Pamukkale University | N/A |
| Withdrawn | Stem Cells vs. Steroids for Discogenic Back Pain NCT04735185 | Johns Hopkins University | N/A |
| Recruiting | Meditation for Older Adults With Chronic Low Back Pain NCT06384001 | Florida State University | N/A |
| Not Yet Recruiting | Physical Activity and Exercise for Disability and Improving Mental Health in Elderly With Chronic Low Back Pai NCT07178561 | Al-Azhar University | N/A |
| Recruiting | Movement Performance in Persons With Chronic Back Pain NCT06891625 | Karolinska Institutet | N/A |
| Recruiting | Modulation Effect of tACS on Chronic Low Back Pain NCT06568198 | Massachusetts General Hospital | Phase 2 |
| Completed | Pain Neuroscience Education Delivered During Aerobic Exercise Versus Exercise Alone NCT07152171 | University of Chile | N/A |
| Recruiting | Active Music-Based Intervention in Patients With Chronic Low Back Pain NCT06940063 | Sharon Wang-Price | N/A |
| Recruiting | Expressive Art Therapy for Elder Adults With Chronic Low Back Pain NCT07141082 | The Hong Kong Polytechnic University | N/A |
| Recruiting | AuriculoTherapy NeuroImaging NCT06825390 | Keith M Vogt | N/A |
| Not Yet Recruiting | Effect of Kinetic Control in Lumbosacral Radiculopathy. NCT07079202 | Madonna Maher Ezzat Yassa | N/A |
| Recruiting | The 6 Minute Step Test in Chronic Low Back Pain NCT07028034 | Kirsehir Ahi Evran Universitesi | — |
| Recruiting | Clinician Satisfaction With the VERABAND™ NCT06080464 | University of Michigan | N/A |
| Enrolling By Invitation | Chronic Pain Treatment Whith Auricular Laserpuncture NCT07010627 | Universidade do Vale do Paraíba | — |
| Enrolling By Invitation | Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain NCT06804551 | University of Kansas Medical Center | N/A |
| Recruiting | Weight Reduction in CLBP NCT04824248 | Vrije Universiteit Brussel | N/A |
| Recruiting | Telerehabilitation for Patients With Chronic Low Back Pain (TeleBACK Clinical Trial) NCT06821607 | Johns Hopkins University | N/A |
| Recruiting | Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain NCT06827262 | Boston Scientific Corporation | — |
| Recruiting | VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study NCT06724679 | University Hospital, Angers | N/A |
| Active Not Recruiting | Effects Of Inversion Table Therapy Vs MT On Pain And Lumbar Flexibility In Patients With Chronic Low Back Pain NCT07055802 | Superior University | N/A |
| Completed | McKenzie vs Pilates Exercises in People With Chronic Low Back Pain NCT06875921 | International Hellenic University | N/A |
| Not Yet Recruiting | Effects of Dynamic Neuromuscular Stabilization on Pain, Posture, and Respiratory Strength in Chronic Low Back NCT06807710 | Uskudar University | N/A |
| Recruiting | HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain NCT06931158 | Rhode Island Hospital | N/A |
| Recruiting | Evaluation of the Benefit and Safety of Localized Tissue Hydration in the Management of Chronic Low Back Pain NCT06471998 | GCS Ramsay Santé pour l'Enseignement et la Recherche | Phase 2 |
| Recruiting | Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity NCT06831994 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Enrolling By Invitation | Mapping Stress and Pain Interactions (G072323N) NCT06892977 | University Ghent | — |
| Completed | Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain NCT06810245 | Contineum Therapeutics | Phase 1 |
| Recruiting | The Relationship Between Upper Extremity Exercise Capacity, Respiratory and Peripheral Muscle Strength in Chro NCT06806514 | Kirsehir Ahi Evran Universitesi | — |
| Not Yet Recruiting | Comparative Effects of Motor Control and Isolated Strengthening Lumbar Exercises on Functional Outcomes in Pat NCT06778694 | University of Faisalabad | N/A |
| Recruiting | Improving Health for Patients With Chronic LBP in Rural Communities Through Telerehabilitation NCT06471920 | Johns Hopkins University | N/A |
| Recruiting | Instrument Assisted Soft Tissue Mobilization Versus Myofascial Release in Patients With Chronic Non¬Specific L NCT06796881 | Cairo University | N/A |
| Recruiting | Foot Reflexology for Chronic Low Back Pain NCT06828016 | Fu Jen Catholic University Hospital | N/A |
| Recruiting | Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain NCT06679205 | University of Barcelona | N/A |
| Not Yet Recruiting | Home-Based Rehabilitation Training for Chronic Low Back Pain Patients NCT05998434 | First Affiliated Hospital, Sun Yat-Sen University | N/A |
| Enrolling By Invitation | The Effects of High-definition Transcranial Direct Current Stimulation on Balance Control in Older Adults With NCT06706479 | The Hong Kong Polytechnic University | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of HCP1004 in Chronic Low-Back Pain Patients NCT06595004 | Hanmi Pharmaceutical Company Limited | Phase 3 |
| Completed | The Glittre Activities of Daily Living Test in Chronic Low Back Pain NCT06675370 | Kirsehir Ahi Evran Universitesi | — |
| Completed | Comparing the Effects of Ischemic Compression and Kinesiology Taping Techniques NCT07425301 | Hasan Kalyoncu University | N/A |
| Completed | Integrative Breathwork Intervention for Chronic Pain NCT06546956 | University of Florida | Phase 1 / Phase 2 |
| Recruiting | Assessing Central Aspects of Pain NCT06518278 | University of Nottingham | — |
| Recruiting | The Ability of Chronic Pain Patients to Self-diagnose Their Chief Source of Low Back Pain NCT06630676 | Northwestern University | N/A |
| Enrolling By Invitation | RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain NCT07338877 | EPC Education s.r.o. | — |
| Completed | Cupping Therapy in Chronic Nonspecific Low Back Pain NCT06193603 | Iran University of Medical Sciences | N/A |
| Recruiting | Motivations, Obstacles and Opportunities for Using a Health Application to Encourage Physical Activity in Peop NCT06517342 | University Hospital, Clermont-Ferrand | — |
| Completed | Research Study on Patient Education for People With Chronic Low Back Pain NCT06492642 | University of Pittsburgh | N/A |
| Not Yet Recruiting | The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain NCT06347328 | Centre Hospitalier Universitaire de Nice | N/A |
| Not Yet Recruiting | Dry Needling Versus Percutaneous Electrolysis in Lumbar Multifidus Muscles in Patients With Chronic Low Back P NCT06505161 | University of Alcala | N/A |
| Not Yet Recruiting | Personalized and Automated Digital Coaching in People With Non-specific Chronic Low Back Pain NCT06498271 | Assistance Publique - Hôpitaux de Paris | N/A |
| Not Yet Recruiting | Lateralization Performance in Chronic Low Back Pain NCT06544850 | Inonu University | — |
| Recruiting | Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment NCT06106191 | Boston Medical Center | N/A |
| Completed | Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain NCT06814470 | Massachusetts General Hospital | N/A |
| Recruiting | Comparative Effects of Dry Needling Versus Soft Tissue Mobilization on Hamstring Tightness NCT06751160 | Riphah International University | N/A |
| Terminated | Alberta Rehabilitation Advice Line SelfBack Study NCT06484751 | University of Alberta | N/A |
| Recruiting | Feasibility, Effectiveness, and Patient Experience of Online Acceptance and Commitment Therapy Plus Exercises NCT06576414 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Contribution of the Podiatrist-Posturologist in the Evaluation of the Link Between the Stabilometric Parameter NCT05540548 | University Hospital, Lille | — |
| Completed | "Psychological Intervention Enhanced by Virtual Reality for the Improvement of Appreciation of Body Functional NCT06506604 | University of Valencia | N/A |
| Recruiting | Technology Supported High Intensity Training in Chronic Low Back Pain: the Techno-HIT Trial NCT06491121 | Hasselt University | N/A |
| Recruiting | Alberta Chiropractic SelfBack Study NCT06347991 | University of Alberta | N/A |
| Recruiting | Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chroni NCT06053242 | Creative Medical Technology Holdings Inc | Phase 1 / Phase 2 |
| Completed | Investigation of the Effect of Different Intensity Stabilization Exercises on Core Muscles NCT06227767 | Hasan Kalyoncu University | N/A |
| Recruiting | Psilocybin in Chronic Low Back Pain and Depression NCT06355414 | Johns Hopkins University | Phase 1 |
| Completed | Effects of Pain Neuroscience Education and Virtual Reality in Patients With Chronic Low Back Pain NCT06410027 | Universidad de Granada | N/A |
| Recruiting | The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial NCT06169488 | Oslo University Hospital | N/A |
| Completed | Efficacy and Safety in the Combination of Celecoxib / Pregabalin / Vitamin B for Low Back Chronic Pain NCT06516094 | Laboratorios Silanes S.A. de C.V. | Phase 3 |
| Not Yet Recruiting | Effect of Chronic Low Back Pain Treatment on Temporomandibular Disorder" NCT06343155 | Medipol University | N/A |
| Recruiting | Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain NCT06310226 | University of California, Los Angeles | N/A |
| Unknown | Effectiveness of Pain Neuroscience Education on Clinical and Psychosocial Variables in Chronic Low Back Pain NCT05953454 | Universidad Santo Tomas, Chile | N/A |
| Completed | Lumbar Support Belt for Low-Back Pain in Office Workers NCT07030816 | General Incorporated Foundation Ryukyuseimeisaiseikai, Ryusei Hospital. | N/A |
| Withdrawn | Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device NCT05944081 | Aesculap AG | — |
| Recruiting | Answerability and Minimal Clinical Significance of the Pain Questionnaires NCT06271447 | Acibadem University | — |
| Recruiting | The Surface EMG Biofeedback as an Alternative Therapy to Reduce Chronic Low Back Pain NCT06306833 | Amaila Fazal [afazal] | N/A |
| Recruiting | Psychometric Properties of Pain Scale in Low Back Pain NCT06113185 | Acibadem University | — |
| Completed | Effects of a CSE With ADIM in Chronic Non-specific Low Back Pain With Lumbar Instability Using Telerehabilitat NCT06321393 | Khon Kaen University | N/A |
| Completed | Digital Clinical Hypnosis for Chronic Pain Management NCT06050083 | University of Washington | N/A |
| Unknown | Discure Technologies Feasibility Study for DDD NCT06127745 | Discure Technologies Ltd. | N/A |
| Unknown | Combining Physiotherapy Group Exercise With Acceptance and Commitment Therapy in Elderly With Chronic Low Back NCT06148896 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Detection of EEG-Based Biomarkers of Chronic Low Back Pain NCT06025201 | Stanford University | N/A |
| Completed | Efficacy of Mobilization With Movement on Conditioned Pain Modulation in Chronic Low Back Pain Patients NCT06078033 | Eleuterio Atanasio Sánchez Romero | N/A |
| Recruiting | Psilocybin Therapy for Chronic Low Back Pain NCT05351541 | Joshua Woolley, MD, PhD | Phase 1 / Phase 2 |
| Unknown | What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physi NCT06094517 | Sheffield Hallam University | — |
| Unknown | Transcranial Direct Current Stimulation (tDCS) Combined With Aerobic Exercise in Chronic Nonspecific Low Back NCT05830851 | European University of Madrid | N/A |
| Recruiting | Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain NCT05812885 | University of Hartford | N/A |
| Unknown | Comparison of Positional Release and Manual Pressure Technique in Chronic Low Back Pain NCT06240949 | Riphah International University | N/A |
| Recruiting | The METRIC Study Protocol NCT05986370 | Université du Québec à Trois-Rivières | N/A |
| Terminated | Clinical Investigation to Assess the Clinical Performance of the LumbaCure® Intervention on Chronic Low Back P NCT06138002 | Odix | N/A |
| Recruiting | Mobile Neurofeedback for Low Back Pain NCT05669027 | Duke University | N/A |
| Completed | Ultrasound Imaging for Myofascial Pain NCT05928884 | University of Pittsburgh | — |
| Unknown | The Impact of Positive, Neutral and Negative Expectation Speech on Manipulative Therapy Effects NCT05996991 | Universidade Federal de Sao Carlos | N/A |
| Recruiting | Motivational Support Program in Chronic Low Back Pain After Multidisciplinary Functional Rehabilitation NCT05780021 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Using Non-Weightbearing Stationary Elliptical Machines for Patients with Chronic Low Back Pain NCT05724160 | Massachusetts General Hospital | N/A |
| Unknown | Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults NCT06030128 | The Hong Kong Polytechnic University | N/A |
| Completed | Mobile App-delivered Sleep Therapy (SleepFix) for Individuals With Chronic Low Back Pain and Insomnia NCT05846087 | Woolcock Institute of Medical Research | N/A |
| Recruiting | Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain NCT05963451 | Université de Sherbrooke | — |
| Recruiting | Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low NCT06818175 | Edward Via Virginia College of Osteopathic Medicine | N/A |
| Suspended | Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity NCT05956067 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP) NCT05757609 | Stephane ARMAND | N/A |
| Completed | Effects of Posterior-anterior Vertebral Mobilization Followed by Prone Press-up Exercise in Nonspecific Low Ba NCT05997069 | Dr. Aftab Ahmed Mirza Baig | N/A |
| Completed | Multidisciplinary Digital Therapeutics of Chronic Lower Back Pain Versus Usual Care NCT05940025 | EverEx Inc. | N/A |
| Unknown | Sensory Nerve Function and Exercise Therapy Response in Chronic Low Back Pain NCT05972369 | Ahram Canadian University | — |
| Unknown | The Feasibility, Potential Efficacy, and Experiences of Using a Group-based Acceptance and Commitment Therapy NCT05919446 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Implementation of the Specific Treatment of Problems of the Spine Approach in Bangladesh NCT05880212 | Mohammad Ali | N/A |
| Completed | Effectiveness of Electrotherapy Treatment in Chronic Low Back Pain NCT06638229 | Hacettepe University | N/A |
| Unknown | Conditioned Pain Modulation in Localized vs Widespread Chronic Low Back Pain NCT05972395 | Ahram Canadian University | — |
| Recruiting | YOga for Patients with Chronic BACK Pain and Poor PROgnosis NCT05953155 | Federal University of Minas Gerais | N/A |
| Unknown | Low Back Pain and Motor Control in Soccer Players NCT05934201 | Hacettepe University | — |
| Recruiting | Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA NCT05754190 | Brown University | — |
| Unknown | Effect of Plantar Fascia Release on Patients With Chronic Non-specific Low Back Pain NCT05892783 | Cairo University | N/A |
| Completed | Validation of the Evaluation of the Perception of Physical Activity Questionnaire Adapted to Chronic Low Back NCT05942196 | University Hospital, Clermont-Ferrand | — |
| Unknown | Feasibility of an Interprofessional Rehabilitation Program for Chronic Low Back Patients in the Ethiopian Heal NCT05866146 | Queen's University | N/A |
| Unknown | Virtual Reality Based Physical Therapy for Patients With Lower Back Pain NCT05859321 | University of Lahore | N/A |
| Active Not Recruiting | Ultra Low Frequency Spinal Cord Stimulation for Chronic Low Back Pain NCT05837234 | Presidio Medical, Inc | N/A |
| Unknown | Bronkow Program and Lumbar Stabilization Exercises in Chronic Non Specific Low Back Pain NCT06110026 | Riphah International University | N/A |
| Terminated | Manual Therapy/Exercises vs. Physiotherapy/Back School vs. Waiting List in Patients With Chronic Low Back Pain NCT05843149 | Charite University, Berlin, Germany | N/A |
| Completed | Effect of Core Muscles Training On Patients With Chronic Mechanical Low Back Pain According To SALIBA'S Postur NCT06296667 | Cairo University | N/A |
| Unknown | Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method NCT05930236 | Erasme University Hospital | N/A |
| Recruiting | Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-cente NCT05811624 | Vrije Universiteit Brussel | N/A |
| Unknown | Exercise, PNE and Cognitive Training in Individuals With Chronic Low Back Pain NCT05777343 | Aveiro University | N/A |
| Completed | The Effects of Sacroiliac Joint Dysfunction on Gait and Disability NCT05786118 | Kutahya Health Sciences University | — |
| Completed | The Effect of an Acute Bout of Exercise on Pain Sensitivity and Clinical Pain in Adults With Chronic Low Back NCT05779748 | Taif University | N/A |
| Unknown | Comparative Effects of Mulligan Straight Leg Raise Technique Versus Slump Stretching on Pain, Disability and H NCT05779891 | Sahreen Anwar | N/A |
| Unknown | Evaluation of Therapeutic Management in Chronic Low Back Pain Patients NCT05209854 | Poitiers University Hospital | — |
| Unknown | Locomotion Strategies of Low Back Pain Patients in a Dynamic Environment NCT05851118 | University of Rennes 2 | — |
| Unknown | Virtual Reality Integrated Within Physiotherapy for Patients With Complex Chronic Low Back Pain NCT05701891 | HAN University of Applied Sciences | N/A |
| Completed | Telehealth Mindfulness After Spine Surgery NCT05698914 | Vanderbilt University Medical Center | N/A |
| Completed | Effects of Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain NCT05848076 | Riphah International University | N/A |
| Unknown | Respiration in Chronic Low Back Pain NCT05718713 | Seda Saka | — |
| Completed | Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments NCT05578781 | University of Washington | N/A |
| Completed | A Feasibility Study of a Multidisciplinary Treatment for Patients with Chronic Low Back Pain: PAINDOC Study. NCT05974072 | University of Barcelona | N/A |
| Unknown | Risk and Protective Factors in Multimodal Pain Therapy in Patients With Chronic Lumbal Pain NCT04881188 | Ruhr University of Bochum | — |
| Unknown | The Use of Pressure Sensors in Functional Assessment and Treatment of Low Back Pain Patients NCT05696249 | Charles University, Czech Republic | N/A |
| Unknown | Comparison of Swiss Versus Standard Low Back Acupuncture in Patients With Chronic Low Back Pain NCT05232487 | Li Yiming | N/A |
| Completed | Manual Therapy Plus Capacitive and Resistive Electric Transfer Therapy in Individuals With Chronic Low Back Pa NCT05680467 | International Hellenic University | N/A |
| Unknown | Does the Therapist's Assessment of Movement Control in Low Back Pain Patients Correspond to an Objective Kinem NCT05511012 | University Hospital, Brest | N/A |
| Unknown | Pain Types and Pain Severity in Chronic Low Back Pain NCT05604027 | Konya Beyhekim Training and Research Hospital | — |
| Completed | A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain NCT05630196 | Eli Lilly and Company | Phase 2 |
| Completed | Comparison of the Effects of Instrument Assisted Soft Tissue Mobilization Techniques Low Back Pain NCT05623735 | Eastern Mediterranean University | N/A |
| Completed | Vertical Climbing (CLMBR) Exercise for Chronic Low Back Pain NCT05483608 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain NCT05823857 | Concordia University, Montreal | N/A |
| Completed | Virtual Reality-based Induction to Improve Positive Body Image in Low Back Pain Patients. NCT06054074 | University of Valencia | N/A |
| Unknown | Effectiveness of Pressure Biofeedback Therapy and Progressive Muscle Relaxation Technique in Improving Pain an NCT05616702 | Dow University of Health Sciences | N/A |
| Completed | Exercise-based Telerehabilitation Program for Police Officers and Firefighters With Chronic Non-specific Low B NCT05481996 | Federal University of Pelotas | N/A |
| Unknown | The ECEALT Chronic Low Back Pain Study NCT05040633 | Health Rehab and Research Clinic | N/A |
| Completed | The BEST Trial: Biomarkers for Evaluating Spine Treatments NCT05396014 | University of North Carolina, Chapel Hill | Phase 4 |
| Unknown | Ankle Spine Syndrome "RAFFET Syndrome II NCT06140862 | Noha Khaled Shoukry | N/A |
| Completed | Motivation and Adherence to Exercise Recommendations NCT05512338 | Brno University Hospital | N/A |
| Recruiting | "Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2) NCT05508360 | Spinal Stabilization Technologies | N/A |
| Completed | Evolution of Physical Activity, Sedentary Behavior and Associated Motivations After Rehabilitation for Chronic NCT05404854 | Centre Hospitalier Universitaire de Nīmes | — |
| Unknown | High Intensity Training to Improve Diaphragm Functioning in Persons With Chronic Nonspecific Low Back Pain NCT05384457 | Hasselt University | N/A |
| Completed | Rage Against the Pain to Address Chronic Low Back Pain Among Veterans NCT05103475 | VA Office of Research and Development | N/A |
| Unknown | Effects of Pain Neuroscience Education With Conventional Physical Therapy in Patients With Chronic Low Back Pa NCT05680506 | Foundation University Islamabad | N/A |
| Recruiting | Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain NCT05265000 | University of California, San Francisco | N/A |
| Completed | Self-Management of Chronic Low Back Pain: Targeting Patient Activation NCT06236529 | Johns Hopkins University | N/A |
| Active Not Recruiting | Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study NCT07008924 | University of Kansas Medical Center | — |
| Unknown | The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catast NCT05571215 | High Point University | N/A |
| Completed | Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain NCT04494698 | MMJ Labs LLC | N/A |
| Unknown | Functional Rehabilitation With HUBER Platform in the Treatment of Non-specific Chronic Low Back Pain. NCT05437016 | Thibaut Guiraud | N/A |
| Completed | MEPS-Pain: Personalized Pain Self-management Planning by and for Veterans Pilot Study NCT04075487 | VA Office of Research and Development | N/A |
| Recruiting | Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response NCT04142177 | VA Office of Research and Development | N/A |
| Unknown | Neurophysiological Assessment of Spinal Excitability in Chronic Low Back Pain NCT05402904 | Sohag University | N/A |
| Completed | Methylglyoxal Evaluation in Humans NCT05350553 | University of Kansas Medical Center | — |
| Completed | The Role of Balneotherapy in Older Adults With Chronic Low Back Pain NCT05078008 | Termalistur - Termas de Sao Pedro do Sul, E.M., S.A. | N/A |
| Completed | Time Course Effects of Functional Resistance Training on Fitness and Quality of Life Chronic Low Back Pain Pat NCT05449262 | Riphah International University | N/A |
| Recruiting | High Frequency RF Current Effects on Muscle Pain and Function NCT05345015 | Aristotle University Of Thessaloniki | N/A |
| Unknown | The Effect of Structured Pain Education on Pain and Performance Parameters in Patients With Chronic Low Back P NCT05331274 | Medipol University | N/A |
| Completed | Is Hip Range of Motion Relevant in the Treatment of Chronic Low Back Pain? NCT05328063 | University of Jaén | N/A |
| Completed | Addressing Health Disparities in Chronic Low Back Pain With Patient-Clinician Relatedness NCT05580380 | NYU Langone Health | N/A |
| Completed | Effect of Diaphragm Manual Therapy With Conventional Physical Therapy in Chronic Non-Specific Low Back Pain Pa NCT05299216 | University of Faisalabad | N/A |
| Completed | Effect of Segmental Control Program on Hamstring Peak Torque in Patients With Non-specific Low Back Pain NCT05288946 | Cairo University | N/A |
| Completed | Muscle Energy Technique and Foam Roller Self Myofascial Release in Two-wheeler Riders With Chronic Low Back Pa NCT06017804 | King Saud University | N/A |
| Completed | Locomotion Strategies of Low Back Pain Patients NCT05337995 | University of Rennes 2 | — |
| Completed | The Effect of Radiofrequency of 448 kHz on Pain and Function NCT05682287 | University of Applied Health Sciences | N/A |
| Active Not Recruiting | EFFects of EXPosure and Cognitive-behavioural Therapy for Chronic BACK Pain NCT05294081 | University of Kaiserslautern-Landau | N/A |
| Unknown | Investigating the Hypoalgesic Effects of Manipulative Therapy Using Pain Conditioning and Expectations in Low NCT05202704 | Universidade Federal de Sao Carlos | N/A |
| Completed | CLBP Single-Arm Long-Term Follow-up Study NCT05207813 | Boston Scientific Corporation | — |
| Unknown | Technology Supported High Intensity Training at Home for Persons With Chronic Low Back Pain NCT05234008 | Hasselt University | Phase 3 |
| Completed | Movement Control Exercises With and Without Specific Breathing Techniques for the Treatment of Chronic Low Bac NCT05268822 | Kuopio University Hospital | N/A |
| Completed | Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain NCT05085782 | Université de Sherbrooke | Phase 2 |
| Completed | Turkish Validity and Reliability of the UW Concerns About Pain Scale NCT05201716 | Kutahya Health Sciences University | — |
| Completed | The Effects of Dance Therapy in Women With Chronic Low Back Pain NCT05301491 | Hasan Kalyoncu University | N/A |
| Active Not Recruiting | EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain NCT05263037 | AppliedVR Inc. | N/A |
| Completed | Descriptive Pilot Study of the Effects of a Standardized Neuromodulation Program on Cortical Brain Function in NCT03929952 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | The Effects of Self-Natural Posture Exercise Programs on Chronic Low Back Pain NCT05136729 | Billings Clinic | N/A |
| Completed | Interferential Current Treatment Reduces Low Back Pain and Improves Functionality in Patients With Chronic Low NCT05843136 | Universidade Federal do Oeste do Para | N/A |
| Unknown | Foot Spine Syndrome "RAFFET Syndrome" NCT06180408 | Noha Khaled Shoukry | N/A |
| Completed | PET/CT Guided Robotic Arm-assisted Pain Palliation in Chronic Nociceptive Low Backache NCT05560165 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Withdrawn | Post Market Observational Trial for the PerQdisc Nucleus Replacement Device NCT05105490 | Spinal Stabilization Technologies | — |
| Completed | Postoperative Telehealth Mindfulness Intervention After Spine Surgery NCT04648683 | Vanderbilt University Medical Center | N/A |
| Completed | Mechanisms of Chiropractic Spinal Manipulation for Chronic Low Back Pain NCT05162924 | Real Centro Universitario Maria Cristina | N/A |
| Active Not Recruiting | Development and Feasibility of Mindfulness Based Pain Reduction NCT04980612 | University of California, San Francisco | N/A |
| Unknown | Chronic Low Back Pain - Epiduroscopy Treatment NCT03916666 | Pavol Jozef Safarik University | — |
| Completed | Effectiveness Analysis of Ultrasound-guided Intratissue Percutaneous Electrolysis (EPI) in Patient With Chroni NCT04290221 | Universidad de Almeria | N/A |
| Completed | Biopsychosocial vs Multimodal Chronic Pain Management NCT07406711 | Osijek University Hospital | N/A |
| Completed | Osteopathic Single CAse Research for Patients With Chronic Low Back Pain NCT05120921 | University College of Osteopathy | N/A |
| Completed | Comparative Effects of Muscle Energy Technique and Routine Physical Therapy on Quadratus Lumborum in Patients NCT05174520 | University of Lahore | N/A |
| Completed | Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Chronic Low Back Pain NCT05086289 | Eli Lilly and Company | Phase 2 |
| Completed | The Effect of Exercise Applied With Stretching Platform in Patients With Chronic Low Back Pain NCT05726955 | Istanbul University - Cerrahpasa | N/A |
| Completed | Correlation Between Posterior Oblique Sling Activation and Contralateral Glenohumeral Stability in Low Back Pa NCT05050695 | Shaimaa Ramadan Ibrahim Abdul-ghani El Deab | — |
| Completed | Evaluation of Long-Term Continuity of Exercises in Low Back Pain Individuals NCT04824547 | Hacettepe University | N/A |
| Completed | Lumbopelvic Manipulation Effects on Fatigue in Chronic Low Back Pain Patients NCT05282589 | Riphah International University | N/A |
| Active Not Recruiting | A First in Human Feasibility Study to Evaluate the Safety and Effectiveness of the BIOTRONIK Prospera SCS Syst NCT04683718 | Biotronik, Inc. | N/A |
| Completed | Immediate Effects of Two Spinal Manipulative Techniques NCT05057091 | Alanya Alaaddin Keykubat University | N/A |
| Completed | Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain NCT04849429 | Dr. Himanshu Bansal Foundation | Phase 1 |
| Unknown | Essential Oil for Chronic Low Back Pain NCT05021146 | Buda Health Center | N/A |
| Completed | Deep Tissue Massage in Office Workers With Chronic Low Back Pain NCT05690178 | Poznan University of Physical Education | N/A |
| Unknown | Efficacy of Passive Joint Mobilization vs Mobilization With Movement on Pain Processing in Patients With Chron NCT04940715 | Universidad Rey Juan Carlos | N/A |
| Completed | Swimming Versus Standard Physiotherapy Care as Rehabilitation Modalities for Persistent Low Back Pain: Feasibi NCT06423755 | Canterbury Christ Church University | N/A |
| Unknown | Effectiveness of Treadmill Walk on Chronic Low Back Pain NCT05102097 | Bayero University Kano, Nigeria | N/A |
| Completed | The Effects of Immersion in 42℃ Thermal-mineral Water on Chronic Low-back Pain NCT05342051 | Polyclinic of the Hospitaller Brothers of St. John of God, Budapest | N/A |
| Completed | Acupuncture for Chronic Low Back Pain in Older Adults NCT04982315 | Kaiser Permanente | N/A |
| Completed | Goal Oriented Activity for Latinos With Spine Pain NCT05005416 | San Diego State University | N/A |
| Withdrawn | Comparison of Continuous and Burst High Frequency Spinal Cord Stimulation Paradigms NCT04709757 | Rush University Medical Center | N/A |
| Completed | Breathing and Attention Training for Chronic Low Back Pain NCT04740710 | University of Florida | Phase 1 / Phase 2 |
| Completed | ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation NCT04803214 | Mainstay Medical | N/A |
| Completed | The Effect of Mulligan Mobilization Technique on Balance, Pain and Functionality in Patients With Chronic Low NCT05334394 | Medipol University | N/A |
| Completed | Effectiveness and Safety of Pharmacopunture Therapy for Chronic Low Back Pain: A Pragmatic Randomized Controll NCT04833309 | Jaseng Medical Foundation | N/A |
| Completed | The Back Pain Consortium Research Program Study NCT04870957 | University of Michigan | Phase 4 |
| Completed | Digital Care Program for Chronic Low Back Pain NCT04808141 | Sword Health, SA | N/A |
| Completed | Mind Your Pain: Validating a Mindful Interoceptive Exposure Task for Patients With Chronic Low Back Pain NCT06186193 | University of California, San Francisco | — |
| Completed | Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain NCT04874636 | Eli Lilly and Company | Phase 2 |
| Unknown | Cognitive Functional Therapy Compared With Sham-treatment for Low Back Pain NCT04518891 | University of Sao Paulo | N/A |
| Recruiting | DBS of the SCC for the Treatment of Medically Refractory CLBP NCT04085406 | University of California, Los Angeles | N/A |
| Completed | Personalized Auricular Vagus Nerve Stimulation in Intractable Chronic Low Back Pain NCT04753528 | Aurimod GmbH | N/A |
| Completed | Ultrasound-Guided Lumbar Facet Joint Injections for Facet-Related Pain: A Randomized Comparison of Saline, Ste NCT07528794 | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | N/A |
| Completed | Yoga and Mantram for Chronic Pain and PTSD NCT03816007 | VA Office of Research and Development | N/A |
| Completed | Treating Negative Affect in Low Back Pain Patients NCT04747314 | Ajay Wasan, MD, Msc | Phase 2 / Phase 3 |
| Recruiting | Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar I NCT05066334 | Fondazione Policlinico Universitario Campus Bio-Medico | Phase 2 |
| Completed | Effects of a Myofascial Technique on Biomechanical Properties of the Lumbar Myofascia of Chronic Low Back Pain NCT04830566 | Université de Sherbrooke | N/A |
| Completed | Evaluation of The Immediate Effect of Myofascial Release Application in Patients With Chronic Low Back Pain NCT05302882 | Halic University | N/A |
| Terminated | Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department NCT04783532 | Vanderbilt University Medical Center | N/A |
| Unknown | A Study on the Effectiveness of Tuina in Managing Chronic Low Back Pain NCT05363579 | Singapore General Hospital | N/A |
| Unknown | Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain NCT04803149 | Avanos Medical | N/A |
| Completed | To Observe the Effect of Sphinx Pose (Salamba Bhujangasana) Among Health Care Providers With Chronic Low Back NCT04721639 | University of Karachi | N/A |
| Completed | Effectiveness of Cat-Cow Yoga in Managing Chronic Low Back Pain NCT04723225 | University of Karachi | N/A |
| Recruiting | Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain NCT04658628 | University of California, Los Angeles | — |
| Completed | Lower Back Biomechanics in Veterans With Non-Specific Low Back Pain NCT04249453 | VA Office of Research and Development | — |
| Completed | EaseVRx for the Reduction of Chronic Pain and Opioid Use NCT04139564 | AppliedVR Inc. | N/A |
| Completed | Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block NCT04658953 | Centre Hospitalier Universitaire Saint Pierre | N/A |
| Completed | Persistent Post-Lumbar Surgery Pain Syndrome (PSPS) Type II is a Common Condition Encountered in Pain Units, W NCT07156513 | Puerta de Hierro University Hospital | N/A |
| Completed | EuroPainClinicsStudy IX ( EPCS IX ) NCT07411950 | EPC Education s.r.o. | N/A |
| Active Not Recruiting | Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure NCT05463367 | Northwestern University | Phase 2 |
| Completed | Effects of the COVID-19 Pandemic on Fibromyalgia Patients NCT04730934 | Kars State Hospital | — |
| Recruiting | Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropa NCT04730700 | University of Kansas Medical Center | N/A |
| Completed | Comparing the Effect of Chiropractic Manipulation and Spinal Decompression Device Treatment NCT05460286 | Mustafa AĞRAŞ | N/A |
| Completed | Does Low Back Position Matters in Manual Therapy Treatment NCT04664348 | University of Jaén | N/A |
| Completed | EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines NCT04607460 | Brigham and Women's Hospital | N/A |
| Completed | Effects of Basic Body Awareness Therapy on Pain, Sleep, Disability and Quality of Life in Chronic Low Back Pai NCT05080101 | Hacettepe University | N/A |
| Completed | The Effect of Telerehabilitation in Patients With Chronic Low Back Pain NCT04567758 | Marmara University | N/A |
| Completed | The Effect of Physiotherapy on Chronic Low Back Pain NCT06234891 | Kayseri City Hospital | N/A |
| Terminated | The Effect of Reducing Sedentary Behaviour in Comparison to Promoting Physical Activity on Chronic Non-specifi NCT04610905 | Vrije Universiteit Brussel | N/A |
| Completed | PCT of Pharmacopuncture Therapy for Chronic Low Back Pain : A Pilot Study NCT04576520 | Jaseng Medical Foundation | N/A |
| Completed | Physical Activity Interventions To Heal Chronic Low Back Pain NCT04678297 | University of Connecticut | N/A |
| Completed | COgNitive FuncTional Therapy+ for Chronic Low Back paIn NCT04399772 | Odense University Hospital | N/A |
| Completed | Combining Non-invasive Brain Stimulation and Exercise to Treat Low Back Pain NCT04555278 | Hugo Massé-Alarie | N/A |
| Completed | Evaluation of Safety, Tolerability, and Efficacy of CordSTEM-DD in Patients With Chronic Low Back Pain NCT04530071 | CHABiotech CO., Ltd | Phase 1 / Phase 2 |
| Completed | Virtual Reality Therapy for Chronic Low Back Pain NCT04409353 | Cedars-Sinai Medical Center | N/A |
| Completed | A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain NCT04283370 | Universidad de Almeria | N/A |
| Completed | Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain NCT04529096 | Eli Lilly and Company | Phase 2 |
| Active Not Recruiting | Efficacy of Spinal Manipulation Therapy or Mindfulness-based Reduction Therapy on Patients With Chronic Low Ba NCT04744883 | Rush University Medical Center | EARLY_Phase 1 |
| Completed | Fascial-muscular Lengthening Therapy in the Patients With Chronic Low Back Pain. NCT04760366 | Riphah International University | N/A |
| Completed | Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT) NCT04479787 | Abbott Medical Devices | N/A |
| Unknown | From Structural to Functional Characteristics of the Lumbar Multifidus in Low Back Pain NCT03612089 | KU Leuven | — |
| Completed | Immediate Effect of Hamstring Stretching in Patients With Chronic Low Back Pain NCT04551326 | University Hospital, Clermont-Ferrand | N/A |
| Completed | VANISH for Chronic Low Back Pain NCT04236804 | Ajay Wasan, MD, Msc | N/A |
| Unknown | Confinement Effect on Low Back Pain Intensity in Chronic Low Back Pain Patients NCT04406363 | University Hospital, Angers | — |
| Completed | Online Physical Exercise for Chronic Low Back Pain NCT05895630 | Mathieu Roy | N/A |
| Completed | Electrical Stimulation With Interferential Current in the Non-especific Chronic Low Back Pain: Effects on the NCT04483128 | University of Seville | N/A |
| Completed | Efficacy of Electrical Dry Needling in Pain, Sensitivity, Functionality and Quality of Life of Patients With C NCT04804228 | Universidad de Almeria | N/A |
| Completed | E-lombactifs: Evaluation of the Impact a Smartphone Application on Adherence an Exercise Program in Chronic Lo NCT04264949 | University Hospital, Clermont-Ferrand | N/A |
| Unknown | Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain NCT04786145 | University of Aarhus | N/A |
| Completed | Digital Therapeutics (DTx) for Pain: Pilot Study of a Virtual Reality Software for Chronic Pain NCT04225884 | Orion Corporation, Orion Pharma | N/A |
| Recruiting | A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Ch NCT05986292 | Eli Lilly and Company | Phase 2 |
| Terminated | Frequency of Correct Response and Factors Associated in the Medium Term With a Multimodal Rehabilitation Progr NCT04128098 | Centre Hospitalier Universitaire Dijon | — |
| Completed | Adaptability and Resilience in Aging Adults-2 NCT04068922 | University of Florida | N/A |
| Completed | Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain NCT04238676 | Persica Pharmaceuticals Ltd | Phase 1 / Phase 2 |
| Unknown | Feasibility Study on an Immersive Virtual Reality Tool in the Treatment of Chronic Low Back Pain NCT04781465 | Fondation Hôpital Saint-Joseph | N/A |
| Completed | Effectiveness of Pain Neuroscience Education Compared to a Conventional Education for Patients With Chronic Lo NCT04179708 | University Hospital, Lille | N/A |
| Completed | Mindfulness and Chronic Low Back Pain NCT03354585 | University of California, San Diego | N/A |
| Completed | Investigation of the Effects of Two Different Treatment Programs on Chronic Low Back Pain NCT04643756 | Pamukkale University | N/A |
| Unknown | Acupuncture on GB26 to Treat Chronic Low Back Pain NCT03987971 | Wenzhou Medical University | N/A |
| Completed | The Effects of Different Exercise Approaches in Patients With Chronic Low Back Pain NCT04000685 | Hacettepe University | N/A |
| Completed | Temporal and Kinematic Analysis of Timed Up and Go Test in Chronic Low Back Pain Patients NCT04588155 | Fondazione Don Carlo Gnocchi Onlus | — |