| Not Yet Recruiting | Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Compute NCT07477028 | Noah Tech, Corp. | — |
| Recruiting | Determining ICU Staffs Conceptions, Opinions, Views, Experiences and Reflection of Brain Death and Organ Donat NCT06640088 | University Hospital, Basel, Switzerland | — |
| Completed | Etiology and Hemodynamic Instability in Brain Death NCT06569992 | Antalya Training and Research Hospital | — |
| Not Yet Recruiting | Implementation of Apnoea Test for Patients With Suspected Brain Death NCT06359119 | Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged | — |
| Recruiting | Pupillometric Evaluation in Patients Declared Brain Dead - a Prospective Quality Control Study NCT06279975 | University Hospital, Basel, Switzerland | — |
| Completed | Validation of the Apnea Test Performed by High-flow Oxygen Therapy in Patients With Clinical Brain Death NCT05950178 | Centre Hospitalier Régional d'Orléans | N/A |
| Completed | ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea Test NCT06983990 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Completed | Research on the Brain Death Determination in China NCT05903443 | Xuanwu Hospital, Beijing | — |
| Active Not Recruiting | Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY) NCT05148715 | Université de Sherbrooke | Phase 2 |
| Unknown | Methods of Confirmation of Brain Death NCT04734574 | Brno University Hospital | — |
| Unknown | Incidence of Complications of Brain Death NCT04404972 | Brno University Hospital | — |
| Completed | Electrical Impedance Tomography Measurements During Apnea Test in Patients With Suspected Brain Death NCT04857242 | Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged | N/A |
| Unknown | Evaluation of CTA on the Assessment of Brain Death NCT04914039 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Completed | Intravenous Thyroxine for Heart-Eligible Organ Donors NCT04415658 | Washington University School of Medicine | Phase 3 |
| Unknown | Online Noninvasive Assessment of Human Brain Death and Deep Coma by Near-infrared Spectroscopy NCT04623294 | Chinese Academy of Medical Sciences | — |
| Completed | The Anticipated Organ Donation Approach NCT03765814 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | — |
| Completed | Brain Death Diagnosis at an Academic Tertiary Medical Care Center NCT03984981 | University Hospital, Basel, Switzerland | — |
| Unknown | Optical Assessment on Brain Death Via a Oxygen Supply Procedure NCT03864887 | Chinese Academy of Medical Sciences | — |
| Withdrawn | Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination NCT03743805 | Prisma Health-Midlands | EARLY_Phase 1 |
| Completed | The Use of Liraglutide in Brain Death NCT03672812 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Terminated | Goal of Open Lung Ventilation in Donors NCT03439995 | Vanderbilt University Medical Center | N/A |
| Unknown | "LiverColor": Machine Learning in Liver Photographs NCT05202886 | Hospital Vall d'Hebron | N/A |
| Completed | Resting Energy Needs in Brain Dead Patients (reSting EneRgy nEeds iN brAin DEad Patients) NCT05070182 | Aristotle University Of Thessaloniki | — |
| Unknown | Organ Donation Survey Among Health Care Professionals in Argentina NCT03458052 | Hospital Italiano de Buenos Aires | — |
| Completed | Cyclosporine a Pretreatment and Kidney Graft Function NCT02907554 | University Hospital, Clermont-Ferrand | Phase 4 |
| Completed | Therapeutic Hypothermia in "Expanded Criteria" Brain-dead Donors and Kidney-graft Function NCT03098706 | Nantes University Hospital | N/A |
| Completed | Deceased Organ Donor Interventions to Protect Kidney Graft Function NCT02525510 | University of California, San Francisco | N/A |
| Completed | Donation Network to Optimize Organ Recovery Study NCT03179020 | Hospital Moinhos de Vento | N/A |
| Completed | Neurophysiological Examination in Patients With Brain Death NCT03262896 | Yuzuncu Yil University | — |
| Completed | Orbital Artery Doppler Ultrasound in Brain Death NCT06229782 | Korgün Ökmen | N/A |
| Completed | Understanding Family Refusal NCT04303624 | Yale-NUS College | — |
| Completed | Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approac NCT02742857 | Bioquark Inc. | Phase 1 |
| Completed | Naloxone for Optimizing Hypoxemia Of Lung Donors NCT02581111 | Washington University School of Medicine | Phase 2 / Phase 3 |
| Completed | Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test? NCT02503813 | MemorialCare Health System | N/A |
| Completed | Apnea Tests as the Methods of Brain Death Diagnosis. NCT03281993 | Pomeranian Medical University Szczecin | — |
| Completed | Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain Death NCT02460250 | University Hospital, Limoges | N/A |
| Completed | Special Imaging Technique to Aid in the Diagnosis of Patients in Coma After Cardiac Arrest NCT02102945 | Nova Scotia Health Authority | N/A |
| Completed | Computed Tomography Angiography Accuracy in Brain Death Diagnosis NCT02045407 | Sergio Brasil, MD MSc | — |
| Completed | Cerebral Oximetry As an Auxiliary Diagnostic Tool in the Diagnosis of Brain Death NCT02741375 | Karadeniz Technical University | — |
| Completed | Organ Donor Tissue Oxygen Saturation as a Predictor of Number of Organs to Transplant Per Donor NCT01819116 | The Cleveland Clinic | — |
| Terminated | Pre-recovery Bedside Liver Biopsy in Brain Death Organ Donors NCT01810640 | Rutgers, The State University of New Jersey | N/A |
| Completed | Alterations of Conjunctival Microcirculation in Brain Dead Patients NCT02483273 | Lithuanian University of Health Sciences | — |
| Completed | Ex-Vivo Lung Perfusion to Increase the Number of Organs for Transplantation NCT01967953 | Policlinico Hospital | Phase 1 |
| Completed | Thyroid and Adrenocortical Hormone Replacement in Organ Donors NCT04528797 | Medical University of South Carolina | N/A |
| Completed | Nutritional Status and Enteral Absorption Capability After Brain Death NCT00858390 | The University of Texas Health Science Center, Houston | N/A |
| Terminated | Organ Donation and Hydrocortisone Treatment NCT00675272 | Kuopio University Hospital | N/A |
| Completed | Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit NCT00808691 | National Taiwan University Hospital | — |
| Completed | The Effect of Nebulized Albuterol on Donor Oxygenation NCT00310401 | Vanderbilt University Medical Center | Phase 2 |
| Completed | N-acetyl-cysteine (NAC) and Kidney Graft Function NCT00998972 | Institut d'Anesthesiologie des Alpes Maritimes | Phase 3 |
| Completed | Thyroxine Replacement in Organ Donors NCT00238030 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 1 / Phase 2 |
| Completed | Brain Death: Inflammatory Response, Apoptosis, and Endotoxin Tolerance NCT00615225 | Delafontaine Hospital | — |