NCT03179020

Donation Network to Optimize Organ Recovery Study

Cluster Randomized Trial Evaluating the Implementation of a Evidence Based Checklist for the Management of Potential Organ Donors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,535 (actual)
• Sponsor: Hospital Moinhos de Vento · Academic / Other
• Sex: All
• Age: 14 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study consists in an cluster-randomized clinical trial involving near 60 Brazilian intensive care units (ICUs) with a high notification rate of potential donors of organs and tissues. ICUs will be randomized in a 1:1 ratio to manage potential organ donors through the use of a evidence-based checklist or to manage potential organ donors according usual care. The primary outcome is the rate of losses of potential donors due to cardiac arrest. Secondary outcome measures include number of effective organ donors and number of organs recovery per effective donor. The first subject was enrolled on June 20, 2018.

Conditions

• Brain Death
• Organ Donation

Interventions

Type	Name	Description
OTHER	Checklist use	Management of the potential donor guided by the use of an evidence-based checklist. This checklist is based on main recommendations of the Brazilian guideline for the management of potential multiple organ donors.
OTHER	Usual care	Management of the potential donor according usual care.

Timeline

• Start date: 2017-06-20
• Primary completion: 2019-08-28
• Completion: 2019-08-28
• First posted: 2017-06-07
• Last updated: 2020-11-02

Locations

63 sites across 1 country: Brazil