NCT04857242

Electrical Impedance Tomography Measurements During Apnea Test in Patients With Suspected Brain Death

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged · Other Government
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Apnea testing is the final decisive examination in the strictly regulated process of brain death assessment. There is no standardized method found in the literature for apnea testing except for the inspection of possible spontaneous chest movements. In addition, the test itself lasts for several minutes leading to the collapse of the lungs. Electrical impedance tomography (EIT) is a non-invasive, real-time monitoring technique, which is suitable for detecting changes in lung volumes during ventilation. With its help, one can examine the spontaneous initiation of inspiration, the development of atelectasis and the reopening of collapsed regions by mechanical ventilation. Furthermore, the apnea test provides for analysing the effect of changes in pulmonary perfusion on impedance in the absence of noise generated by ventilation.

Detailed description

The aim of the study is to assess the eligibility of electrical impedance monitoring for the detection of possible spontaneous initiations of inspiration during apnea test in patients with suspected brain death. The study could contribute to the opening of new areas in the clinical use of the electrical impedance device. An additional aim is to observe the collapse and the reopening by recruitment manoeuvers of different pulmonary regions.

Conditions

• Brain Death

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Apnea test, alveolar recruitment	Alveolar recruitment following the phase of apnea testing

Timeline

• Start date: 2021-04-01
• Primary completion: 2023-04-13
• Completion: 2023-04-13
• First posted: 2021-04-23
• Last updated: 2024-02-20

Locations

1 site across 1 country: Hungary