| Not Yet Recruiting | Sensory Substitution and Brain Plasticity Following Vision Loss NCT07450677 | Stanford University | N/A |
| Enrolling By Invitation | Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmi NCT07529041 | University Medical Center Goettingen | N/A |
| Recruiting | Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) NCT06891443 | Laboratoires Thea | Phase 3 |
| Not Yet Recruiting | Validation of Texture Changing Coatings for Use in At-Home Rapid Tests NCT06539728 | University of Delaware | N/A |
| Unknown | iReach: a Rehabilitative Medical Device NCT06334614 | Istituto Italiano di Tecnologia | N/A |
| Recruiting | Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases NCT06070467 | University Hospital, Strasbourg, France | — |
| Recruiting | Visual Involvement in Giant Cell Arteritis NCT06500728 | ASST Fatebenefratelli Sacco | — |
| Enrolling By Invitation | The Impact of the Years of Blindness on Sleep and Dreaming Processes and the Relationships With Spatial Abilit NCT06631807 | Istituto Italiano di Tecnologia | — |
| Unknown | Sleep Profile of Patients With Septo-optic Dysplasia NCT06262152 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis NCT06451172 | Eye & ENT Hospital of Fudan University | EARLY_Phase 1 |
| Unknown | Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study. NCT05806684 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | — |
| Completed | The Effect of Social Skills Training in Visually Impaired Adolescents NCT05608811 | Saglik Bilimleri Universitesi | N/A |
| Unknown | Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment NCT05377853 | Smith-Kettlewell Eye Research Institute | N/A |
| Completed | Implicit Attitudes Toward Body Shape Among Blind Women NCT05144906 | University of Haifa | — |
| Recruiting | Testing Tactile Aids With Blind Subjects NCT06237829 | University of Delaware | N/A |
| Completed | Assessment of the Validity, Reliability, and Feasibility of Two Smartphone Applications for Testing the Visual NCT04936100 | Shahid Beheshti University of Medical Sciences | N/A |
| Unknown | MySpace: the Role of Vision in Representing Space NCT06364605 | Istituto Italiano di Tecnologia | N/A |
| Unknown | An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerabil NCT04855045 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Unknown | Evaluation of the Efficacy of the BrainPort Vision Pro on the Performance of Daily Activities in the Profoundl NCT04725760 | Wicab | N/A |
| Completed | Physical Activity and Sports for People With Visual Impairments NCT06318000 | Józef Piłsudski University of Physical Education | — |
| Recruiting | Development of a Cortical Visual Neuroprosthesis for the Blind NCT02983370 | Universidad Miguel Hernandez de Elche | N/A |
| Terminated | Extension Study to Study PQ-110-001 (NCT03140969) NCT03913130 | Laboratoires Thea | Phase 1 / Phase 2 |
| Active Not Recruiting | A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in NCT03913143 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Completed | Collision Warning Device for Blind and Visually Impaired NCT03057496 | Massachusetts Eye and Ear Infirmary | N/A |
| Completed | Natural History Study of CEP290-Related Retinal Degeneration NCT03396042 | Editas Medicine, Inc. | — |
| Recruiting | Stem Cell Ophthalmology Treatment Study II NCT03011541 | MD Stem Cells | N/A |
| Unknown | A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury NCT02393118 | Wicab | N/A |
| Terminated | Visual Information Restoration and Rehabilitation Via Sensory Substitution Technology in Children NCT03002597 | Ellen Mitchell | N/A |
| Completed | Ocular Manifestations in Rheumatic Diseases NCT03753893 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Wayfinding Information Access System for People With Vision Loss NCT00829036 | US Department of Veterans Affairs | N/A |
| Completed | Prevalence of Blindness, Visual Impairment in Chao Nan Area, China NCT04143334 | Chinese University of Hong Kong | — |
| Unknown | Neuroplasticity in Blind Subjects After Repetitive Tactile Stimulation NCT01754103 | Universidad Complutense de Madrid | N/A |
| Completed | Computer Vision System for the Blind Veteran NCT00920231 | VA Office of Research and Development | Phase 1 |
| Completed | Workshops for Veterans With Vision and Hearing Loss NCT01109576 | US Department of Veterans Affairs | EARLY_Phase 1 |
| Completed | A Study to Evaluate the BrainPort® Vision Device in Subjects Who Are Blind NCT01488786 | Wicab | N/A |
| Completed | Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulati NCT02643238 | Akron Children's Hospital | N/A |
| Unknown | Multisensory Body and Space Representations (BASES-EXTINCTION) NCT03201341 | Hospices Civils de Lyon | N/A |
| Terminated | Melatonin Studies of Totally Blind Children NCT00795236 | Oregon Health and Science University | N/A |
| Completed | Virtual Reality Mobility Training System for Veterans With Vision Loss NCT00333879 | US Department of Veterans Affairs | N/A |
| Withdrawn | Functional Neuroimaging of Cortical Plasticity in the Human Visual System NCT01062672 | Baylor College of Medicine | — |
| Terminated | Emergency Egress and Information System for Persons With Vision Loss NCT00262509 | US Department of Veterans Affairs | N/A |
| Completed | Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone NCT00875043 | Rutgers, The State University of New Jersey | — |
| Completed | Pars Plana Surgical Capsulotomy for Posterior Capsular Opacification NCT00964613 | Dow University of Health Sciences | — |
| Completed | Effects of Sevoflurane and Propofol on Light Flashed Evoked Pupillometry NCT01219569 | Rutgers, The State University of New Jersey | — |
| Unknown | Do Blue-Blocking Lenses Block Blue Colour From Our Lives? NCT00403143 | London North West Healthcare NHS Trust | N/A |
| Completed | Use of "Smart Wheelchairs" to Provide Independent Mobility to Visual and Mobility Impairments NCT00333762 | VA Office of Research and Development | N/A |
| Completed | Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects NCT00972075 | Neurim Pharmaceuticals Ltd. | Phase 2 |
| Terminated | Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity NCT00634972 | University of South Alabama | Phase 4 |
| Terminated | Young Blind Child Melatonin Treatment Study NCT00688935 | Oregon Health and Science University | N/A |
| Terminated | Blind Elderly Melatonin Treatment Study NCT00692094 | Oregon Health and Science University | N/A |
| Completed | Enhanced Tactile Memory in the Blind NCT00076700 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Brain Plasticity of Verbal Memory in the Blind NCT00059189 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Terminated | Blind Child Melatonin Treatment Study NCT00691444 | Oregon Health and Science University | N/A |
| Completed | Healthy Volunteer Study of Sildenafil Effects Upon Vision NCT00251784 | University of Cambridge | Phase 4 |
| Completed | Evaluation of Eye Movement Tracking Systems for Visual Rehabilitation NCT00013429 | US Department of Veterans Affairs | Phase 2 |
| Completed | The Connection Between Areas in the Brain of Blind Patients NCT00001926 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | The Impact of Rehabilitation on Quality of Life in Visually Impaired NCT00013403 | US Department of Veterans Affairs | Phase 2 |
| Terminated | Melatonin for Circadian Sleep Disorders in the Blind NCT00911053 | Oregon Health and Science University | N/A |
| Completed | Mechanisms of Human Plasticity in the Human System NCT00001661 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Long Term Follow-Up of Diabetic Retinopathy NCT00001395 | National Eye Institute (NEI) | — |
| Completed | Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity NCT01203436 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Completed | Early Treatment Diabetic Retinopathy Study (ETDRS) NCT00000151 | National Eye Institute (NEI) | Phase 3 |
| Completed | Diabetic Retinopathy Study (DRS) NCT00000160 | National Eye Institute (NEI) | Phase 3 |