| Recruiting | Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas NCT07155525 | Minia University | Phase 3 |
| Not Yet Recruiting | Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable H NCT07030140 | Jinbo Yue | Phase 2 |
| Not Yet Recruiting | A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors NCT07036185 | Shanghai Bao Pharmaceuticals Co., Ltd. | Phase 1 |
| Not Yet Recruiting | Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract NCT06274879 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Not Yet Recruiting | Utidelone Capsule Monotherapy for Patients with Advanced Solid Tumors NCT06730581 | Beijing Biostar Pharmaceuticals Co., Ltd. | Phase 2 |
| Recruiting | A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in NCT05849480 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Recruiting | EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope NCT06340620 | Orlando Health, Inc. | N/A |
| Recruiting | Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers NCT06048133 | Nataliya Uboha | Phase 2 |
| Unknown | Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors NCT06256055 | UTC Therapeutics Inc. | Phase 1 |
| Recruiting | Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE) NCT06277531 | Peking University Third Hospital | — |
| Recruiting | Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949 | Beth Israel Deaconess Medical Center | Phase 2 |
| Not Yet Recruiting | Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma NCT06175845 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Looking At Bile Duct Cancer Patient Experience Patterns in Medical Trials NCT05706974 | Power Life Sciences Inc. | — |
| Active Not Recruiting | A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid NCT05712356 | Lisata Therapeutics, Inc. | Phase 2 |
| Recruiting | A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid T NCT06043466 | Chongqing Precision Biotech Co., Ltd | Phase 1 |
| Active Not Recruiting | Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors NCT05858736 | OncoC4, Inc. | Phase 1 |
| Enrolling By Invitation | Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Ca NCT06076252 | Affiliated Hospital of Guangdong Medical University | N/A |
| Unknown | Combined Treatment of Treated Bile Duct Cancer NCT05911425 | Zhejiang Cancer Hospital | Phase 2 |
| Recruiting | A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Seque NCT06028724 | Centro di Riferimento Oncologico - Aviano | — |
| Recruiting | Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma NCT05519319 | First People's Hospital of Hangzhou | N/A |
| Recruiting | Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointesti NCT05277766 | University Hospital, Ghent | Phase 1 |
| Recruiting | PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metast NCT05286814 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adu NCT05346484 | Imugene Limited | Phase 1 |
| Terminated | Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With NCT04566133 | National Cancer Institute (NCI) | Phase 2 |
| Unknown | CH-EUS in Diagnosis of Inoperable Bile Duct Tumors NCT05418543 | Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor | N/A |
| Suspended | Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types NCT05000294 | University of Florida | Phase 1 / Phase 2 |
| Recruiting | Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes NCT04907643 | Cedars-Sinai Medical Center | N/A |
| Completed | A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumor NCT04853017 | Elicio Therapeutics | Phase 1 |
| Recruiting | Prognostic Factors in Periampullary Tumors and Cysts NCT05155878 | Umeå University | — |
| Recruiting | Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma NCT04993131 | Oslo University Hospital | N/A |
| Completed | The Registry of Oncology Outcomes Associated With Testing and Treatment NCT04028479 | Taproot Health | — |
| Active Not Recruiting | CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors NCT04660929 | Carisma Therapeutics Inc | Phase 1 |
| Recruiting | Spanish Registry of Digestive Tumours RETUD NCT06711211 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | — |
| Completed | Recurrence After Whipple's (RAW) Study NCT04596865 | University Hospital Plymouth NHS Trust | — |
| Terminated | Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors NCT04383210 | Elevation Oncology | Phase 2 |
| Completed | Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Ca NCT04164069 | Anne Noonan | Phase 1 |
| Unknown | FAPI PET for Response Evaluation and Prognosis Prediction in Liver and Biliary Cancer Patients Treated With PD NCT05662488 | Peking Union Medical College Hospital | — |
| Completed | Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines. NCT05266300 | University of Southern Denmark | — |
| Recruiting | AZD6738 Plus Durvalumab in Biliary Tract Cancer NCT04298008 | Seoul National University Hospital | Phase 2 |
| Active Not Recruiting | DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer NCT04298021 | Seoul National University Hospital | Phase 2 |
| Completed | Nutrition in Gastrointestinal Tumors NCT04476082 | University Medicine Greifswald | — |
| Withdrawn | Irreversible Electroporation of Unresectable Liver Tumors NCT04404647 | Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery | N/A |
| Active Not Recruiting | Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal Sten NCT06453590 | Region Stockholm | N/A |
| Completed | The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone NCT04763642 | State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital | N/A |
| Terminated | Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinoma NCT04076761 | Sunnybrook Health Sciences Centre | Phase 2 |
| Terminated | Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. NCT04152018 | Pfizer | Phase 1 |
| Unknown | A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain NCT04014478 | Shanghai Golden Leaf MedTec Co. Ltd | N/A |
| Unknown | Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management St NCT03951324 | Innovative Digestive Health Education and Research Inc | — |
| Unknown | Metal Stents (Moving Cell Stent) for Inoperable Tumors of the Bile Duct Tract NCT03788655 | Johannes Vermehren | — |
| Completed | Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Ge NCT03602079 | Klus Pharma Inc. | Phase 1 / Phase 2 |
| Unknown | Percutaneous Hepatic Perfusion vs. Cisplatin/Gemcitabine in Patients With Intrahepatic Cholangiocarcinoma NCT03086993 | Delcath Systems Inc. | Phase 2 / Phase 3 |
| Unknown | PTFE Stents for Treatment of Malignant Biliary Strictures NCT03763214 | Johannes Vermehren | N/A |
| Completed | Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in NCT03111732 | National Cancer Institute (NCI) | Phase 2 |
| Unknown | Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program NCT03475966 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 NCT03058289 | Intensity Therapeutics, Inc. | Phase 1 / Phase 2 |
| Completed | Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies NCT03525067 | Central Hospital, Nancy, France | — |
| Completed | Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemo NCT02853474 | Centre Oscar Lambret | Phase 3 |
| Unknown | Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticodu NCT02954302 | The First Affiliated Hospital of Xiamen University | N/A |
| Completed | A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With NCT02821754 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis NCT02841800 | National Taiwan University Hospital | N/A |
| Completed | Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry. NCT04937322 | Methodist Health System | — |
| Active Not Recruiting | Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) NCT02628067 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours NCT02591030 | Centre Hospitalier Universitaire de Saint Etienne | Phase 2 / Phase 3 |
| Completed | Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic NCT02375880 | Leap Therapeutics, Inc. | Phase 1 |
| Completed | Loop-tipped Guidewire in Selective Biliary Cannulation NCT02028845 | Ajou University School of Medicine | N/A |
| Recruiting | Integrated Cancer Repository for Cancer Research NCT02012699 | University of Nebraska | — |
| Completed | Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma NCT01954745 | Massachusetts General Hospital | Phase 2 |
| Recruiting | Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer NCT01915225 | National Cancer Institute (NCI) | — |
| Recruiting | Quebec Pancreas Cancer Study NCT04104230 | George Zogopoulos | — |
| Unknown | Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma NCT01755013 | Weill Medical College of Cornell University | Phase 2 / Phase 3 |
| Unknown | T-EUS for Gastrointestinal Disorders: A Multicenter Registry NCT01522573 | Weill Medical College of Cornell University | — |
| Unknown | Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry NCT01439698 | Weill Medical College of Cornell University | — |
| Unknown | Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders NCT01438385 | Weill Medical College of Cornell University | — |
| Terminated | Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantation NCT01151761 | Stanford University | Phase 2 |
| Completed | Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers NCT01134276 | Seoul National University Hospital | N/A |
| Unknown | A Randomized, Open, Prospective Clinical Research of Fluorouracil Implant to Improve Surgical Gallbladder Canc NCT01317069 | Simcere Pharmaceutical Co., Ltd | Phase 2 |
| Completed | Effects of Preoperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy NCT01256034 | Chiba University | Phase 4 |
| Completed | Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy NCT01256047 | Chiba University | Phase 4 |
| Completed | A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography( NCT00779688 | Mauna Kea Technologies | — |
| Unknown | Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer NCT01111591 | Seoul National University Hospital | Phase 4 |
| Suspended | Gemcitabine With Peptide Vaccine Therapy in Treating Patients With Bile Duct Cancer NCT00624182 | Akita University Hospital | Phase 1 |
| Completed | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms NCT01640522 | University of Pittsburgh | N/A |
| Terminated | Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers NCT00832637 | New Mexico Cancer Research Alliance | Phase 2 |
| Unknown | Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy NCT00809081 | Yonsei University | Phase 3 |
| Completed | Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction NCT00280709 | University Hospital, Linkoeping | Phase 4 |
| Completed | Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy NCT00639314 | Wakayama Medical University | N/A |
| Completed | Quality Of Life in Patients With Malignant Biliary Obstruction NCT00579865 | Memorial Sloan Kettering Cancer Center | — |
| Completed | Randomized Controlled Trial on Pancreatic Stent Tube in Pancreaticoduodenectomy NCT00628186 | Wakayama Medical University | N/A |
| Unknown | HAI Via Interventionally Implanted Port Catheter Systems NCT00356161 | Charite University, Berlin, Germany | Phase 2 |
| Completed | Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Can NCT00183846 | University of Southern California | Phase 1 |
| Completed | Outcomes and Prognostic Factors in Hepatopancreatoduodenectomy NCT06631352 | Seoul National University Hospital | — |
| Withdrawn | Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour Surgery NCT02446379 | Lightpoint Medical Limited | — |