NCT06631352

Outcomes and Prognostic Factors in Hepatopancreatoduodenectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

1. In biliary tract malignancies, achieving a microscopically clear resection margin (R0) is considered the only treatment for a cure. 2. Hepatopancreatoduodenectomy(HPD) has been considered a surgical option for patients with extensive bile duct or gallbladder cancer to achieve an R0 resection. 3. The associated high morbidity and mortality rates have prevented HPD from becoming a standard surgical procedure worldwide. 4. Over the past few decades, the understanding of the bile duct anatomy has significantly improved, and many methods have been developed to assess liver function and future remnant liver volume. 5. We aimed to evaluate the short- and long-term outcomes of HPD and to assess risk factors associated with survival, early recurrence, and major complications to better evaluate the potential of the procedure as a standard treatment.

Conditions

• Hepatopancreaticobiliary (HPB) Malignancy
• Gall Bladder Cancer
• Bile Duct Cancer
• Pancreatoduodenectomy
• Hepatectomy

Interventions

Type	Name	Description
OTHER	Hepatopancreatoduodenectomy	Pancreatoduodenectomy with liver resection

Timeline

• Start date: 2000-01-01
• Primary completion: 2023-12-31
• Completion: 2024-05-31
• First posted: 2024-10-08
• Last updated: 2024-10-08