NCT01256034

Effects of Preoperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy

Effects of Preoperative Immunonutrition on Infectious Complication and Th1/Th2 Differentiation in Patients Undergoing Pancreaticoduodenectomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Chiba University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether preoperative immunonutrition is effective on infectious complication and Th1/Th2 differentiation in patients with pancreaticoduodenectomy.

Detailed description

The investigators reported that preoperative immunonutrition improve the incidence of postoperative infectious complication in patients after pancreaticoduodenectomy, and modulation of Th1/Th2 differentiation may play important roles in this effect. Object of this study is to investigate the effects preoperative immunonutrition on incidence of postoperative infectious complication, and Th1/Th2 balance after pancreaticoduodenectomy.

Conditions

• Pancreatic Cancer
• Bile Duct Cancer

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral IMPACT	oral supplementation for 5 days (1L/day) before surgery of a formula enriched with arginine, omega-3 fatty acids, and RNA

Timeline

• Start date: 2009-05-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2010-12-08
• Last updated: 2012-10-23
• Results posted: 2012-10-23

Locations

1 site across 1 country: Japan