NCT00809081

Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy

A Prospective, Randomized Trial of Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 38 (estimated)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Pancreaticoduodenectomy is associated with a high incidence of postoperative complications. These postoperative complications could delay postoperative resumption of adequate oral intake. Clinical study on postoperative feeding after pancreaticoduodenectomy is very limited. Method of Nutritional support (Enteral feeding or total parenteral support)after pancreaticoduodenectomy is controversial. 1. To evaluate whether early enteral nutrition may be a suitable alternative to total parenteral nutrition 2. To evaluate whether enteral feeding improve nutritional status after pancreaticoduodenectomy

Detailed description

Pancreaticoduodenectomy is associated with a high incidence of postoperative complications. These postoperative complications could delay postoperative resumption of adequate oral intake. The use of TPN significantly increases postoperative complications, especially those associate with infections. However, method of Nutritional support (Enteral feeding or total parenteral support)after pancreaticoduodenectomy is controversial. 1. To evaluate whether early enteral nutrition may be decreased the postoperative complications 2. To evaluate whether enteral feeding improve nutritional status after pancreaticoduodenectomy 3. To determine the optimal method for postoperative nutritional support

Conditions

• Pancreas Cancer
• Bile Duct Cancer
• Ampulla of Vater Cancer

Interventions

Type	Name	Description
PROCEDURE	Enteral Feeding and Total Parental Support	Enteral Feeding : 20ml/hr on POD1 * Velocity is progressively increased by 20ml/d until full nutritional goal (25Kcal/Kg)

Timeline

• Start date: 2007-07-01
• Primary completion: 2009-06-01
• Completion: 2010-01-01
• First posted: 2008-12-16
• Last updated: 2008-12-16

Locations

1 site across 1 country: South Korea