Anhedonia

81 registered clinical trials studyying Anhedonia — 23 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Multimodal Differences in Effort-based Decision-Making in Depression NCT06648460	Georgia Institute of Technology	N/A
Not Yet Recruiting	A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents NCT07348666	Ksana Health	N/A
Active Not Recruiting	Positive Affect Treatment for Spanish-Speaking Individuals NCT07493369	Southern Methodist University	N/A
Not Yet Recruiting	Promoting Positive Emotions in Adolescents Using Positive Events Training: An Indicated Approach NCT07288541	KU Leuven	N/A
Recruiting	The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health NCT07319143	The University of Hong Kong	N/A
Recruiting	Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects NCT07490353	Medical University of Vienna	Phase 1
Active Not Recruiting	Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents NCT06665620	Ksana Health	N/A
Not Yet Recruiting	Long-term Follow-up of Depressive Disorders in Psychiatric Care NCT07078227	Region Skane	—
Recruiting	Ecological Momentary Intervention for Reward in Anhedonia NCT07155941	Philipps University Marburg	N/A
Recruiting	Get ActivE Study for At-risk Youth NCT06829953	University of Pittsburgh	N/A
Recruiting	Stress Trajectories and Anhedonia in Adolescence Research Study NCT07040449	University of North Carolina, Chapel Hill	N/A
Recruiting	TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and A NCT06364488	BlueSkeye AI	N/A
Recruiting	Reward Processing and Exposure Therapy for Social Anxiety Disorder NCT06776991	University of California, Los Angeles	N/A
Terminated	A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Maj NCT06635135	Janssen Research & Development, LLC	Phase 3
Recruiting	A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide NCT05920252	Ksana Health	N/A
Active Not Recruiting	Psilocybin for Treatment-Resistant Depression NCT06230757	University of Colorado, Denver	Phase 2
Terminated	A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) W NCT06514742	Janssen Research & Development, LLC	Phase 3
Recruiting	Psychotherapy Effects on Reward Processing in PTSD NCT06096740	University of Texas at Austin	N/A
Completed	PD, PK, and Safety of ALTO-203 in Patients With MDD NCT06391593	Alto Neuroscience	Phase 2
Recruiting	Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succin NCT06270433	Jiangsu Province Nanjing Brain Hospital	N/A
Recruiting	Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression NCT06132581	Florida State University	N/A
Recruiting	Inflammation and Depression in People With HIV NCT05849038	Emory University	Phase 2
Recruiting	Dopaminergic Therapy for Anhedonia - 2 NCT06075771	Emory University	Phase 4
Completed	Prevention of Anhedonia in Children NCT05988138	Vanderbilt University	N/A
Recruiting	Geolocation Positional System (GPS) Experience NCT05991713	University of Miami	N/A
Active Not Recruiting	Promoting Positive Emotional Functioning in Police and Military Populations NCT06035562	University of Manitoba	N/A
Withdrawn	PET Synaptogenesis After Psilocybin In DEpression Recovery NCT05601648	Washington University School of Medicine	Phase 2
Completed	PRISM Neurofeedback Training for MDD Anhedonic Patients NCT05869708	GrayMatters Health Ltd.	N/A
Unknown	REward Processing And Citalopram Study NCT06017037	University of Oxford	Phase 1 / Phase 2
Recruiting	Long-term Efficacy of Pramipexole in Anhedonic Depression NCT05825235	Region Skane	Phase 3
Completed	Pitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study) NCT05849675	University of Oxford	N/A
Completed	Aging and Reward System Response to Inflammation and Anxiety Study NCT05363527	University of California, Los Angeles	Phase 1
Unknown	Mental Imagery and Psychological Well-being NCT05771636	University of Liege	N/A
Active Not Recruiting	Pramipexole for Anhedonic Depression NCT05355337	Region Skane	Phase 3
Completed	A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to NCT05550532	Janssen Research & Development, LLC	Phase 3
Recruiting	Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression NCT07146503	Riccardo Guglielmo	—
Completed	Text Based Digital Interventions Prompting Enjoyable and Healthy Behaviors NCT06492824	Florida State University	N/A
Completed	Investigating LIFUP in Anhedonic Depression NCT06285474	University of California, Los Angeles	N/A
Recruiting	Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia T NCT05240352	The University of Texas Health Science Center, Houston	N/A
Completed	Computational Cognitive Training To Boost Reward Responsiveness In Anhedonic Patients NCT05383248	University of California, San Diego	N/A
Withdrawn	Imagine a Brighter Future: An Intervention to Improve Positive Emotions in Young People NCT05507385	King's College London	N/A
Completed	TMS Alteration of the Reward Positivity NCT05443256	University of New Mexico	N/A
Completed	Individualized Neuromodulation for Anhedonic Depression NCT05537285	University of California, San Diego	N/A
Completed	Anhedonia, Development, and Emotions: Phenotyping and Therapeutics NCT05487885	Erika Forbes	Phase 4
Completed	A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Mo NCT05455684	Janssen Research & Development, LLC	Phase 3
Completed	Serotonin-receptor Agonism in Reward Processing NCT05357547	University of Oxford	Phase 2
Recruiting	Examining the Effects of Estradiol on Neural and Molecular Response to Reward NCT05282277	University of North Carolina, Chapel Hill	Phase 4
Completed	Depressed Mood and Anhedonia in Healthy Adults NCT05306093	Institut Pasteur de Lille	N/A
Completed	Family Promoting Positive Emotions Pilot Study NCT05223842	Vanderbilt University	N/A
Completed	Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD NCT05165394	Neurocrine Biosciences	Phase 2
Completed	The Effects of Wild Blueberries on Depressive Symptoms in Young Adults NCT04647019	University of Reading	N/A
Completed	Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia NCT05084924	University of North Carolina, Chapel Hill	N/A
Completed	Synaptic Imaging and Network Activity in Treatment Resistant Depression NCT05870501	King's College London	N/A
Unknown	Brain Insulin Resistance in Mood Disorders NCT03915613	University Health Network, Toronto	Phase 1 / Phase 2
Unknown	Behavioral Activation Plus Savoring for University Students NCT05234476	Southern Methodist University	N/A
Recruiting	Reward Processing and Depressive Subtypes: Identifying Neural Biotypes NCT06080646	San Francisco Veterans Affairs Medical Center	—
Completed	Feasibility Randomized Controlled Trial Using a 'Leapfrog' Design NCT04791137	Ruhr University of Bochum	N/A
Completed	DTA (Dopaminergic Therapy for Anhedonia) Study NCT04723147	Emory University	Phase 4
Unknown	Motive-specific Intervention for Negative Symptoms in Schizophrenia NCT04793438	University of Zurich	N/A
Completed	A Neurobiological Model of Anhedonia NCT05629520	Milton S. Hershey Medical Center	—
Completed	Evaluating Motivation and Reward Mechanisms and Brain Substrates in Adults With Obesity NCT03939676	Brain and Cognition Discovery Foundation	—
Completed	Pramipexole to Target "Anhedonic Depression" NCT04121091	Region Skane	Phase 2
Completed	Sleep and Healthy Aging Research on Depression for Younger Women NCT03848715	University of California, Los Angeles	Phase 1
Completed	Development of a Novel Transdiagnostic Intervention for Anhedonia - R33 Phase NCT04036136	University of North Carolina, Chapel Hill	N/A
Completed	Translational Model of Anhedonia NCT03856177	University of New Mexico	N/A
Suspended	Mobile Virtual Positive Experiences for Anhedonia NCT03715400	University of California, Los Angeles	N/A
Completed	Effect of D-amphetamine on Reward Functioning NCT03369015	The University of Texas Health Science Center, Houston	Phase 1
Completed	Study to Treat Major Depressive Disorder With a New Medication NCT03043560	James Murrough	Phase 2
Completed	Development of a Novel Transdiagnostic Intervention for Anhedonia - R61 Phase NCT02874534	University of North Carolina, Chapel Hill	N/A
Completed	Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine T NCT02859103	Unity Health Toronto	Phase 4
Completed	Targeting Anhedonia in Cocaine Use Disorder NCT02773212	University of Illinois at Chicago	Phase 2
Completed	The Effect of Computerized Cognitive Training on Mood and Thinking Style Amongst Patients in Inpatient Setting NCT02958228	Ruhr University of Bochum	N/A
Completed	Magnetic Stimulation of the Brain in Schizophrenia or Depression NCT02905604	Uppsala University	N/A
Completed	Dissociating Components of Anhedonia: A Pilot fMRI Study NCT02569034	University of Florida	N/A
Completed	Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic Adolescents NCT02498925	Mclean Hospital	N/A
Completed	Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder NCT02494050	Northwestern University	N/A
Terminated	Kappa Opioid Receptor Imaging in Depression (KOR Depression) NCT02236702	NYU Langone Health	—
Completed	Brain Mechanisms of Emotion and Motivation: A Mind-Body Study NCT01850472	Mclean Hospital	—
Completed	The Effect of CBT- Based Weight Loss Program on Obesity NCT01606904	University of Oulu	N/A
Completed	Depression and Dopamine Transporter Function Study Using C-11 Altropane NCT01701141	Mclean Hospital	—
Completed	Dopamine Neurotransmission in Major Depression NCT01659814	Mclean Hospital	—