Clinical Trials Directory

Trials / Completed

CompletedNCT05165394

Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD

A Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in Major Depressive Disorder (TERPSIS STUDY)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
93 (actual)
Sponsor
Neurocrine Biosciences · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To evaluate the efficacy of NBI-1065846 compared with placebo on improving symptoms of anhedonia in participants with major depressive disorder (MDD).

Conditions

Interventions

TypeNameDescription
DRUGPlaceboTablets for oral administration
DRUGNBI-1065846Tablets for oral administration

Timeline

Start date
2021-11-30
Primary completion
2023-07-07
Completion
2023-09-13
First posted
2021-12-21
Last updated
2024-07-31
Results posted
2024-07-31

Locations

23 sites across 2 countries: United States, Puerto Rico

Regulatory

Source: ClinicalTrials.gov record NCT05165394. Inclusion in this directory is not an endorsement.