| Not Yet Recruiting | Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial NCT07474090 | Wake Forest University Health Sciences | N/A |
| Not Yet Recruiting | Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer NCT05874297 | Fred Hutchinson Cancer Center | N/A |
| Suspended | Circulating Tumor DNA Based Minimal Residual Disease Detection for Patients With Early-Stage Breast Cancer NCT07136493 | City of Hope Medical Center | N/A |
| Recruiting | A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning t NCT07443943 | University of Michigan Rogel Cancer Center | Phase 2 |
| Not Yet Recruiting | Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Mi NCT07191717 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Not Yet Recruiting | Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial NCT05379153 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Not Yet Recruiting | Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and NCT07460752 | Mayo Clinic | Phase 2 |
| Not Yet Recruiting | A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women NCT07331077 | Mayo Clinic | N/A |
| Recruiting | Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, NCT07158021 | University of Michigan Rogel Cancer Center | Phase 2 |
| Recruiting | Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative B NCT06324240 | Emory University | Phase 1 |
| Active Not Recruiting | Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial NCT07407920 | M.D. Anderson Cancer Center | Phase 2 |
| Recruiting | ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Ha NCT06876714 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Recruiting | Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III NCT06954831 | City of Hope Medical Center | Phase 2 |
| Recruiting | The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patient NCT07341503 | Ohio State University Comprehensive Cancer Center | — |
| Recruiting | 5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss NCT07044310 | Mayo Clinic | Phase 2 |
| Active Not Recruiting | Mindfulness Intervention for Improving Nutrition in the Digital Kitchen Among Stage I-III Breast Cancer Surviv NCT06643455 | Fred Hutchinson Cancer Center | N/A |
| Recruiting | Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Bre NCT06635980 | Mayo Clinic | Phase 2 |
| Recruiting | Remotely Delivered, Community-Aligned Weight Loss Interventions Among Breast Cancer Survivors, ¡Vida! Trial NCT05930483 | Fred Hutchinson Cancer Center | N/A |
| Recruiting | Integrative Approaches for Cancer Survivorship (IACS3) NCT06633926 | University of California, San Francisco | N/A |
| Recruiting | Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemother NCT06763328 | City of Hope Medical Center | Phase 3 |
| Recruiting | Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women Wi NCT06534125 | Emory University | N/A |
| Terminated | Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking Endocrine Therapy, VEN NCT06617455 | University of Michigan Rogel Cancer Center | Phase 2 |
| Active Not Recruiting | A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors NCT06392789 | University of Washington | N/A |
| Recruiting | Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 NCT06042569 | City of Hope Medical Center | Phase 2 |
| Suspended | High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breas NCT06538389 | City of Hope Medical Center | Phase 2 |
| Recruiting | Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy NCT06401889 | Mayo Clinic | — |
| Terminated | Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women With Brea NCT06238986 | Mayo Clinic | — |
| Completed | An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutri NCT06193070 | Fred Hutchinson Cancer Center | N/A |
| Recruiting | Breast Cancer, Reasoning, and Activity Intervention NCT04816006 | Mayo Clinic | N/A |
| Recruiting | Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Ni NCT06153836 | Mayo Clinic | Phase 2 |
| Recruiting | Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer NCT05929768 | SWOG Cancer Research Network | Phase 3 |
| Completed | Online Dietary and Resistance Training to Improve Physical Function in Older Cancer Survivors, E-PROOF Trial NCT06016725 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Breast Cancer Survivors Who Experience Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) NCT06106282 | Mayo Clinic | — |
| Recruiting | Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Respo NCT05812807 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Active Not Recruiting | Metformin and Nightly Fasting in Women With Early Breast Cancer NCT05023967 | M.D. Anderson Cancer Center | Phase 2 |
| Active Not Recruiting | Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study NCT05568472 | SWOG Cancer Research Network | N/A |
| Recruiting | Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors NCT05595499 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Terminated | A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adhe NCT05488145 | Emory University | N/A |
| Recruiting | Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV NCT05417308 | Ohio State University Comprehensive Cancer Center | EARLY_Phase 1 |
| Recruiting | Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cance NCT05677802 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Health Coaching-Based Navigation at the Conclusion of Treatment for the Support of Black Breast Cancer Survivo NCT05674578 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Can NCT04593277 | Fred Hutchinson Cancer Center | N/A |
| Recruiting | Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Sta NCT05368428 | Emory University | N/A |
| Recruiting | Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negati NCT05464810 | Emory University | EARLY_Phase 1 |
| Terminated | Precision Performance Status Assessment in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy NCT04835597 | M.D. Anderson Cancer Center | — |
| Recruiting | Neoadjuvant Breast Cancer Time Restricted Eating NCT05327608 | Thomas Jefferson University | N/A |
| Completed | Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer NCT05945290 | Mayo Clinic | — |
| Withdrawn | Diabetes Prevention Program (METFIT) in Reducing Insulin Resistance in Stage I-III Breast Cancer Survivors NCT04560439 | City of Hope Medical Center | N/A |
| Recruiting | Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors NCT05452681 | University of Alabama at Birmingham | N/A |
| Recruiting | A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment NCT05243056 | University of Alabama at Birmingham | N/A |
| Recruiting | Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for NCT04329065 | University of Washington | Phase 2 |
| Recruiting | Breast Cancer Survivorship Biorepository NCT05786664 | University of Southern California | — |
| Active Not Recruiting | Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Mor NCT04993313 | OHSU Knight Cancer Institute | N/A |
| Completed | Tonation Breathing Technique Method to Ease Aromatase Inhibitor-induced Joint and/or Muscle Pain NCT05412953 | Mayo Clinic | N/A |
| Recruiting | Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer NCT05183828 | University of Washington | Phase 4 |
| Recruiting | Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors NCT07259304 | University of Southern California | — |
| Completed | An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors NCT05012176 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Mobile Health to Improve Oral Chemotherapy Adherence Among Women With Breast Cancer NCT05086731 | Emory University | N/A |
| Completed | Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel NCT04862585 | Ohio State University Comprehensive Cancer Center | Phase 2 / Phase 3 |
| Completed | Oxaloacetate for the Improvement of Cognitive Complaints in Stage 0-IIIA Breast Cancer Survivors NCT04290897 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Active Not Recruiting | Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stag NCT04754412 | M.D. Anderson Cancer Center | N/A |
| Completed | Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer NCT04857697 | Mayo Clinic | EARLY_Phase 1 |
| Active Not Recruiting | Web-Based Symptom Monitoring and Self-Management Portal (YES) for Adolescent and Young Adult Breast Cancer Sur NCT04906200 | Ohio State University Comprehensive Cancer Center | N/A |
| Recruiting | Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Bre NCT05928325 | M.D. Anderson Cancer Center | N/A |
| Completed | Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast C NCT04481113 | OHSU Knight Cancer Institute | Phase 1 |
| Active Not Recruiting | Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer NCT04871516 | Rutgers, The State University of New Jersey | N/A |
| Terminated | Registrational Trial to Compare Effectiveness of Two Digital Software Medical Devices as Adjunctive Oncology T NCT04862195 | Blue Note Therapeutics | N/A |
| Completed | Treatment Decision Making in African American Women Diagnosed With Triple Negative Breast Cancer NCT05071677 | M.D. Anderson Cancer Center | — |
| Recruiting | Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early NCT05417867 | Mayo Clinic | — |
| Terminated | Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients NCT04705025 | Jonsson Comprehensive Cancer Center | N/A |
| Completed | Multiscale Omics for the Development of a Cohort Database and Study Platform in Breast Cancer Survivors NCT04999826 | Mayo Clinic | — |
| Active Not Recruiting | Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions NCT04549571 | Alliance for Clinical Trials in Oncology | N/A |
| Active Not Recruiting | Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiv NCT04379570 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Terminated | Health Literacy in Understanding Radiation Therapy Information in Patients Undergoing Definitive Radiation The NCT04927559 | University of Southern California | — |
| Completed | Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer NCT04205903 | Ohio State University Comprehensive Cancer Center | Phase 1 |
| Active Not Recruiting | Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer NCT05025059 | M.D. Anderson Cancer Center | N/A |
| Active Not Recruiting | Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM) NCT04537312 | Ohio State University Comprehensive Cancer Center | N/A |
| Withdrawn | Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal NCT04205071 | Ohio State University Comprehensive Cancer Center | Phase 1 |
| Completed | Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Bre NCT04535323 | Mayo Clinic | Phase 1 |
| Terminated | Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients Wit NCT04249622 | Mayo Clinic | Phase 2 |
| Terminated | RBX7455 Before Surgery for the Treatment of Operable Breast Cancer NCT04139993 | Mayo Clinic | Phase 1 |
| Completed | Interactive Care Plan for the Monitoring of Symptoms and Recovery in Patients With Stage 0-III Breast Cancer NCT04693338 | Mayo Clinic | Phase 1 |
| Recruiting | Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer NCT04517838 | Mayo Clinic | — |
| Active Not Recruiting | Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients NCT04443413 | Mayo Clinic | Phase 3 |
| Terminated | Impact of Breast Cancer Treatment on Joint Health, Cartilage Composition, and Bone Structure in the Knee and H NCT04876378 | University of California, San Francisco | — |
| Completed | Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer NCT04294225 | Mayo Clinic | Phase 2 |
| Completed | Tai Chi for Relieving Aromatase Inhibitor-Induced Arthralgia in Patients With Stage I-III Breast Cancer, the T NCT04716920 | Thomas Jefferson University | N/A |
| Completed | Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Act NCT04200482 | Fred Hutchinson Cancer Center | Phase 2 |
| Terminated | Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With NCT04216472 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Prospective Registry Trial for Single Port Robot-assisted Nipple Sparing Mastectomy (SPrNSM) NCT04866992 | University of Texas Southwestern Medical Center | — |
| Terminated | Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Ca NCT03979508 | Mayo Clinic | Phase 2 |
| Completed | Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple NCT04081389 | Roswell Park Cancer Institute | Phase 1 |
| Completed | Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiv NCT03953157 | Jonsson Comprehensive Cancer Center | N/A |
| Active Not Recruiting | Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer NCT04001829 | ECOG-ACRIN Cancer Research Group | Phase 2 |
| Terminated | Ipilimumab, Nivolumab, and Talimogene Laherparepvec Before Surgery in Treating Participants With Localized, Tr NCT04185311 | Jonsson Comprehensive Cancer Center | Phase 1 |
| Active Not Recruiting | Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer NCT03939481 | SWOG Cancer Research Network | — |
| Active Not Recruiting | Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer NCT04678414 | M.D. Anderson Cancer Center | — |
| Terminated | Exercise and Nutrition Education in Improving Physical Function and Quality of Life in Older Breast Cancer Sur NCT03751449 | Roswell Park Cancer Institute | N/A |
| Completed | Exercise and Diet Counseling Program in Improving Quality of Life in Stage I-III Breast Cancer Survivors NCT04454086 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | EXERCISING TOGETHER for Couples Coping With Cancer NCT03630354 | OHSU Knight Cancer Institute | N/A |
| Completed | Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery NCT03624478 | Mayo Clinic | Phase 2 |
| Active Not Recruiting | A Text-based Intervention in Improving Adherence to Hormone Therapy in Patients With Stage I-III Hormone Recep NCT04086875 | Thomas Jefferson University | N/A |
| Withdrawn | Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Can NCT03666819 | Mayo Clinic | Phase 2 |
| Completed | Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Posi NCT03774472 | M.D. Anderson Cancer Center | Phase 1 / Phase 2 |
| Completed | Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Can NCT03505671 | Wake Forest University Health Sciences | N/A |
| Completed | Stress Test in Detecting Heart Damage in Premenopausal Women With Stage I-III Breast Cancer NCT03505736 | Wake Forest University Health Sciences | — |
| Terminated | Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer NCT02876640 | National Cancer Institute (NCI) | Phase 1 |
| Recruiting | Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With N NCT02918474 | M.D. Anderson Cancer Center | N/A |
| Active Not Recruiting | Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery NCT03012399 | M.D. Anderson Cancer Center | N/A |
| Active Not Recruiting | Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant NCT05049746 | M.D. Anderson Cancer Center | N/A |
| Active Not Recruiting | Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer NCT01334021 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors NCT03708055 | University of Arizona | N/A |
| Completed | Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer NCT00507923 | M.D. Anderson Cancer Center | N/A |