NCT04593277

Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study

INSPIRE-AYA: A Multicenter Interactive Survivorship Program to Improve Healthcare Resources for Adolescent and Young Adult (AYA) Cancer Survivors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 549 (actual)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial studies how well an interactive survivorship program works in improving healthcare resources in adolescent and young adult cancer survivors. By improving access to survivorship resources, health literacy, self-management skills, and support, an interactive survivorship program may help to improve adherence to adolescent and young adult healthcare guidelines and reduce cancer-related distress.

Detailed description

OUTLINE: Patients who have one or more elevated distress or low cardiometabolic or cancer health care adherence are randomized to Arm I or II. ARM I (INTERVENTION): Patients receive a personalized Survivorship Care Plan (SCP) and use the Interactive Survivorship Program to Improve Healthcare Resources (INSPIRE) mobile application. Patients may receive telehealth stepped care after 1 month. ARM II (CONTROL): Patients receive access to a study-specific control website that has annotated links to existing resources for adolescent and young adult (AYA) survivors. After 12 months, patients receive a personalized SCP and have access to the digital INSPIRE intervention program without telehealth calls.

Conditions

• Clinical Stage I Cutaneous Melanoma AJCC v8
• Clinical Stage II Cutaneous Melanoma AJCC v8
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Hematopoietic and Lymphoid Cell Neoplasm
• Invasive Malignant Neoplasm
• Leukemia
• Lymphoma
• Malignant Solid Neoplasm
• Sarcoma
• Stage I Colorectal Cancer AJCC v8
• Stage II Colorectal Cancer AJCC v8
• Stage III Colorectal Cancer AJCC v8
• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Thyroid Gland Carcinoma

Interventions

Type	Name	Description
OTHER	Internet Mobile Technology	Use INSPIRE mobile application
OTHER	Internet-Based Intervention	Access to a study-specific control website
OTHER	Questionnaire Administration	Ancillary studies
PROCEDURE	Supportive Care	Receive telehealth stepped care
OTHER	Informational Intervention	Receive printed SCP materials

Timeline

• Start date: 2022-10-23
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2020-10-19
• Last updated: 2026-01-23

Locations

5 sites across 1 country: United States