| Not Yet Recruiting | Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloi NCT06600880 | Columbia University | Phase 1 |
| Enrolling By Invitation | Cholinergic Deep Brain Stimulation for Alzheimer's Disease NCT05882344 | Vanderbilt University Medical Center | N/A |
| Recruiting | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants NCT07328451 | Denali Therapeutics Inc. | Phase 1 |
| Recruiting | Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease NCT07221344 | Arrowhead Pharmaceuticals | Phase 1 / Phase 2 |
| Recruiting | A Study to Assess THN391 in Subjects With Alzheimer's Disease NCT06814730 | Therini Bio, Inc. | Phase 1 |
| Not Yet Recruiting | Neuropsychological Evaluation in Intellectual Disability (ENDI) NCT07047963 | Central Hospital, Nancy, France | — |
| Withdrawn | SNIFF - 3-Week Aptar CPS Device NCT05006599 | Wake Forest University Health Sciences | Phase 2 |
| Recruiting | Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease NCT07036328 | Willem de Haan | N/A |
| Recruiting | Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease NCT06688968 | University Hospital, Montpellier | N/A |
| Active Not Recruiting | PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) NCT06750432 | ProMis Neurosciences, Inc | Phase 1 |
| Recruiting | A Multifocal TDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia NCT06668610 | University of Campania Luigi Vanvitelli | N/A |
| Recruiting | MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease NCT06099587 | Rennes University Hospital | N/A |
| Terminated | ScentAware and OCT in MCI vs HC NCT06377241 | University of Wisconsin, Madison | — |
| Active Not Recruiting | Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) NCT06268886 | Bristol-Myers Squibb | Phase 2 |
| Recruiting | Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study NCT05573490 | Indiana University | N/A |
| Active Not Recruiting | Effects of a Widely Used Vaccine Adjuvant in Subjects With Early Alzheimer's Disease Double-blind Study to Ass NCT07107074 | ADvantage Therapeutics | Phase 2 |
| Recruiting | Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity NCT06080659 | Rennes University Hospital | N/A |
| Active Not Recruiting | A Pivotal Study of LIPUS-Brain in Patients With Early Alzheimer's Disease NCT05983575 | Sound Wave Innovation CO., LTD. | Phase 3 |
| Active Not Recruiting | The Ketogenic Diet for Alzheimer's Disease NCT04701957 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy NCT05655195 | Massachusetts Institute of Technology | N/A |
| Active Not Recruiting | A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) NCT05637801 | Cognito Therapeutics, Inc. | N/A |
| Recruiting | NYSCF Scientific Discovery Biobank NCT06203106 | New York Stem Cell Foundation Research Institute | — |
| Unknown | Hyperspectral Retinal Observations for the Cross-sectional Detection of Alzheimer's Disease NCT05604183 | Mantis Photonics AB | N/A |
| Completed | Engagement 2.0 Forms of Consent for Data (re-)Use NCT05229978 | Universitair Ziekenhuis Brussel | — |
| Unknown | Eardream Data Collection in Colombia Supported by ADDF NCT05570370 | Swiss Federal Institute of Technology | — |
| Recruiting | The Dampness Syndrome of Chinese Medicine Cohort Study NCT05315895 | Guangzhou University of Traditional Chinese Medicine | — |
| Unknown | Digital Evaluations and Technologies Enabling Clinical Translation for AD NCT05385913 | Oregon Health and Science University | — |
| Recruiting | Donepezil Versus Non-drug Treatment in Alzheimer's Disease. NCT04661280 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty NCT05754021 | Baylor College of Medicine | — |
| Active Not Recruiting | Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study NCT04685590 | Washington University School of Medicine | Phase 2 |
| Recruiting | Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD NCT04500847 | Butler Hospital | Phase 1 |
| Recruiting | MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY NCT04150198 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Unknown | Adapted Home-based Exercise Program "T&E" (Test-and-Exercise) in Persons With Alzheimer's Disease (HOPE Trial) NCT04916964 | HES-SO Valais-Wallis | N/A |
| Recruiting | Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease NCT04804618 | Guangzhou University of Traditional Chinese Medicine | — |
| Completed | Ryan Companion Robot for Assisting Elderly People With Alzheimer's Disease NCT05052866 | DreamFace Technologies, LLC | N/A |
| Completed | A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer' NCT04733989 | GAP Innovations, PBC | — |
| Completed | Pilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease NCT04552795 | The University of Texas Health Science Center at San Antonio | Phase 1 / Phase 2 |
| Recruiting | GnRH Therapy on Cognition in Down Syndrome NCT04390646 | Nelly Pitteloud | Phase 2 / Phase 3 |
| Active Not Recruiting | Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease NCT04122001 | Johns Hopkins University | N/A |
| Unknown | Novel Dementia Biomarkers NCT04427436 | German Center for Neurodegenerative Diseases (DZNE) | — |
| Unknown | Juice Plus Supplement Clinical Trial NCT04656860 | University of Alabama, Tuscaloosa | N/A |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease NCT04100889 | ProgenaBiome | — |
| Enrolling By Invitation | Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia NCT04042532 | Chang Gung Memorial Hospital | N/A |
| Withdrawn | Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients NCT03514875 | University of Nebraska | N/A |
| Unknown | Epileptiform Activity During REM Sleep in Alzheimer's Disease NCT03923569 | University Hospital, Toulouse | N/A |
| Completed | The Effect of Black Mulberry (Morus Nigra) Consumption on Cognitive Functions NCT05406648 | Hacettepe University | N/A |
| Unknown | Efficacy and Safety of AD-35 in Treatment of Subjects With Mild to Moderate Alzheimer's Disease NCT03625401 | Zhejiang Hisun Pharmaceutical Co. Ltd. | Phase 2 |
| Unknown | Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Fun NCT03661034 | Cognito Therapeutics, Inc. | N/A |
| Completed | Efavirenz for Patients With Alzheimer's Disease NCT03706885 | Case Western Reserve University | Phase 1 |
| Completed | Patients With Alzheimer's Disease or Related Youth Disease NCT03508024 | University Hospital, Lille | — |
| Completed | A Safety Study of PTI-125 in Healthy Volunteers NCT03784300 | Pain Therapeutics | Phase 1 |
| Unknown | The Interactive Physical and Cognitive Exercise System NCT03069391 | Union College, New York | N/A |
| Completed | Examining Neuroinflammation in AlzHeimer's NCT03548883 | AdventHealth | — |
| Active Not Recruiting | Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study NCT02740634 | Mayo Clinic | N/A |
| Completed | Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks NCT03153371 | University of California, Los Angeles | — |
| Completed | The Resting-state EEG Gamma Oscillations in Alzheimer's Disease NCT05989087 | Görsev Yener, MD, PhD | — |
| Completed | Effects of Transcranial Magnetic Stimulation (TMS) and Cognitive Training for Alzheimer Patients NCT00909285 | Assaf-Harofeh Medical Center | N/A |
| Completed | Genetic Studies in Familial Dementia NCT04680013 | University of Miami | — |