NCT00909285

Effects of Transcranial Magnetic Stimulation (TMS) and Cognitive Training for Alzheimer Patients

Testing the Effects of TMS Stimulation and Cognitive Training for Alzheimer Patients: A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Assaf-Harofeh Medical Center · Other Government
• Sex: All
• Age: 55 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Current diagnosis of Alzheimer disease is made by clinical, neuropsychological, and neuroimaging assessments. Routine structural neuroimaging evaluation is based on nonspecific features, such as atrophy, which is a late feature in the progression of the disease. Therefore, developing new approaches for early and specific recognition of Alzheimer disease at the prodromal stages is of crucial importance. In the present study the investigators would like to examine if combined treatment with TMS and cognitive training (CoTra) for several weeks can produce a sustained improvement in cognitive and behavioral symptomatology of Alzheimer's disease (AD) patients. A number of in vivo neuroimaging techniques, which can be used to reliably and noninvasively assess aspects of neuroanatomy, chemistry, physiology, and pathology, hold promise.

Conditions

• Alzheimer Disease, Early Onset

Interventions

Type	Name	Description
DEVICE	TMS stimulation	TMS stimulation and cognitive training
DEVICE	Sham comparator	Sham comparator
BEHAVIORAL	Cognitive training	TMS stimulation and cognitive training

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-07-01
• Completion: 2010-07-01
• First posted: 2009-05-27
• Last updated: 2010-07-13

Locations

1 site across 1 country: Israel