NCT06377241

ScentAware and OCT in MCI vs HC

A Proof-of-concept Pilot Study to Determine the Efficacy of SensifyAware and Retinal Imaging in Differentiating Mild Cognitive Impairment (MCI) From Cognitively Unimpaired Controls (HC)

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn whether a new smell test works as well as the standard clinical smell test, if there is a link between sense of smell and variations in the retina, and if these results could be used as a way to identify early stages of Alzheimer's disease. The main questions it aims to answer are: * Whether the test is as effective and reliable as the standard test * Whether there is a link between the results of the smell test and the structure of the back of the eye Participants will: * complete a short questionnaire * have pictures of the inside of their eyes taken * perform two smell tests

Conditions

• Alzheimer Disease, Early Onset

Interventions

Type	Name	Description
DEVICE	ScentAware	ScentAware is a smell test
DEVICE	UPSIT	UPSIT is a smell test

Timeline

• Start date: 2024-04-15
• Primary completion: 2024-06-05
• Completion: 2024-06-05
• First posted: 2024-04-22
• Last updated: 2025-04-23

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study