NCT06302218

ESPB vs iPACK+ACB in Total Knee Arthroplasty

Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Pain Management in Patients Undergoing Total Knee Replacement

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Poznan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Effect of iPACK block with Adductor Canal Block and ESPB on pain management, and NLR and PLR following knee arthroplasty

Detailed description

Knee arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the surgery's induced stress response, opioid consumption, and opioid-related side effects. In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasised. However, very few studies have evaluated the effect of various methods of anaesthesia on the NLR and PLR. This is the first study to investigate the effect of regional anaesthesia on the pain managementonse expres and stress respsed by the NLR and PLR in patients undergoing knee replacement surgery.

Conditions

• Knee Arthritis
• Knee Arthropathy
• Knee Osteoarthritis
• Knee Pain Chronic
• Knee Disease
• Knee Rheumatism

Interventions

Type	Name	Description
DRUG	Ropivacaine 0.2% Injectable Solution	iPACK block + Adductor Canal Block
DRUG	Ropivacaine 0.2% Injectable Solution	Erector Spinae Plane Block
DRUG	control group	only spinal anesthesia

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-09-30
• Completion: 2025-10-30
• First posted: 2024-03-08
• Last updated: 2024-03-08

Locations

1 site across 1 country: Poland