NCT05525390

Extended Reality Behavioral Activation: An Intervention for Major Depressive Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary aims of this study are to assess the feasibility, acceptability, and tolerability of using an immersive extended reality (XR) headset to engage in behavioral activation (BA) for individuals diagnosed with major depressive disorder (MDD). The secondary aim of this study is to explore the efficacy of using XR to enhance BA therapy in a clinical MDD population.

Detailed description

This is a treatment development trial. Participants will be randomized to receive either XR-enhanced behavioral activation or traditional behavioral activation. All groups will follow a brief-BA protocol developed for primary care settings over a four-session, three-week treatment period.

Conditions

• Major Depressive Disorder
• MDD
• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Extended Reality-Enhanced Behavioral Activation	Participants will choose at least four "activities" to complete in Oculus extended reality over the course of the week. These activities are chosen from the Oculus and may include video 360, social interactions, gaming, etc.
BEHAVIORAL	Traditional Behavioral Activation	Participants will choose at least four pleasurable and/or mastery activities to complete over the course of the week in real life.

Timeline

• Start date: 2022-12-19
• Primary completion: 2023-07-24
• Completion: 2023-07-24
• First posted: 2022-09-01
• Last updated: 2025-09-22

Locations

1 site across 1 country: United States