Trials / Not Yet Recruiting
Not Yet RecruitingNCT04889742
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
- Status
- Not Yet Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- Sponsor
- Charite University, Berlin, Germany · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study investiagates deep-regional or superficial hyperthermia to enhance radiotherapy or chemoradiation in patients that suffer recurrent disease after previous radiotherapy.
Detailed description
patients that present a relapse within the previously irradiated volume can be included in this trial. These patients will receive re-irradiation according to clinical guidelines and hyperthermia as study intervention. According to tumor location hyperthermia can either be performed by microwave or by capacitive devices. The primary endpoint of this study is non-inferiority of re-irradiation compared to the initial course of radiotherapy (calculated as time to local failure).
Conditions
- Recurrent Cancer
- Prostate Cancer
- Cervical Cancer
- Anal Cancer
- Sarcoma
- Rectal Cancer
- Neuroendocrine Tumors
- Esophageal Cancer
- Pancreas Cancer
- Squamous Cell Carcinoma
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | loco-regional hyperthermia | loco-regional hyperthermia by the use of microwave, capacitive, or superficial hyperthermia devices. |
Timeline
- Start date
- 2024-05-10
- Primary completion
- 2026-01-01
- Completion
- 2028-01-01
- First posted
- 2021-05-17
- Last updated
- 2023-12-26
Locations
1 site across 1 country: Germany
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT04889742. Inclusion in this directory is not an endorsement.