NCT00335907

Protocol-driven Hemodynamic Support for Patients With Septic Shock

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: National Institute of General Medical Sciences (NIGMS) · NIH
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This research is being done to see if a protocol (a set of orders that determine how much and how quickly a drug/fluid is given) for fluid and drugs used to increase blood pressure (vasopressors) will work better then general clinical practices to improve outcomes in patients with septic shock.

Detailed description

Septic shock is low blood pressure caused by an infection. Sepsis is the most common cause of death in non-cardiac intensive care units, and septic shock is the most severe form of sepsis. Treatment for septic shock includes giving antibiotics, intravenous fluids, and medications to raise the blood pressure (vasopressors). We would like to see if a protocol-driven management strategy for septic shock can shorten time on vasopressors and limit the number of side effects. We have constructed a protocol that will allow the nurse at the bedside, in conjunction with the physician's orders, to adjust the amount of fluids and medications that raise the blood pressure (vasopressors).

Conditions

• Shock, Septic
• Severe Sepsis
• Sepsis

Interventions

Type	Name	Description
PROCEDURE	Fluid and Vasopressor Protocol	A Physician Ordered, Nurse Administered Fluid and Vasopressor Protocol

Timeline

• Start date: 2006-09-01
• Primary completion: 2010-06-01
• Completion: 2011-01-01
• First posted: 2006-06-12
• Last updated: 2010-08-25

Locations

1 site across 1 country: United States