NCT00217165

Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study

Taurine as an Anti-manic Agent: a Double-blind Placebo-controlled Study.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Mclean Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 68 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether the amino acid taurine has effects on mood stability in bipolar disorder.

Detailed description

Taurine is an amino acid that has some actions similar to mood stabilizers. Taurine is widely sold as a component of over-the-counter mood enhancing agents. However, controlled studies examining the mood effects of taurine are limited. An initial study in this laboratory looked at taurine's mood effects in individuals with bipolar disorder. This follow-up study is designed to further examine taurine's effects on manic symptoms. Subjects in the current follow-up study will add taurine or placebo to their current treatment regimen. Both depressive and manic symptoms will be tracked for three months to determine whether the addition of taurine affects mood symptoms.

Conditions

• Bipolar Disorder
• Mania
• Bipolar Depression

Interventions

Type	Name	Description
DRUG	taurine	taurine 2mg BID po

Timeline

• Start date: 2005-04-01
• Primary completion: 2010-01-01
• Completion: 2011-12-01
• First posted: 2005-09-22
• Last updated: 2019-03-01

Locations

1 site across 1 country: United States