Clinical Trials Directory

Trials / Sponsors / Astellas Pharma Global Development, Inc.

Astellas Pharma Global Development, Inc.

Industry · 197 registered clinical trials18 currently recruiting.

StatusTrialPhaseStarted
RecruitingA Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
Phase 1 / Phase 22026-03-20
RecruitingA Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder C
Muscle-invasive Bladder Cancer
Phase 22026-03-12
RecruitingA Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults
Stargardt Disease, Stargardt Macular Dystrophy, Stargardt-like Macular Dystrophy
2026-02-20
RecruitingA Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX C
Pancreatic Cancer, Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
Phase 32026-02-17
RecruitingA Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors
Locally Advanced or Metastatic Malignant Solid Tumors
Phase 1 / Phase 22026-02-05
RecruitingA Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Heal
Healthy Volunteer
Phase 12026-02-03
RecruitingA Study to Evaluate the Safety and Drug Levels of ASP5541 in Chinese Participants With Prostate Cancer
Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer, Metastatic Hormone Sensitive Prostate Cancer
Phase 12026-01-20
RecruitingA Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Can
Pancreatic Ductal Adenocarcinoma
Phase 12025-10-16
Active Not RecruitingA Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer
Metastatic Pancreatic Adenocarcinoma
Phase 12025-09-24
RecruitingA Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer (NSCLC), Anaplastic Lymphoma Kinase (ALK) Positive
Phase 12025-09-22
RecruitingA Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer
Metastatic Urothelial Carcinoma
Phase 42025-06-21
RecruitingA Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer, Metastatic Hormone Sensitive Prostate Cancer
Phase 22025-06-19
RecruitingA Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer
Phase 32025-05-22
CompletedA Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Chinese Women Going Through Menopause
Hot Flashes
Phase 22025-03-10
RecruitingA Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic
Geographic Atrophy, Macular Degeneration
2025-01-22
WithdrawnA Study of ASP1893 in Adults With Advanced CLDN6-positive Solid Tumors
CLDN6-positive Solid Tumor, Ovarian Cancer, Endometrial Cancer
Phase 12024-12-31
CompletedExperiment to Assess Preferences for Novel Hormonal Therapy and Androgen-deprivation Therapy in Prostate Cance
Prostate Cancer
2024-11-22
TerminatedA Study to Find a Suitable Dose of ASP2802 in People With CD20-positive B-cell Lymphomas
B-cell Lymphoma
Phase 12024-09-06
TerminatedA Study to Evaluate the Effects of ASP5502 in Healthy Adults and Adults With Primary Sjögren's Syndrome
Healthy Volunteers, Sjögren's Syndrome
Phase 12024-08-21
Active Not RecruitingA Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone
Hot Flashes
Phase 32024-07-31
TerminatedA Study of ASP1012 in Adults With Solid Tumors
Solid Tumor
Phase 12024-05-15
CompletedA Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidne
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
Phase 32024-03-19
Active Not RecruitingA Study to Learn How Effective and Safe the Drug 'Mirabegron' is and How Long it Stays in the Body of Children
Neurogenic Detrusor Overactivity
Phase 32024-02-28
RecruitingA Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease
Chronic Kidney Disease, Renal Anemia
Phase 32024-01-16
Active Not RecruitingA Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
Hot Flashes
2023-11-15
CompletedA Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
Phase 32023-08-02
RecruitingA Study of ASP1002 in Adults for Treatment of Solid Tumors
Advanced Solid Tumors
Phase 12023-03-13
TerminatedA Study of ASP2074 in Adults With Solid Tumors
Advanced Solid Tumors
Phase 12023-02-28
Active Not RecruitingA Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Ac
Acute Myeloid Leukemia (AML), FLT3-mutated Acute Myeloid Leukemia
Phase 1 / Phase 22023-01-31
CompletedIncidence and Clinical Burden of Erythropoietin Hyporesponsiveness - a Retrospective Database Analysis
Chronic Kidney Disease
2022-11-18
CompletedAvacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy
Geographic Atrophy, Age-Related Macular Degeneration
Phase 32022-09-26
CompletedA Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well
Healthy Volunteers, Renal Impairment
Phase 12022-08-25
RecruitingA Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastro
Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
Phase 12022-06-07
TerminatedA Study to Find a Suitable Dose of ASP8731 and Check for Medical Problems at Each Dose in Healthy Adults
Healthy Participants
Phase 12022-03-07
CompletedA Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men
Healthy Volunteers
Phase 12022-01-21
TerminatedStudy of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants
Ovarian Cancer, NSCLC, ESCC
Phase 1 / Phase 22021-12-23
CompletedA Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People
Renal Impairment, Healthy Volunteers
Phase 12021-12-21
TerminatedA Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (
Urinary Bladder Neoplasms, Carcinoma in Situ, Carcinoma Transitional Cell
Phase 12021-12-07
CompletedStudy of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antige
Advanced Malignancies, Advanced Cancer
Phase 1 / Phase 22021-11-11
WithdrawnA Study to Assess the Safety and Efficacy of ASP8062 as an Add-on Therapy to Buprenorphine/Naloxone in Partici
Opioid Use Disorder
Phase 22021-11-08
CompletedA Study of Fezolinetant to Treat Hot Flashes in Women Going Through Menopause
Vasomotor Symptoms
Phase 32021-11-08
Active Not RecruitingA Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, o
Advanced Solid Tumors
Phase 1 / Phase 22021-10-19
CompletedA Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants Wit
Hepatic Impairment, Healthy Volunteers
Phase 12021-09-13
CompletedSurvey Based Discrete Choice Experiment Study in Prostate Cancer (DECIDER) Study
Prostate Cancer, Metastatic Hormone-sensitive Prostate Cancer
2021-09-03
TerminatedA Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Ext
Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction
Phase 12021-06-14
RecruitingA Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
Prostate Cancer, Metastatic Castration Resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer
Phase 12021-06-14
TerminatedA Study to Evaluate Mirabegron in Pediatric Participants From 5 to Less Than 18 Years of Age With Overactive B
Overactive Bladder (OAB), Pharmacokinetics of Mirabegron
Phase 32021-03-15
CompletedA Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants
Renal Impaired, Gilteritinib, Normal Renal Function
Phase 12021-01-28
CompletedA Study to Assess the Effect of Food With Fezolinetant in Healthy Female Participants
Healthy Subjects
Phase 12020-11-20
TerminatedA Study to Assess ASP0598 Otic Solution Following Topical Application in the Ear in Subjects With Chronic Tymp
Chronic Tympanic Membrane Perforation
Phase 1 / Phase 22020-09-10
Active Not RecruitingA Study to Assess the Safety, Tolerability and Immunological Response of ASP2390 in Adult Subjects Allergic to
Allergic to House Dust Mites
Phase 12020-09-09
TerminatedA Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FM
Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)
Phase 1 / Phase 22020-09-04
CompletedA Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fe
Hepatic Impairment, Healthy Volunteers
Phase 12020-09-02
CompletedA Study to Investigate the Effect of Renal Impairment on the Safety and Tolerability of Fezolinetant Compared
Healthy Volunteers, Renal Impairment
Phase 12020-08-10
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dos
Opioid Use Disorder
Phase 12020-06-30
CompletedA Study to Assess the Effect of a Single Dose of ASP8062 on the Multiple Dose Safety, Tolerability and Pharmac
Opioid Use Disorder
Phase 12020-06-29
Active Not RecruitingEnfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothe
Urothelial Cancer
Phase 32020-03-30
Active Not RecruitingA Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors
Locally Advanced or Metastatic Malignant Solid Tumors
Phase 22020-03-10
CompletedA Study to Assess Bioequivalence of Fezolinetant Formulations in Healthy Female Participants
Healthy Volunteers
Phase 12020-02-20
CompletedA Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-gl
Prostate Cancer
Phase 12020-01-27
CompletedA Study to Assess Isavuconazole Following a Single Dose of Isavuconazonium Sulfate Intravenous Solution Via Na
Healthy Subjects
Phase 12019-09-24
CompletedStudy to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult No
Healthy Volunteers
Phase 12019-09-19
CompletedA Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Ac
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome
Phase 1 / Phase 22019-09-19
CompletedA Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors
Metastatic Cancer, Solid Tumors, Advanced Cancer
Phase 12019-09-03
CompletedA Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucor
Invasive Mucormycosis, Invasive Aspergillosis
Phase 22019-08-22
CompletedA Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free
Healthy Adult Subjects
Phase 12019-07-31
CompletedA Study to Assess Potential Interaction Between ASP8062 and Alcohol in Healthy Adult Subjects
Healthy Volunteers
Phase 12019-07-16
CompletedA Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopau
Hot Flashes
Phase 32019-07-11
CompletedA Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopau
Hot Flashes
Phase 32019-07-10
CompletedA Study to Find Out How Safe Long-term Treatment With Fezolinetant is in Women With Hot Flashes Going Through
Hot Flashes
Phase 32019-07-10
WithdrawnA Study to Assess ASP2713 in Healthy Subjects
Healthy Volunteers
Phase 12019-07-01
CompletedA Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory
Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Phase 1 / Phase 22019-06-19
CompletedA Study to Assess the Relative Bioavailability of Gilteritinib Following a Single Dose of Gilteritinib Mini-ta
Healthy Volunteer
Phase 12019-05-21
CompletedA Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Ma
Incurable Platinum Refractory Germ Cell Tumors, Tumors
Phase 22019-03-19
Active Not RecruitingA Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer
Pancreatic Cancer, Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
Phase 22019-03-15
CompletedA Study to Evaluate Safety, Tolerability and Immune Response in Adolescents Allergic to Peanut After Receiving
Peanut Allergy
Phase 12019-03-12
TerminatedA Study of ASP1951 in Subjects With Advanced Solid Tumors
Advanced Solid Tumors
Phase 12019-01-14
Active Not RecruitingA Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subje
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer
Phase 32018-11-28
CompletedA Study in Healthy Adult Volunteers to Assess the Safety and Pharmacokinetics of an Investigational Imaging Pr
Healthy Subjects
Phase 12018-10-25
CompletedA Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects
Schizophrenia
Phase 22018-07-13
CompletedA Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l I
Advanced Solid Tumors
Phase 12018-07-02
Active Not RecruitingA Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer
Pharmacokinetics of Zolbetuximab, Gastric Cancer, Gastro-esophageal Junction (GEJ) Cancer
Phase 22018-06-29
CompletedA Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Ad
Ureteral Cancer, Urothelial Cancer, Bladder Cancer
Phase 32018-06-27
Active Not RecruitingA Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastri
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer
Phase 32018-06-21
CompletedA Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of ASP6981 in Subjects With
Schizophrenia
Phase 12018-01-22
CompletedZimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)
Stargardt's Macular Dystrophy
Phase 22018-01-12
TerminatedA Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Urologic Neoplasms
Phase 1 / Phase 22017-10-11
CompletedA Study of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients
Hematological Malignancy
Phase 12017-10-02
CompletedA Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pe
Advanced Solid Tumors
Phase 12017-09-08
CompletedA Trial of the FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor Gilteritinib Administered as Maintenance Therapy Fo
Acute Myeloid Leukemia
Phase 32017-08-16
CompletedA Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flash
Menopause, Hot Flashes
Phase 22017-07-19
CompletedA Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MA-0211 in Healthy Adult
Healthy Volunteers
Phase 12017-06-29
TerminatedA Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitati
Mobility Limitation
Phase 12017-06-28
CompletedStudy to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerul
Kidney Transplantation, Primary Focal Segmental Glomerulosclerosis (FSGS)
Phase 22017-05-22
CompletedA Study to Assess the Analgesic Efficacy and Safety of ASP8062 in Subjects With Fibromyalgia
Fibromyalgia
Phase 22017-05-08
TerminatedA Study of ASP8273 in Subjects With Non-small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Recep
Non-small Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor (EGFR) Mutations
Phase 12017-03-24
CompletedA Study to Assess the Analgesic Efficacy and Safety of ASP0819 in Patients With Fibromyalgia
Fibromyalgia
Phase 22017-03-20
CompletedRegistry of Patients Treated With Systemic Mold-Active Triazoles
Invasive Fungal Infection
2017-03-16
WithdrawnA Study for Subjects Who Are Participating in an Astellas-sponsored ASP8273 Study
Subjects With NSCLC With an EGFR Activating Mutation
Phase 22017-02-28
CompletedA Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Thera
Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation
Phase 22017-01-10
RecruitingA Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
Prostate Cancer
Phase 22016-12-22
CompletedA Study to Evaluate Safety, Tolerability and Immune Response in Adults Allergic to Peanut After Receiving Intr
Peanut Allergy
Phase 12016-12-13
WithdrawnA Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid Tumors
Epidermal Growth Factor Receptor (EGFR) Mutations, Solid Tumors
Phase 12016-11-15
TerminatedA Study to Evaluate Escalating Doses of ASP1235 (AGS62P1) Given as Monotherapy in Subjects With Acute Myeloid
Acute Myeloid Leukemia
Phase 12016-11-10
CompletedTo Compare the Effects of Immediate-release Tacrolimus and Astagraf XL on Donor-Specific Antibody (DSA) Format
Kidney Transplantation
Phase 42016-09-09
CompletedA Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Tre
Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Phase 32016-08-01
CompletedA Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 12016-07-25
CompletedA Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary
Chronic Obstructive Pulmonary Disease (COPD)
Phase 22016-06-30
CompletedA Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men With OAB Symptoms While Taking
Benign Prostatic Hyperplasia, Overactive Bladder
Phase 42016-06-13
CompletedA Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance
Prostate Cancer
Phase 22016-06-09
CompletedA Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma
Metastatic Renal Cell Carcinoma
Phase 22016-05-03
CompletedRollover Study for Subjects Who Have Participated in an Astellas Sponsored ASP2215 Trial
Advanced Solid Tumors, Acute Myeloid Leukemia
Phase 1 / Phase 22016-05-03
TerminatedA Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monother
Acute Myeloid Leukemia
Phase 12016-03-29
CompletedA Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP4345 in Patients With Schi
Schizophrenia
Phase 12016-03-28
CompletedA Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Patients With Metas
Metastatic Hormone Sensitive Prostate Cancer
Phase 32016-03-09
CompletedStudy to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid
Advanced Solid Tumors, Pharmacokinetics of 14C-labeled Gilteritinib
Phase 12016-03-04
CompletedA Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP5094 Following Multiple Intravenous Dos
Rheumatoid Arthritis (RA)
Phase 12016-02-23
TerminatedA Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small
Non-small Cell Lung Cancer (NSCLC)
Phase 32016-02-11
CompletedA Study to Assess the Efficacy and Safety of Enzalutamide in Subjects With Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Phase 22015-11-09
TerminatedA Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer After Docetaxel and/or
Metastatic Castration Resistant Prostate Cancer
Phase 42015-10-28
CompletedA Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of AS
Hepatic Impairment, Healthy
Phase 12015-10-23
CompletedA Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Leukemia, Acute Myeloid (AML)
Phase 32015-10-20
TerminatedA Study of ASP2215 in Combination With Erlotinib in Subjects With Epidermal Growth Factor Receptor (EGFR) Acti
Non-Small-Cell Lung Cancer
Phase 1 / Phase 22015-09-08
CompletedDetermination of Levels of Micafungin in Neonates Suffering From Systemic Candidiasis and/or Candida Meningiti
Candidiasis, Systemic, Candida Meningitis
Phase 22015-05-30
TerminatedStudy to Assess Analgesic Efficacy and Safety of ASP3662 in Subjects With Painful Diabetic Peripheral Neuropat
Painful Diabetic Peripheral Neuropathy (PDPN)
Phase 22015-05-27
CompletedObservational Cohort Study of Patients With Castration-Resistant Prostate Cancer (CRPC)
Prostate Cancer, Castration-resistant Prostate Cancer, Metastatic Prostate Cancer
2015-03-27
CompletedA Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma
Lymphoma, Refractory Solid Tumors, Advanced Cancer
Phase 12015-03-23
CompletedA Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnos
Acute Myeloid Leukemia
Phase 12015-01-07
CompletedA Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monother
Relapsed Lymphoid Malignancy, Refractory Lymphoid Malignancy
Phase 12014-10-14
CompletedStudy to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive
Overactive Bladder (OAB)
Phase 42014-10-07
CompletedA Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Gr
HER2 Amplified, Advanced Breast Cancer, Human Epidermal Growth Factor Receptor 2 (HER2)
Phase 22014-09-05
CompletedA Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Relea
Overactive Bladder (OAB)
Phase 42014-07-24
CompletedTreatment Patterns and Key Healthcare Resource Use in Acute Myeloid Leukemia (AML) With or Without FMS-like Ty
Acute Myeloid Leukemia (AML)
2014-06-02
CompletedA Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and
Metastatic Urothelial Cancer and Other Malignant Solid Tumors
Phase 12014-05-14
CompletedA Rollover Study for Subjects That Have Participated in an Astellas Sponsored Linsitinib Trial
Advanced Solid Tumors
Phase 22014-04-16
CompletedA Dose Escalation Study of ASP8273 in Subjects With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Grow
Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations
Phase 12014-04-09
CompletedA Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP366
Pharmacokinetics of ASP3662, Displacement of Radiotracer, Healthy Volunteers
Phase 12014-04-01
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K in Healthy Subjects
Healthy Volunteers, Pharmacokinetics of ASP015K
Phase 12014-03-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole
Pharmacokinetics of Isavuconazole, Healthy Subjects
Phase 12014-01-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and C
Pharmacokinetics of Repaglinide, Pharmacokinetics of Caffeine, Healthy Subjects
Phase 12014-01-01
CompletedA Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk After Experiencing Biochemical F
Prostate Cancer, Castration-resistant Prostate Cancer, Metastatic Prostate Cancer
2013-12-31
CompletedAn Evaluation of a Cytomegalovirus (CMV) Vaccine (ASP0113) in CMV-Seropositive and CMV-Seronegative Healthy Su
Dialysis, Healthy Subjects, Cytomegalovirus Infection
Phase 12013-12-30
CompletedA Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidne
Kidney Transplantation Cytomegalovirus (CMV) Negative Recipients
Phase 22013-11-20
CompletedASG-15ME is a Study of Escalating Doses of AGS15E Given as Monotherapy in Subjects With Metastatic Urothelial
Metastatic Urothelial Cancer
Phase 12013-11-14
CompletedDose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in
Acute Myeloid Leukemia
Phase 1 / Phase 22013-10-09
CompletedA Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects
Healthy Subjects, Pharmacokinetics of ASP015K
Phase 12013-10-01
CompletedA Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Ca
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Phase 42013-09-25
CompletedA Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoin
Cytomegalovirus (CMV)-Positive Recipients, Allogeneic, Hematopoietic Cell Transplant (HCT)
Phase 32013-09-11
CompletedDrug-Drug Interaction Study Evaluating Effects of ASP015K on Rosuvastatin
Healthy Subjects, Pharmacokinetics of ASP015K
Phase 12013-05-01
CompletedRepeat Dose Tolerance Study of Regadenoson in Healthy Subjects
Healthy Volunteers
Phase 12013-05-01
CompletedA Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet
Bioavailability of ASP015K, Healthy Subjects, Pharmacokinetics of ASP015K
Phase 12013-05-01
CompletedA Study to Evaluate the Pharmacokinetics of BAL8728 After a Single Dose of Pyridinylmethyl-14C-Labeled Isavuco
Pharmacokinetics of 14C-labeled Isavuconazonium Sulfate, Healthy Subjects
Phase 12013-04-01
CompletedA Study to Assess the Efficacy and Safety of ASKP1240 in de Novo Kidney Transplant Recipients
Kidney Transplantation
Phase 22013-03-05
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Fida
Pharmacokinetics of Fidaxomicin, Healthy Subjects
Phase 12013-02-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Metformin, Healthy Subjects
Phase 12013-02-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Methotrexate, Pharmacokinetics of 7-hydroxymethotrexate
Phase 12013-02-01
TerminatedStudy to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of
Candidiasis
Phase 32013-02-01
CompletedSafety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gast
CLDN18.2-positive Gastric Adenocarcinoma, CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction, CLDN18.2-positive Adenocarcinoma of Esophagus
Phase 12012-10-16
CompletedStudy to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labele
Pharmacokinetics of 14C-labeled Isavuconazole, Healthy Subjects
Phase 12012-10-01
CompletedA Study to Evaluate the Long-term Safety and Efficacy of ASP015K in Subjects Previously Enrolled in a Phase 2
Arthritis, Rheumatoid
Phase 22012-09-26
TerminatedA Phase 1, Dose Escalation Study to Assess the Safety and Tolerability of ASP9853 With Either Docetaxel or Pac
Pharmacokinetics of ASP9853, Non-hematologic Malignancies
Phase 12012-08-28
WithdrawnA Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Naïve, Symptomatic Patients With M
Metastatic Castration-Resistant Prostate Cancer
Phase 22012-08-01
CompletedDrug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Atorvastatin
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Atorvastatin, Healthy Volunteers
Phase 12012-08-01
CompletedEfficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer
CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction, CLDN18.2-positive Adenocarcinoma of Esophagus, CLDN18.2-positive Gastric Adenocarcinoma
Phase 22012-07-19
CompletedA Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate
Metastatic Castration-Resistant Prostate Cancer
Phase 22012-07-09
CompletedA Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis
Arthritis, Rheumatoid
Phase 22012-06-19
CompletedA Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate
Pharmacokinetics of ASP015K, Food Effect, Healthy Volunteers
Phase 12012-06-01
CompletedA Study To Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of ASP2408 After Multiple
Rheumatoid Arthritis, Pharmacokinetics of ASP2408
Phase 12012-06-01
CompletedDrug-drug Interaction Study Between Lopinavir/Ritonavir and Isavuconazole
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Lopinavir/Ritonavir, Healthy Volunteers
Phase 12012-06-01
CompletedA Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regad
Coronary Artery Disease (CAD)
Phase 32012-06-01
CompletedDrug Interaction Study of Multiple Doses of Isavuconazole and a Single Dose of Bupropion
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Bupropion, Healthy Volunteers
Phase 12012-06-01
CompletedStudy of the Pharmacokinetics of Isavuconazole in Healthy Non-Elderly and Elderly Male and Female Subjects
Pharmacokinetics of Isavuconazole, Healthy Volunteers, Safety and Tolerability in Elderly
Phase 12012-06-01
CompletedDrug Interaction Study of Isavuconazole and Warfarin in Healthy Male Subjects
Pharmacokinetics of Isavuconazole, Pharmacokinetics of S- and R-warfarin, Pharmacodynamics of Warfarin
Phase 12012-06-01
CompletedDrug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Dextromethorphan, Healthy Adult Volunteers
Phase 12012-05-01
CompletedDrug Interaction Study of the Effect of Ketoconazole at Steady State on the Pharmacokinetics of a Single Dose
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Ketoconazole, Healthy Adult Volunteers
Phase 12012-05-01
CompletedA Multiple Dose Escalation Study of ASKP1240 in Subjects With Moderate to Severe Plaque Psoriasis
Psoriasis
Phase 22012-04-30
CompletedDrug Interaction Study of Isavuconazole and Methadone
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Methadone, Healthy Volunteers
Phase 12012-04-01
CompletedDrug Interaction Study of Isavuconazole and Oral Contraceptive Containing Ethinyl Estradiol and Norethindrone
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Ethinyl Estradiol and Norethindrone, Healthy Volunteers
Phase 12012-04-01
CompletedA Dose Escalation Study to Assess Safety, Tolerability and Pharmacokinetics of ASP2409 Following a Single Intr
Rheumatoid Arthritis, Pharmacokinetics of ASP2409
Phase 12012-04-01
CompletedA Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body
Advanced Solid Tumors, Pharmacokinetics of 14C-OSI-906
Phase 12012-03-19
CompletedStudy of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization
Pharmacokinetics of Isavuconazole, Healthy Volunteers
Phase 12012-03-01
CompletedStudy of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.
Pharmacokinetics of Isavuconazole, Healthy Volunteers, Renal Impaired
Phase 12012-03-01
CompletedDrug Interaction Study of Isavuconazole and Digoxin
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Digoxin, Healthy Volunteers
Phase 12012-03-01
CompletedA Study to Assess the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of My
Healthy Subjects, Pharmacokinetics of Isavuconazole, Pharmacokinetics of Plasma Mycophenolic Acid (MPA)
Phase 12012-03-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of
Healthy Subjects, Pharmacokinetics of Isavuconazole, Pharmacokinetics of Prednisolone
Phase 12012-02-01
CompletedBioavailability of ASKP1240 in Healthy Subjects After Intravenous and Subcutaneous Administration of ASKP1240
Pharmacokinetics of ASKP1240, Pharmacodynamics of ASKP1240, Healthy Volunteers
Phase 12012-02-01
CompletedA Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of
Healthy Subjects, Pharmacokinetics of Isavuconazole, Pharmacokinetics of Sirolimus
Phase 12011-11-01
CompletedA Study to Evaluate a Single Intravenous (IV) Dose Using a New Manufactured Clone and Single Ascending Doses o
Pharmacokinetics of ASP2408, Healthy Subjects
Phase 12011-08-01
CompletedA Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP2408 Following Single I
Healthy Subjects, Pharmacokinetics of ASP2408
Phase 12011-01-01
CompletedA Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP4058 Following Single O
Pharmacokinetics of ASP4058, Healthy Subjects, Food Effect of ASP4058
Phase 12010-08-01
CompletedStudy of ASKP1240 After a Single Intravenous Dose at Escalating Dose Levels in Healthy Subjects
Pharmacokinetics of ASKP1240, Healthy Volunteers
Phase 12009-01-01
CompletedStudy of the Pharmacokinetics of ASP1941 and the Effect on Glucose Concentrations in Male and Female Young and
Healthy Volunteers, Pharmacokinetics of ASP1941
Phase 12007-11-01
No Longer AvailableEarly Access Program (EAP) of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutate
Acute Myeloid Leukemia (AML), FMS-like Tyrosine Kinase-3 (FLT3) Mutations
Approved For MarketingExpanded Access Study of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Rel
Acute Myeloid Leukemia (AML), FMS-like Tyrosine Kinase-3 (FLT3) Mutations
Approved For MarketingProvide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Pr
Metastatic Castration-Resistant Prostate Cancer
Approved For MarketingAn Expanded Access Treatment Protocol of Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Ur
Locally Advanced or Metastatic Urothelial Carcinoma (UC)
AvailableEarly Access Program for Zolbetuximab
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma Cancer, Metastatic Gastric Adenocarcinoma Cancer