NCT01582425

Drug Interaction Study of Isavuconazole and Methadone

A Phase 1, Open-Label, Sequential Study of the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Methadone in Healthy Adult Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Astellas Pharma Global Development, Inc. · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The primary purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics (PK) of methadone after single dose administration. The secondary purpose is to assess the safety and tolerability of isavuconazole alone and in combination with methadone.

Conditions

• Pharmacokinetics of Isavuconazole
• Pharmacokinetics of Methadone
• Healthy Volunteers

Interventions

Type	Name	Description
DRUG	Isavuconazole	oral
DRUG	Methadone	oral

Timeline

• Start date: 2012-04-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2012-04-20
• Last updated: 2012-07-02

Locations

1 site across 1 country: United States