NCT02128893

A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

A Phase 1 Randomized Open Label, Parallel Group Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Astellas Pharma Global Development, Inc. · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the effect of multiple doses of esomeprazole on the pharmacokinetics of isavuconazole. In addition, safety and tolerability of isavuconazole alone and in combination with esomeprazole will be assessed

Conditions

• Pharmacokinetics of Isavuconazole
• Healthy Subjects

Interventions

Type	Name	Description
DRUG	Isavuconazole	oral
DRUG	Esomeprazole	oral

Timeline

• Start date: 2014-01-01
• Primary completion: 2014-02-01
• Completion: 2014-02-01
• First posted: 2014-05-01
• Last updated: 2014-05-01

Locations

1 site across 1 country: United States