| Recruiting | Validate the Efficacy and the Safety of the Keikku Electronic Stethoscope for Its Indication and Intended Purp NCT07044128 | Lapsi Health Holding B.V. | — |
| Completed | Comparison of Postoperative Pulmonary Complications Between Smokers and Nonsmokers NCT06982911 | mehmet özkılıç | — |
| Recruiting | Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma NCT06560255 | Professor Klaus Bønnelykke | Phase 3 |
| Recruiting | VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma NCT06570889 | Professor Klaus Bønnelykke | Phase 3 |
| Recruiting | PREcision Medicine Directed Corticosteroids In Children With preSchool Wheeze NCT06580600 | Queen's University, Belfast | N/A |
| Recruiting | Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study NCT05667701 | Rajesh Kumar | Phase 2 |
| Not Yet Recruiting | Luchtbrug Junior: the Next Step NCT05682664 | Radboud University Medical Center | N/A |
| Recruiting | Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital NCT06603584 | Sohag University | — |
| Recruiting | Early Life Intervention in Pediatrics Supported by E-health - SMOKE NCT06311162 | Insel Gruppe AG, University Hospital Bern | N/A |
| Recruiting | The Gut-Lung Axis and Respiratory Illness in Children NCT06271213 | NHS Greater Glasgow and Clyde | — |
| Recruiting | Longitudinal Preschool Wheeze Biomarker Study NCT06237660 | Imperial College London | — |
| Recruiting | Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years NCT06191315 | Sanofi | Phase 3 |
| Recruiting | Video Assisted Study of Salbutamol Response in Viral Wheezing NCT06093152 | University of Oulu | — |
| Recruiting | Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up NCT06106646 | Oregon Health and Science University | — |
| Terminated | Wearable Auscultation Device Validation in Children NCT06112080 | Strados Labs, Inc. | — |
| Recruiting | Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents NCT06201494 | Charles University, Czech Republic | — |
| Unknown | Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing NCT05684848 | Noos S.r.l. | N/A |
| Unknown | Remote Monitoring in Preschool Wheeze NCT05447832 | Imperial College London | — |
| Withdrawn | Sentinel - Triaging Acute Breathlessness Using Multi-Modal Biomarkers NCT05304494 | Sanome | — |
| Active Not Recruiting | Critical Windows in the Development of Asthma Endotypes and Phenotypes in High-Risk Toddlers NCT05210361 | University of Colorado, Denver | — |
| Recruiting | Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates. NCT05063149 | Franciscus Gasthuis | Phase 3 |
| Active Not Recruiting | Bacterial Lysate In Preventing Asthma NCT05064631 | Queen Mary University of London | Phase 2 |
| Completed | Using Tests in Preschool Children With Wheeze to Determine the Need for Inhaled Corticosteroid Therapy. NCT04942483 | Imperial College London | — |
| Terminated | AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department NCT04669288 | University of Arizona | Phase 3 |
| Withdrawn | Bronchodilators for Wheeze in Young Children Presenting to Primary Care: a Randomised, Placebo-controlled, Mul NCT04584034 | UMC Utrecht | Phase 4 |
| Unknown | Clinical Evaluation of AI-aided Auscultation With Automatic Classification of Respiratory System Sounds NCT04208360 | StethoMe | — |
| Unknown | Respiratory Outcome of Infants With or Without Documented Wheezing During Bronchiolitis NCT04811248 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | A 24 Month Observational Study of Infants 3-24 Months, Who Suffer an Acute Episode of Respiratory Infection an NCT03741322 | Duke University | — |
| Unknown | Non-invasive Differential Diagnosis of Noisy Breathing Infants and Toddlers NCT04128592 | Hasselt University | N/A |
| Completed | Safety of LAIV4 in Children With Asthma NCT03600428 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Nasal Resveratrol and Wheezing Episodes in Preschool Children NCT04689412 | University Of Perugia | — |
| Active Not Recruiting | Breast Milk: Influence of the Micro-transcriptome Profile on Atopy in Children Over Time NCT04017520 | Milton S. Hershey Medical Center | — |
| Completed | A Study of the Pharmacokinetics, Safety and Tolerability of Single Doses of VR647 Inhalation Suspension Admini NCT03421730 | Vectura Limited | Phase 1 |
| Unknown | Impedance Pneumography in Assessment of Asthma Control in Preschool Children NCT03377192 | HUS Skin and Allergy Hospital | — |
| Completed | A Methodology Trial Using the VR647 Inhalation System in Pediatric Subjects Who Have Previously Received Inhal NCT04011709 | Vectura Limited | EARLY_Phase 1 |
| Recruiting | Swiss Paediatric Airway Cohort NCT03505216 | University of Bern | — |
| Completed | Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylatio NCT03206710 | Oregon Health and Science University | — |
| Unknown | Nasal Findings in Reactive Airway Diseases NCT03131323 | Assiut University | — |
| Completed | VCSIP Follow-up Study NCT03203603 | Oregon Health and Science University | — |
| Unknown | Pulmonary Epithelium, Immunology and Development of Asthma: Breathing Together NCT04063631 | Imperial College London | — |
| Completed | Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness NCT02148796 | University of Arizona | Phase 2 |
| Completed | Optimizing Vitamin D Status in Children With Wheeze / Asthma (OPTIVIT) NCT02880930 | Queen Mary University of London | N/A |
| Terminated | Efficacy of Intermittent Tiotropium in Early Childhood Wheezing NCT03199976 | Helsinki University Central Hospital | Phase 4 |
| Completed | Nebulized Beclomethasone Dipropionate Improves Respiratory Lung Function in Preschool Children With Recurrent NCT02381158 | Istituto per la Ricerca e l'Innovazione Biomedica | Phase 4 |
| Completed | Fever and Wheezing Events in Children After US Influenza Vaccines Using Text Messaging NCT02295007 | Columbia University | N/A |
| Terminated | Chest Ultrasound of ER Patients With Cough or SOB NCT02269761 | University of Washington | — |
| Completed | A Study to Assess Benign Joint Hypermobility Syndrome in Children With a History of Wheezing or Asthma NCT02163096 | University of Louisville | — |
| Completed | Recurrent Wheezing in Infants: Risk Factors and Prevention With Probiotics. NCT02113072 | Universidade Federal de Pernambuco | Phase 3 |
| Completed | Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants NCT02233985 | Coordinación de Investigación en Salud, Mexico | Phase 4 |
| Completed | Acetaminophen Versus Ibuprofen in Children With Asthma NCT01606319 | Milton S. Hershey Medical Center | Phase 3 |
| Completed | Individualized Therapy For Asthma in Toddlers NCT01606306 | Milton S. Hershey Medical Center | Phase 3 |
| Completed | Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy NCT01601847 | Case Western Reserve University | Phase 4 |
| Completed | Bedside Lung Ultrasound in Young Children Presenting to the Emergency Department (ED) With Wheezing NCT01452945 | Children's National Research Institute | — |
| Completed | Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respirator NCT01272635 | Milton S. Hershey Medical Center | Phase 3 |
| Completed | Secondhand Smoking in Asthmatic Children NCT03099902 | AHEPA University Hospital | — |
| Completed | Wheeze and Intermittent Treatment NCT01142505 | Queen Mary University of London | Phase 3 |
| Withdrawn | A Phase 3 Trial of the Effect of Motavizumab Prophylaxis on Reduction of Serious Early Childhood Wheezing in I NCT00628303 | MedImmune LLC | Phase 3 |
| Completed | Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics NCT01188577 | Amphastar Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Unknown | Wheezometer™ Exploratory (WM) Field Study NCT01156818 | KarmelSonix Ltd. | — |
| Completed | Montelukast for Acute Bronchiolitis and Postbronchiolitis Viral Induced Wheezing NCT01370187 | Hormozgan University of Medical Sciences | N/A |
| Terminated | Effectiveness of Inhaled Corticosteroids in Preschool Children With Acute Dyspnea and Wheeze NCT00962299 | Princess Amalia Children's Clinic | Phase 4 |
| Unknown | Montelukast in Children With Wheezing NCT00775697 | Universita di Verona | Phase 4 |
| Completed | Allergy Immunotherapy for the Reduction of Asthma NCT01028560 | Albert Einstein College of Medicine | Phase 1 / Phase 2 |
| Completed | Effect of Palivizumab on Later Recurrent Wheezing in Preterm Infants NCT01072552 | Satoshi Kusuda | — |
| Completed | A Post Marketing Evaluation of the Effectiveness of FluMist Risk Minimization Plan in Children NCT00626808 | MedImmune LLC | — |
| Completed | Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing NCT00749528 | Kecioren Education and Training Hospital | — |
| Completed | The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Wheezing\Coughing Babies NCT00512382 | Wolfson Medical Center | — |
| Completed | Polish Mother and Child Cohort Study (REPRO_PL) - Follow up of the Children. NCT01861548 | Medical University of Lodz | — |
| Completed | Lung Function and Structure in Healthy Infants and Infants With Recurrent Wheezing NCT00507676 | Indiana University School of Medicine | — |
| Unknown | Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children NCT00494624 | University of Turku | Phase 4 |